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Medical Forum / Diseases and Disorders / Cancer / April 2005C/T bad news
just back from the onc. latest C/T shows multiple new hepatic lip lesions consistent with hepatic metastases. the liver is more heavily involved. they intend to start a new round of chemo next week, but not particularly hopeful.  Signature"...Life is not a journey to the grave with the intention of arriving safely in one pretty and well preserved piece, but to slide across the finish line broadside, thoroughly used up, worn out, leaking oil, and shouting GERONIMO!!!" -- Bill McKenna, date unknown > just back from the onc. latest C/T shows multiple new hepatic lip lesions > consistent with hepatic metastases. the liver is more heavily involved. :-( I'm sorry to read the news, Socks. The liver is a fairly big organ. Hopefuly it'll hang in there for some time, at least until after the Wales trip. Congrats to figgertoes on new job. > they intend to start a new round of chemo next week, but not particularly > hopeful. I wonder if Steph would comment. My brain's thinking "doubling time".. I have been reading your posts. Good to read that permanent pain relief is planned for MOnday. Excellent update to webpage. Thanks for posting that. ( ( ( Socks & figgertoes ) ) ) J >> just back from the onc. latest C/T shows multiple new hepatic lip >> lesions consistent with hepatic metastases. the liver is more [quoted text clipped - 3 lines] > The liver is a fairly big organ. Hopefuly it'll hang in there for some > time, at least until after the Wales trip. This was the most likely way that i was going to go out, and it wasn't particularly surprising, other than surprising that i lasted this long. They are going to throw navelbene and something else at it (gemcitabene?). I went looking for data. Lots of data on gemcitabene but not much on navelbene. With gemcitabene trials, median life expectency from start of chemo on advanced metastatic cancers was 5.7 monthes. > Congrats to figgertoes on new job. she got home from the first day without being fired. guess there is hope there. >> they intend to start a new round of chemo next week, but not >> particularly hopeful. > > I wonder if Steph would comment. > My brain's thinking "doubling time".. me too. > I have been reading your posts. > Good to read that permanent pain relief is planned for MOnday. > Excellent update to webpage. Thanks for posting that. > ( ( ( Socks & figgertoes ) ) ) > J one can hope it will work Signature"...Life is not a journey to the grave with the intention of arriving safely in one pretty and well preserved piece, but to slide across the finish line broadside, thoroughly used up, worn out, leaking oil, and shouting GERONIMO!!!" -- Bill McKenna, date unknown just started gemcitabine/navelbine every other week, two weeks ago. first course resulted in 'chemical phlebitis'. took out about 10-12 inches of the vein they put it in. got a port-a-cath yesterday and got second round today. cath works great. no pain, aching, etc. my advice is to get a central line (port-a-cath) before you do the first round. navelbine is a vessicant and gemzar is an irritant. i get 1 1/2 liters of normal saline with each course. wray =============================================== >>> just back from the onc. latest C/T shows multiple new hepatic lip >>> lesions consistent with hepatic metastases. the liver is more [quoted text clipped - 32 lines] > > one can hope it will work > just started gemcitabine/navelbine every other week, two weeks ago. > first course resulted in 'chemical phlebitis'. took out about 10-12 inches [quoted text clipped - 5 lines] > navelbine is a vessicant and gemzar is an irritant. > i get 1 1/2 liters of normal saline with each course. Good to hear from you, wray. Goodness me, it's been ages. Best wishes and keep in touch, J > just back from the onc. latest C/T shows multiple new hepatic lip lesions > consistent with hepatic metastases. the liver is more heavily involved. > they intend to start a new round of chemo next week, but not particularly > hopeful. Just make sure that they can give you a good reason for more chemo Socks, rather than "more disease, therefore more chemo" knee jerk. Remember that there are only 3 reasons to take treatment: 1) Cure 2) Improved survival 3) Improved quality of life. If they can't assure you there is evidence for one of thoses, you should think very carefully about it............. > Just make sure that they can give you a good reason for more chemo > Socks, rather than "more disease, therefore more chemo" knee jerk. [quoted text clipped - 5 lines] > If they can't assure you there is evidence for one of thoses, you > should think very carefully about it............. i've been doing my own digging, which is by no means done. however, I found one study in the UK (BSC == best supportive care, QL == quality of life): "Patients treated with gemcitabine + BSC reported better QL and reduced disease-related symptoms compared with those receiving BSC alone. These improvements in patient-assessed QL were significant in magnitude and were sustained." Signature"...Life is not a journey to the grave with the intention of arriving safely in one pretty and well preserved piece, but to slide across the finish line broadside, thoroughly used up, worn out, leaking oil, and shouting GERONIMO!!!" -- Bill McKenna, date unknown > "Steph" <steph@vancouvers.island> wrote in > [quoted text clipped - 15 lines] > improvements in patient-assessed QL were significant in magnitude and were > sustained." Socks, on March 3rd Steph told us that "It's been known for a long time that patients in clinical trials do better than those not in trials. But this applies to patients getting the control arm, too, so it probably is not a treatment effect " So it seems to me that the BSC = QL which you can get with hospice and/or pain specialist. I don't want to talk you out of more chemo. I'm concerned that it won't really get you any further. IMaybe even steps back.. http://www.cancercare.on.ca/pdfdrugs/gemcitab.pdf J > just back from the onc. latest C/T shows multiple new hepatic lip lesions > consistent with hepatic metastases. the liver is more heavily involved. > they intend to start a new round of chemo next week, but not particularly > hopeful. Sorry to hear that Socks and sincerely hope that chemo can give you more time and more quality. Warm Hugs Alayne > Sorry to hear that Socks and sincerely hope that chemo can give you > more time and more quality. thanks. clinical trials reported significant improvement in quality of life. Difference in life spam though was within the margin of error. Median average says I'll make it through the summer but not much more. Signature"...Life is not a journey to the grave with the intention of arriving safely in one pretty and well preserved piece, but to slide across the finish line broadside, thoroughly used up, worn out, leaking oil, and shouting GERONIMO!!!" -- Bill McKenna, date unknown > > Sorry to hear that Socks and sincerely hope that chemo can give you > > more time and more quality. > > thanks. clinical trials reported significant improvement in quality of > life. Difference in life spam though was within the margin of error. > Median average says I'll make it through the summer but not much more. You're one cool critter Socks and a pleasure to "know". You've passed the finishing post before now and I sure hope that you can do so again, you are certainly an inspiration to others. Warm Hugs Alayne totallyfake@emailaddress.com said... > You're one cool critter Socks and a pleasure to "know". You're not wrong there Alayne. Socks - you ain't goin' nowhere. Leastways, not just yet. We ain't ready to say goodbye and that's that. SignatureIf you can keep your head when all around are losing theirs... then you've failed to grasp some important aspect of the situation. agent01413@my-deja.com said... > Median average says I'll make it through the summer but not much more. So you're putting your trip off - why, exactly? SignatureIf you can keep your head when all around are losing theirs... then you've failed to grasp some important aspect of the situation. > agent01413@my-deja.com said... >> Median average says I'll make it through the summer but not much more. >> > So you're putting your trip off - why, exactly? Socks If I were you I'd book the trip - she ain't gonna stop till you land in Wales! <g> Best of wishes Sinead Sinead@invalid.anon said... > > agent01413@my-deja.com said... > >> Median average says I'll make it through the summer but not much more. [quoted text clipped - 5 lines] > If I were you I'd book the trip - she ain't gonna stop till you land in > Wales! <g> 'Sides which, the house needs cleaning and if Socks doesn't come and visit the incentive will have gone ;-) SignatureIf you can keep your head when all around are losing theirs... then you've failed to grasp some important aspect of the situation. agent01413@my-deja.com said... > just back from the onc. latest C/T shows multiple new hepatic lip lesions > consistent with hepatic metastases. the liver is more heavily involved. > they intend to start a new round of chemo next week, but not particularly > hopeful. Sh*t. Better make the trip in June then instead of May - or wait until the children have gone back to school after the summer break. What are you doing in September? SignatureIf you can keep your head when all around are losing theirs... then you've failed to grasp some important aspect of the situation. |
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