Taxol and the Tango Clinical Trials

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Mike - 14 Nov 2003 18:00 GMT

I have a friend who was recently diagnosed with breast cancer.
She is 36 and has been offered the Tango Clinical Trials with a
new drug called "Taxol".

However, she cannot find anything to assist her with making a
decision in respect of the benefits or risks involved. Much of
the advice she has received has been contradictory thereby adding
to the confusion.

If anyone could lead me to information (in layman's terms) about
the drug itself, the potential benefits and/or risks I would be
most grateful. Also, do professionals recommend the treatment and
if so why? Or is it simply another "maybe" that will be
understood after 5 years gathering "results"?

TIA.

Regards,
Mike.

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Tony Lima - 13 Nov 2003 23:45 GMT

>I have a friend who was recently diagnosed with breast cancer.
>She is 36 and has been offered the Tango Clinical Trials with a
[quoted text clipped - 10 lines]
>if so why? Or is it simply another "maybe" that will be
>understood after 5 years gathering "results"?

Mike, Taxol has been approved for use in the U.S. for about
ten years; it's not a new drug.

Can you give us some more details about the exact protocol
the "Tango" trial will be using? Drugs involved, dosages,
and the timing are all relevant. Thanks. - Tony

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Mike - 14 Nov 2003 23:51 GMT

Tony Lima wrote...

>>If anyone could lead me to information (in layman's terms) about
>>the drug itself, the potential benefits and/or risks I would be
[quoted text clipped - 8 lines]
>the "Tango" trial will be using? Drugs involved, dosages,
>and the timing are all relevant. Thanks. - Tony

I'll ask this and report back with as much info as possible. Give
me a few days please.

Thanks,
Mike

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Tony Lima - 15 Nov 2003 05:58 GMT

>I'll ask this and report back with as much info as possible. Give
>me a few days please.

Not necessary unless you want to. Tim's message provided
enough details for me! Best luck. - Tony

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Mike - 16 Nov 2003 09:53 GMT

Tony Lima wrote...

>>I'll ask this and report back with as much info as possible. Give
>>me a few days please.
>
>Not necessary unless you want to. Tim's message provided
>enough details for me! Best luck. - Tony

Ok, cheers.
Mike.

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A man - 14 Nov 2003 18:16 GMT

Did you search FDA.gov or cancer.gov yet? Sounds like a
tamoxifen based drug.

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Laura Katz - 19 Nov 2003 04:35 GMT

> I have a friend who was recently diagnosed with breast cancer.
> She is 36 and has been offered the Tango Clinical Trials with a
> new drug called "Taxol".
>
>Hi Mike:

I was son taxol a few years ago. To my knowledge it is not a new drug
but one that has been used extensively especially for bc. Ask your
friend to take a little notebook or pad in her purse when going to the
oncologist. Tell her to jot down all questions she wishes to ask,
including this.

I know from experience that when I finally see the doctor, I forget what
I wanted to ask!!!

Laura K.*
I'm out of estrogen and I have a gun!

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SssynSmrt - 20 Nov 2003 21:44 GMT

Laura is correct. Taxol has been around for a while - about 20 years or so, I
think. It was originally derived from the bark of the Pacific Yew tree.
States in the NW had a terrible time with poachers stripping bark from the Yews
in public and private forests until drug companies were able to synthesize the
active ingredients in Taxol.

Taxotere is derived from the bark of the European Yew tree.

I suspect that Mike's friend is undergoing a different set of protocols during
the trial. Maybe more Taxol treatments, treatments closer together, or a
combination of chemicals.

Sassy

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