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Medical Forum / Diseases and Disorders / Breast Cancer / November 2005

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and another thing

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Martin Bell - 11 Nov 2005 17:52 GMT
Here's another thing. No, don't go away!
Krebs et al in "The Unitarian or Trophoblastic thesis of Cancer' state that
no "experimentally established datum (has been produced) that would
controvert the thesis of the basic biological uniformity characterising all
exhibitions of cancer"
So why do oncologists seem so keen to labour the opposite point? The old
cliche "Cancer is not one disease but many is cranked out by solemnly
intoning  specialists to reinforce the notion that the condition is
immensely complex and arcane and that only such as they could possibly come
close to understanding its many manifestations. Obfuscation in, perhaps,
their own professional interests?
One day the experts might entertain the possibility that cancer is,after
all, one disease (albeit with the capacity to appear in  different
locations/tissues according to local factors) with just one underlying
cause. I mean, what are the odds that all these hundreds of so-called
'carcinogenic' substances  having the one identical effect on a cell's
behaviour (ie proliferation)?
Gabriel - 11 Nov 2005 18:26 GMT
> Krebs et al in "The Unitarian or Trophoblastic thesis of Cancer' state that
> no "experimentally established datum (has been produced) that would
> controvert the thesis of the basic biological uniformity characterising all
> exhibitions of cancer"
> So why do oncologists...

At the time of writing, this is the only message in this thread. Am I
being cynical in expecting a posting pointing out cancer cures based on
the unitarian theory which are available for purchase?
Tim Jackson - 11 Nov 2005 18:31 GMT
> Here's another thing. No, don't go away!
> Krebs et al in "The Unitarian or Trophoblastic thesis of Cancer' state that
[quoted text clipped - 13 lines]
> 'carcinogenic' substances  having the one identical effect on a cell's
> behaviour (ie proliferation)?

On reason is that it is well established that some cancers, even of the
same tissue, will respond readily to a particular drug, while others
seemingly similar, do not.

Clearly there is some biological commonality between different cancers,
but it is also clear that there are some considerable differences eg in
expressed proteins, and I cannot accept that there is no evidence that
there are different forms.  Are you suggesting that the routine test
results for estrogen receptors, growth factor receptors etc, which are
statistically proven to relate to the effectiveness of corresponding
therapies, are meaningless?

It seems to me that the theory that there are many different forms of
cancer comes mostly from microbiologists researching the underlying
mechanism, not from medical oncologists who are more concerned with the
pragmatic solutions of "what works".

Tim Jackson
 
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