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Medical Forum / Diseases and Disorders / Cancer / April 2004

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CA125 and Chemo Question

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Steven Wandy - 02 Apr 2004 20:06 GMT
My daughter (age 26) was diagnosed with ovarian cancer.
She had one ovary removed and 3/4 of the other - surgeon at Sloane
originally felt safe leaving the part because they thought the cancer was
"borderline". Turns out it is not and they will probably remove the
remaining piece of ovary after the chemo.
Her CA125 was never really elevated - only 38 before the surgery. (That's
why they originally thought it was not even cancer, probably endometriosis.)
She is now at Sloane for her third round of chemo. The doctor told her that
in the blood work-up prior to her second round her CA125 was UP slightly -
43. Doctor did not seem overly concerned - especially since Jen just
finished her period a few days before the blood test/chemo. She is ordering
another CAT scan just for precautionary reasons.
Now I realize that Jen's CA125 was never really high. The doctors at Sloane
explained that they will just have to treat her test results differently
than the "average" - lower the "bell curve" for Jen. It is usual for the
CA125 to go up because a woman has her period? Also, after how many chemo
treatments does the CA125 start to go down?
Thanks for taking the time to read this (and hopefully reply).
Concerned Daddy
J - 02 Apr 2004 21:27 GMT
> My daughter (age 26) was diagnosed with ovarian cancer.
> She had one ovary removed and 3/4 of the other - surgeon at Sloane
[quoted text clipped - 15 lines]
> Thanks for taking the time to read this (and hopefully reply).
> Concerned Daddy

Hi Steven,

Here's what seer says
http://training.seer.cancer.gov/module_diagnostic/unit03_tumor_markers.html
CA-125 (Cancer Antigen-125) a tumor marker useful for monitoring for ovarian
cancer by measuring an antigen to epithelial neoplasms circulating in blood
serum. Normal range: 0 - 35 U/mL. Normal range may vary somewhat according to
institutional experience. Levels above 35 suggest the presence of ovarian
tumor."

So I don't know the answer. I suspect they watch for "trends" over a period of
time.
I guess, my questions would be,
how many rounds of chemo are planned and
would the CA-125 level changes, in any way, change her plans for treatment?

Watch for reply from Steph
Best,
J
claddles - 06 Apr 2004 01:53 GMT
> > My daughter (age 26) was diagnosed with ovarian cancer.
> > Now I realize that Jen's CA125 was never really high. The doctors at Sloane
[quoted text clipped - 24 lines]
> Best,
> J

The best site for information regarding OVCA is http://www.acor.org/.
There is very strong, positive and informed group of woman and carers
who will answer all your questions and give support.
 
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