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Medical Forum / Diseases and Disorders / Breast Cancer / January 2004

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Does three times of chemotherapy enough?

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green tea - 14 Jan 2004 03:34 GMT
Hi, anybody would like to help me?

I have done the operation and took three times of chemotherapy. Berfore the
operation, I took also three times of chemotherapy. And my doctor told me
that the normal treatment is six times. But she told me NOW to take another
three times of chemotherapy. Though I remember that she agreed that I need
only take the left three times of chemotherapy after the operation. Is it
need recalculate after operation?! I have had enough side effect of the
chemotherapy, and I would not like to take the radiation, too.

My case is pure breast cancer, in early stage I, the operation result is:
all negative but the center of the lump. the lump is 1.5*1.0cm. Before the
chemotherapy of the first time, under the molybdenum photo, is 2*3cm. My
doctor told me that the chemotherapy is very effective. But now she said: if
not take the left 3 times of chemotherapy, I should be responsible for the
in case recrudesce years lator on myself, which is bad word for me.

What should I do? On my own point of view, I consider the side effect could
me more serious to me, but what if I take the "left three times of
chemotherapy"? Could you kindly give me some fact or number of probabilities
of the different situation?

Thank you very much.

Green Tea

One more small question: My son bring me some protein powder, is it helpful?
unless? or may be some mixable effect, there ? Thank again?
Tim Jackson - 14 Jan 2004 09:26 GMT
> Hi, anybody would like to help me?
>
[quoted text clipped - 24 lines]
> One more small question: My son bring me some protein powder, is it helpful?
> unless? or may be some mixable effect, there ? Thank again?

If you only do half the chemotherapy you will get much less than half the
benefit, as there are likely to be cancer cells around which were dormant
during the chemo and which will soon wake up and kill you.  The main purpose
of the chemo is not the shrinking of the tumour before surgery, that is
secondary, it is to destroy the free cancer cells floating around in your
blood and settling in various organs around your body.

I don't know percentages for doing partial chemo but I would guess your
survival chances would be less than half what they would be with full chemo,
with a 3cm tumour perhaps 30%, to pull a figure out of the air as opposed to
perhaps 70% with full chemo.  I am not a doctor and I am guessing.

If the side effects are really unbearable then talk to your oncologist about
what can be done to alleviate them, but don't give up on the chemo, we are
talking about life and death here.  What sort of side effects are you
suffering?  If it is a matter nausea and vomiting, what sort of anti-nausea
medications are you getting?

The side effects of radiation are pretty minor, usually nothing worse than
sunburn and a bit of tiredness.  The main "side effect" most people have
with radiation is the inconvenience of several trips to the hospital when it
is far away.

As to protein powder, it is only helpful if you are not getting enough
protein in your diet, which is a risk if you are a vegetarian.  I don't
think it will have much effect on the cancer or the chemotherapy either way.
But as a general rule, ask your oncologist before taking any supplements or
'natural' remedies during chemotherapy.

Tim Jackson
A. P. Thorsen - 14 Jan 2004 16:41 GMT
> "green tea" <greentea@tom.com> wrote in message

>>One more small question: My son bring me some protein powder, is it
>> helpful?
[quoted text clipped - 4 lines]
> But as a general rule, ask your oncologist before taking any supplements or
> 'natural' remedies during chemotherapy.

Tim gives good advice there; I'd add that if the protein powder contains
soy (some do, some don't) you might want to be extra cautious.  If you
have an estrogen receptor postive (ER+) tumor, there is mixed scientific
evidence about whether soy (with its phyto-estrogens) is a good thing or
a bad thing.  Small amounts of soy shouldn't be a major problem, but
some of the protein powders have large amounts of soy.

Personally, speaking as a vegetarian, I don't use protein powder because
it tends to taste *yucky*!

Ann T.
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Marilyn - 14 Jan 2004 18:02 GMT
>> "green tea" <greentea@tom.com> wrote in message
>
[quoted text clipped - 19 lines]
>Ann T.
>Remove 'dontsendspam' from address to reply by email

My tumor was ER+, and I'm a low-carb eater, so I use whey-based protien
powder as a snack. It isn't too bad mixed with some cream and a few
strawberries.  

Marilyn

A. P. Thorsen - 14 Jan 2004 18:08 GMT
>>+
>>Personally, speaking as a vegetarian, I don't use protein powder because
[quoted text clipped - 3 lines]
> powder as a snack. It isn't too bad mixed with some cream and a few
> strawberries.  

<Grin> Even *sawdust* isn't too bad mixed with some cream and a few
strawberries -- high fiber, too!

Seriously, I'll have to check out the whey-based powder.  Are you in the
U.S.?  If so, so do have a brand name or something to look for?

Thanks -

Ann T.
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Marilyn - 15 Jan 2004 00:08 GMT
>> On Wed, 14 Jan 2004 11:41:14 -0500, "A. P. Thorsen"

>>>Personally, speaking as a vegetarian, I don't use protein powder because
>>>it tends to taste *yucky*!
[quoted text clipped - 12 lines]
>
>Ann T.

You can get the brand name "Designer Protein" at GNC, if you have that
chain in the US (I'm in Canada). Designer Protein comes in flavours, like
French Vanilla and Chocolate.   And I've seen plain unflavoured whey powder
in bags at health food stores and "Bulk Barn" stores.  Just check to make
sure it says whey rather that soy.

I never noticed how much soy is sneaking into our food until I got breast
cancer and couldn't have it.  (Insert nasty comment about Monsanto here)

Marilyn
A. P. Thorsen - 15 Jan 2004 15:43 GMT
>>>On Wed, 14 Jan 2004 11:41:14 -0500, "A. P. Thorsen"
>
>>I'll have to check out the whey-based powder.  Are you in the
>
> You can get the brand name "Designer Protein" at GNC, if you have that
> chain in the US (I'm in Canada).

Thanks, Marilyn -- we do have GNC, and I can also look for the generic
at the health food stores.  Now that I'm working out a bunch more, I
sometimes worry whether I'm getting enough protein.  This could be a help!

Ann T.
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bartalo@webtv.net - 14 Jan 2004 18:25 GMT
>I don't know percentages for doing partial
> chemo but I would guess your survival>chances would be less than half
what
> they would be with full chemo, with a 3cm
> tumour perhaps 30%, to pull a figure out of
> the air as opposed to perhaps 70% with full
> chemo. I am not a doctor and I am guessing.
Tim Jackson

Tim, what do you mean by "partial chemo" vs "full chemo"?  I thought the
number of times one gets chemo treatments depends upon each individual
case and the type of Chemo your Oncologist decides to use.  

In my case after the surgery, my Onc decided that 4 Chemo treatments
instead of the regular 6 was enough and I had one positive lympnode. He
used the Adriamycin, Cytoxen, Taxotere (sp) etc. stuff so I figured he
felt he had done enough with the Chemo.  Of course I followed it up and
still am with the 35 radiation treatments and then will be on Tamoxifen
if I can adjust to it..  But my point is that you seem to suggest there
is a set number of Chemo treatments necessary for everyone (unless I am
misunderstanding your post) and from my experience there was not.   Does
that mean I should be concerned I did not get enough Chemo?   In the
end, what it all amounts to is either we trust our Oncologist or we
don't.  


Green Tea....if you are concerned about what your Oncologist wants to do
with extra Chemo, why don't you get a second opinion?   That would help
you to know if you really need to undergo more Chemo.    As Tim stated,
this is your life your are talking.  I think getting a second opinion
would at least let you know if the extra Chemo is truly necessary.

Bea
Tim Jackson - 14 Jan 2004 19:48 GMT
> >I don't know percentages for doing partial
> > chemo but I would guess your survival>chances would be less than half
[quoted text clipped - 3 lines]
> number of times one gets chemo treatments depends upon each individual
> case and the type of Chemo your Oncologist decides to use.

...
> But my point is that you seem to suggest there
> is a set number of Chemo treatments necessary for everyone (unless I am
> misunderstanding your post) and from my experience there was not.   Does
> that mean I should be concerned I did not get enough Chemo?

I mean the full course of the treatment as prescribed by the oncologist.
What is a sufficient number of doses depends on how often they are given,
and the division rate of the cancer (which may not be known).  A more
fast-growing cancer could, at least in theory, be hit by a shorter regime of
chemotherapy.  As it is not possible to know the division rate accurately, I
think there must be a certain amount of rule-of-thumb or one-size-fits-all
prescribing.

In this case the oncologist was clearly unhappy about curtailing the
treatment, and so I presume she thought that the duration was inadequate to
its purpose.

Tim
bell-lady - 15 Jan 2004 04:40 GMT
Tim,
20 years ago when I had adriamycin/cytoxan it was 12 doses over a year. When
I wanted to give up in the middle I was told that once it was given, and
stopped, it couldn't be given again (presumably it would be ineffective??).
I had to take all the doses now, and never have it again; or stop now and
still never have it again (with the same drugs). That may be what is meant.

IMHO Ann
Tim Jackson - 15 Jan 2004 09:01 GMT
> Tim,
> 20 years ago when I had adriamycin/cytoxan it was 12 doses over a year. When
> I wanted to give up in the middle I was told that once it was given, and
> stopped, it couldn't be given again (presumably it would be ineffective??).
> I had to take all the doses now, and never have it again; or stop now and
> still never have it again (with the same drugs). That may be what is meant.

Well there is a lifetime limit for A/C and most chemo combinations.  I think
current treatment plans leave some room for manoeuvre, but if you have done
half a course then there probably isn't room for another whole one without a
major risk of serious side effects, and as I was explaining, two half
courses is nothing like as effective as one whole one because of
synchronisation.  I'm not sure how half an old 12-month sequence would
compare to a modern 6-month one.

Tim
 
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