Re: Janet Dx 10/02, her2+, lumpectomy, node -ve, herceptin + taxotere +
carboplatin, + radiation + tamoxifen, now arimidex + zoladex.
Hi,
Havent been here for a while, mainly due to Janet being mainly fine,
along with a few PC problems making it difficult to connect for periods.
Anyway, just had 2 year anniversary and oncologist has changed Janet
from Tamoxifen to Arimidex + monthly Zoladex.
Janet doesnt like the idea of a Zoladex injection every month for 5
years, and has been given the option of having her ovaries removed.
She has asked me to ask if there is much evidence of people taking
Zoladex for 5 years, and what are the side effects after that time?
Also, what are peoples thoughts of Zoladex for 5 years, or removal of
ovaries?
Many thanks.

Signature
Richard Faulkner
Kaye301 - 30 Dec 2004 15:30 GMT
<< Also, what are peoples thoughts of Zoladex for 5 years, or removal of
ovaries? >>\
Hi Richard, that's a tough one. How old is Janet? My gut level reaction
would be to remove the ovaries, but I am not a researcher nor a physician.
There is 'new' information coming out periodically about what is 'best' or
optimal in this regard. My suggestion would be to get a few second opinions if
possible, from both experienced or well-seasoned oncologists, as well as at a
major cancer center.
I was also Her2+ as well as ER+ In addition one of the types of bc I had was
lobular which has a greater likelihood of metastasizing to pelvic areas. After
much research, along with symptoms and other signs that warranted intervention,
I chose a complete abdominal hysterectomy and Salpingo--oopherectomy. For me,
it was a 'piece of cake.' I did this 18 mos. after a bilateral mastectomy.
The reason I went with the complete surgery was that there was new info coming
out that for those with a family hx of b.c. that overall survival was
improved. Since that is my goal, I went ahead and did that.
In addition I also checked out different procedures. I was fortunate to have
had my surgery done by a top gynocological oncologist. In fact before the
final decision, I asked him what he would recommend for his wife or mother--and
he said the same.
I chose the abdominal procedure as opposed to the laparoscopic or vaginal
procedure because I had read that there cancer cells have been found along the
path of the laparoscope. Since the reason I was doing it was to reduce my risk
of recurrence I wanted to do what would maximize the effectiveness.
I am not sure if I did so well during the surgery because I was in such good
shape (worked out at the gym regularly) or because of the surgeon's skills.
Originally he had told me that the laparoscopic or vaginal procedure was easier
on me but harder on him and that my hospital stay would be 2 to 3 nights if I
did that. If I did the abdominal surgery my stay would be 3 to 4 nights. I
did so well with the abdominal surgery that he said I could go home after 2
nights! However, I opted to stay a 3rd night just in case.
One thing that helped with the surgery was having Zofran mixed in with the
anesthesia. When I awoke in recovery I didn't experience that awful, yucky
feeling that one often has as they come out of the anesthesia.
Recovery was also fairly quick. I was back at the gym, riding the exercycle,
two weeks to the day after the surgery.
Before the surgery I had asked what kinds of hormonal side effects I would
have. I had read about those being quite strong. However, he told me that I
would not experience anything more than I had already been having from
'chemopause.' He was right. The hot flashes did not get signficantly worse.
There may have been a few more at first but nothing that bad. Anyway, that
was my experience.
My best thougts are with Janet and again would recommend 2nd opinion(s).