Does anyone know if a woman can be tested ahead of time (before bc) to
find out if she is ER+? I have a daughter who I am concerned about. I
know her risks of bc are higher now since I have been diagnosed but
when she gets into menopause and the gyn wants to give her estrogen (as
they did me) shouldn't they test her first? I don't think all those
years of taking that Premarin helped my body if I was unknowingly ER+
and I fear it may have increased my chances of getting the bc.
If there is a test, does anyone know what it is called and is it a blood
type test? Thanks!
Bea
A. P. Thorsen - 14 Jan 2004 19:40 GMT
> Does anyone know if a woman can be tested ahead of time (before bc) to
> find out if she is ER+?
Bea, strictly speaking, it was your tumor rather than yourself that was
ER+ . . . and you can't test the tumor until there *is* one.
I had ER+ tumors, and could later develop ER- ones (as could any of us).
You may be thinking of genetic testing to find out whether your daughter
has one of the genes that is associated with increased risk of breast
cancer. If your daughter had the gene(s), she would be at higher risk .
. . but not 100% guaranteed to get BC, I believe. On the other hand,
most women who *do* get BC, *don't* have the known gene(s) -- something
else is behind their getting BC.
I think doctors will be more conservative about prescribing estrogen
than they were in the past, given recent research results. And,
personally, if my mother had had BC (she did; died of it), I wouldn't
take estrogen unless the condition it was treating was also
significantly life-threatening.
I hope they may find other ways to relieve severe menopause symptoms, so
your daughter won't have to make that choice!
Ann T.
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Tim Jackson - 14 Jan 2004 20:10 GMT
> Does anyone know if a woman can be tested ahead of time (before bc) to
> find out if she is ER+? I have a daughter who I am concerned about. I
[quoted text clipped - 8 lines]
>
> Bea
I think you are thinking of mutation of the BRCA genes, which is hereditary,
can be tested for and which confer an increased risk of breast cancer. Here
is a reference.
http://imaginis.com/breasthealth/brca.asp
As Ann T says ER+ is a characteristic of the tumour, not of the person.
What that means is that the cancer cells have significantly more than the
usual number of estrogen receptors, which is what ( or one of the things)
that makes them divide rapidly. In this respect each cancer is different,
even in the same patient.
Tim Jackson
bartalo@webtv.net - 14 Jan 2004 20:53 GMT
Thanks Ann and Tim for clarifying this for me. The BRCA genes test must
have been what I was confusing the ER+ with. Your url and that website
was especially helpful, Tim. I cannot believe that this time last year
if I had seen the initials "bc" it would have had a religious meaning
for me and today it means "breast cancer"! How quickly our lives do
change!
Bea