Hi Richy,
I'm afraid this is too complex for me and perhaps beyond the scope of
this newsgroup but I've found the following to perhaps start your
searching

http://www.chinadaily.com.cn/english/doc/2004-03/09/content_314161.htm
This new injectable medication, uses an adenoviral vector and p53 tumor
suppressor gene. It is a new treatment for head and neck cancer, also
called squamous cell carcinoma (HNSCC).
Gendicine was used in clinical trials on patients with late-stage HNSCC.
After eight weeks of therapy involving one injection per week, about 64
per cent of patients' tumors experienced complete regression and 32 per
cent experienced partial regression. In combination with chemo- and
radiotherapy, Gendicine improved treatment efficacy more than 3-fold.
To date there are more than 700 gene therapy medicines in clinical trial
but Genedicine is the only one with approval to commercialize

<http://www.hhmi.org/cgi-bin/askascientist/highlight.pl?kw=&file=answers%2Fgeneti
cs%2Fans_023.html>

http://www3.cancer.gov/intra/LHC/p53ref.htm

http://www.newscientist.com/news/news.jsp?id=ns99994420
Many tumours arise after the mutation or inactivation of p53, and in
cancers of this type restoring the protein should kill the tumour cells.
This approach has already been tried in the US, with mixed results.

Here's some links to clinical trial searches
http://www.trialscentral.org/
http://www.clinicaltrials.gov/
http://ccr.ncifcrf.gov/trials/patients/

There are perhaps others  cholangiocarcinoma who check this newsgroup's
subject lines for posts, so if you want to gete their attention, please
post again with the type of cancer in the subject line.

Meantime, keep in touch and let us know how you and your father are
doing.
If we can be of assist in any other way, we'll sure try to
Best,
J