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Medical Forum / Diseases and Disorders / Breast Cancer / July 2006

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mom's cancer - info needed

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judamd@aol.com - 26 Jul 2006 16:02 GMT
I've been a member of the prostate cancer newsgroup for a few years and
they have been a valuable tool for me in my battle against that
disease.  Now, I need your help with my mother's breast cancer.

My mother developed breast cancer twelve years ago at age 75.  If I
recall correctly, the pathology report after biopsy read "In situ,
ductile cell carcinoma" or something very similar.  She had a partial
mastectomy, there was some cancer in two lymph nodes, and she went on
to have radiation treatment.  She then spent five years on tamoxafin
(sp?).  A couple of days ago, her most recent mammogram showed calcium
deposits in one breast, the very same indicator that prompted the
biopsy twelve years ago and she is now scheduled for a biopsy.  My
questions may be premature since the biopsy has not yet been performed
but I'll ask a few of them anyway.

First, if this is a recurrence of the original cancer, I would assume
it is not going to be affected by tamoxafin this time since the drug
obviously didn't kill it off the first time.  Is that correct?

Secondly, with prostate cancer, a recurrence beyond ten years is
usually a new cancer that develops in residual prostate tissue left
behind in the original surgery.  Is this true with breast cancer too?

Third, my mom has lost about 20 pounds for no reason within the last
ten months or so, now down to less than 100 pounds.  Is this an
indicator of something more serious with the breast cancer?  Except for
osteoporosis, she seems to be in good health.

I have more questions but I'll save them for after the biopsy results
are in.  Hopefully I will not need to ask them.  Thanks for your time.
Dave Perry
Tim Jackson - 26 Jul 2006 16:48 GMT
> I've been a member of the prostate cancer newsgroup for a few years and
> they have been a valuable tool for me in my battle against that
[quoted text clipped - 14 lines]
> it is not going to be affected by tamoxafin this time since the drug
> obviously didn't kill it off the first time.  Is that correct?

I guess it has somewhat more chance of being ER- in this case than in
the population as a whole, but it doesn't have to be.  It could for
example be a completely new cancer that has developed since she went of
Tamoxifen.

> Secondly, with prostate cancer, a recurrence beyond ten years is
> usually a new cancer that develops in residual prostate tissue left
> behind in the original surgery.  Is this true with breast cancer too?

Not always, breast cancer can lie dormant for a long time, more so than
prostate.

> Third, my mom has lost about 20 pounds for no reason within the last
> ten months or so, now down to less than 100 pounds.  Is this an
> indicator of something more serious with the breast cancer?  Except for
> osteoporosis, she seems to be in good health.

It's possible.  A CAT scan might reveal any indications, if the biopsy
comes back positive.  On the other hand it is also possible that the
microcalcifications are actually associated with whatever is causing the
weight loss and not with cancer at all.  At 87 it would be unusual if
there weren't a few (age-related) things going on that would cause some
changes.

> I have more questions but I'll save them for after the biopsy results
> are in.  Hopefully I will not need to ask them.  Thanks for your time.
> Dave Perry

Fingers crossed for her.

Tim Jackson
 
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