Hello,
the cold has a "vasoconstrictor" effect, and shoud prevent the active
elements of the chemo to reach the  hair cells.
there should be no risk for the brain, but  yes,  you  prevent the chemo to
reach the  hair and it should therefore prevent hair loss. But  you do not
avoid the risk of mets in that region.
But as the doctors somehow said, "when you have mets in the lungs, liver,
kidneys, bones (etc?), you do not worry  about some more mets on your skull
cap".

And  my wife ( you should know how beautifull she is ) was about to refuse
the  new chemo  if it should cause hair loss. And this is normally  a fact
with Taxol.
And I  understand she clings to her dignity, and she hated it to lose her
hair  the first time. She  would rather!

But my question  still is : what is the best  way to prevent the pain
caused by this ice cap.

Thank you.

Ps  Is this an urgent  question? We went to  the hospital yesterday for her
third  chemo session with Taxol, but were sent home, because she was to weak
( too low red  "globules" count), and have a new apointment fot next week.
Meanwhile she got a  injection of EPO, and although she  might not go to the
Olympics because of that,  she seems to be reacting  well already.
Have a good WE.

and thanks  for any answer.

Jean.