Hello Michael and welcome to alt.support.cancer

Stage 4 colon cancer is what you mean.  Meaning it has spread to other organs.
It's my understanding that holistic means "whole body".
That's what radiation oncologists do, treat what they can without negatively
affecting the whole body too much.
There are side effects with aggressive chemos, no doubt. Some can be controlled
with medications.
There's also palliative (lower) doses of chemo which can help with symptoms.

If she's decided no chemo at all, the other holistic approach, that I know of,
is calling in hospice (palliative care).
They'll be in the yellow pages of her phone book in Minneapolis (or wherever
she decides she wants to end her days).
If she has no symptoms at all right now, perhaps she'd want to investigate
such, set things up for when she does, then take time out to do what she's
always wanted to do, visit relatives, travel or whatever is on her list.

Keep in touch and let us know how you and she are doing.
Best,
J

Inoperable may not mean untreatable, and even when no curative
treatment is know, there's palliative care. You have my sincerest
sympathy.  

The Bloch Foundation, http://www.blochcancer.org has advice for patients
and supporters on-line and off-line. Dick Bloch is himself a survivor of
lung cancer.

4435 Main Street, Suite 500, Kansas City, MO 64111
816-WE BUILD (816-932-8453), 1-800-433-0464,  Fax 816-931-7486

Cancer Care: http://www.cancercareinc.org/ 
40 plus full-time social workers offer counseling
for psychological and financial issues, and referrals to support
groups.