I keep meaning to ask my doctors, just seems I always forget, might be my
subconscious not wanting to know.

My original biopsy showed two tumors (Infiltrating lobular carcinoma with
focal closely associated infiltrating ductal carcinoma), with a total size
of 1.5x1.5x0.8 cm, The entire amount they took out was 2.9x2.5x1.4 cm, if
I'm reading this right.  The margins were not clear and was followed up with
a lumpectomy removed 3.6x2.5x1.7 cm, again the margins were not clear.

Final Diagnosis stated:

1. Residual infiltrating ductal carcinoma (0.6 CM), moderately
differentiated (tubles = 3 + nuclei = 2 + mitosis = 1 = 6), present at
surgical margin of resection
2.  Residual ductal carcinoma in-situ, solid type, nuclear grade II of III,
present within less than 0.5 MM of surgical margin

Nodes were negative (good, good, good)

Biopsy stated well differentiated, this one states moderately
differentiated.

DNA Panel
ER = 93% (good, good, good)
HER-s/neu = Normal limit (good, good, good)
Ki-67 = 5%

Questions:
1.  What is the significance of well differentiated vs moderately
differentiated, does this imply that from the first surgery to the second
things took a turn for the worse?
2.  Does the fact that the margins have not been clear alter the stage?
3.  What stage would this be considered?
4.  What does the Ki-67 represent

Thanks again for all your information

Ruth