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Medical Forum / Diseases and Disorders / Breast Cancer / August 2007Wife's Diagnosis
My Wife had Breast Cancer 10 years ago and it just came back in the same breast so she had both breasts just removed this past week. In the one Lymph Node the surgeon took out they found a 1.8 millimeter cancer tumor and the doctors are deciding about Chemo or not. The node that was removed was 1 cm in size and inside was the 1.8 millimeter cancer. Has anyone here had a simialr situation? The 1.8 millimeter size seems so tiny that she hopes that due to her lupus that she will not need Chemo. Thanks for any input. Louie > My Wife had Breast Cancer 10 years ago and it just came back in the > same breast so she had both breasts just removed this past week. In the [quoted text clipped - 8 lines] > > Louie What's her age please, Louie? I am crossposting, to another newsgroup, for potentiol questions and/or input from a clinical oncologist. J Her age is 59 ... thank you for your input Louie There is a new test being done to help determine http://www.genomichealth.com/oncotype/default.aspx Also I would make sure that you wife is being assessed at a Breast Cancer Center. Best of luck. Alex > There is a new test being done to help determine > > http://www.genomichealth.com/oncotype/default.aspx The trial doesn't fit Louie's wife One lymph node was positive and he hasn't mentioned hormone receptor status. J http://www.genomichealth.com/oncotype/tailorx/eligible.aspx The TAILORx trial is for women with recently diagnosed, early-stage (Stage I or II) breast cancer. The cancer must be: * Estrogen receptor-positive and/or progesterone receptor-positive * HER2/neu negative * Lymph node negative * At least 1 cm in size http://clinicaltrials.gov/ct/show/NCT00310180 This randomized phase III trial is trying to find out the best individual therapy for women who have node-negative, estrogen-receptor positive breast cancer by using a special test (Oncotype DX), and whether hormone therapy alone or hormone therapy together with combination chemotherapy is better for women who have an Oncotype DX recurrence score of 11-25. ______________________________________ J > There is a new test being done to help determine > > http://www.genomichealth.com/oncotype/default.aspx http://content.nejm.org/cgi/content/extract/353/12/1300 To the Editor: The use of the Oncotype DX assay in the study reported by Paik et al. (Dec. 30 issue)1 is an example of a conflict of interest. Most of the authors of the report are employed by, receive consulting fees from, or hold equity positions or stock options in Genomic Health, the manufacturer of Oncotype DX. These authors support the adoption of a $3,000 test in lieu of information already contained in a standard surgical pathology report the tumor grade. Table 1 of their article shows risk categories as determined by the Oncotype DX assay and the . . . [Full Text of this Article (needs signin to read the rest] J On which newsgroup would you post a question for a clinical oncologist? > On which newsgroup would you post a question for a clinical oncologist? usually sci.med.diseases.cancer Jeff J > My Wife had Breast Cancer 10 years ago and it just came back in the > same breast so she had both breasts just removed this past week. In the [quoted text clipped - 8 lines] > > Louie Louie, After rethinking your question, if having lupus was effective against cancer, she would not have gotten a recurrence. Boosting the immune system is sometimes helpful with melanoma or kidney cancer but not with epithelial type cancers. I would suggest that you draw up 4 pages : 1) pros of having 4 - 6 treatments of chemo 2) cons of having 4 -6 treatments of chemo, such as would it worsen her fatigue and how to help that OR such as her brain fog, if applicable (and to help that, and whether it might be permanent) or child bearing issues, if applicable 3) worst case scenario given her Lupus; which part of her body has been harmed by Lupus and might be at risk. 4) which treatments has she had before for Lupus; such as steroids and whether steroids would be required with the chemo and what effect that might have on her current bone situation. Then ask for more input (for each page) from the oncologist and discuss these all with the oncologist and make a decision from there. Best,. J |
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