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Medical Forum / Diseases and Disorders / Asthma / September 2004

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Albuterol revisited

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jrp32a@yahoo.spam - 15 Sep 2004 18:31 GMT
Just read the thread started on 9/10 concerning Albuterol.

To put it as short as i can, the very first time I used albuterol I
experienced near instantaneous miraculous relief that lasted many hours.
Possibly because i had been pretty much suffocating in place for days the
sudden relief was so dramatic.
Never since have I achieved that kind of relief with it, but then my
respiration has not gotten as bad either.  I recently have been using one
3 ml vial every 6 days -- stretching it by cutting it with water.   I
believe there is a certain psychological component in using the nebulizer.

Does anyone dispute that a physical tolerance is developed for this drug?

jim
AquillatheHun - 19 Sep 2004 13:56 GMT
> Just read the thread started on 9/10 concerning Albuterol.
>
[quoted text clipped - 10 lines]
>
> jim

From what I know, cutting with water can be very dangerous, unless its a
sterile saline solution.
Never use tap water, it has way too many microorganisms and they can get
into your lungs and make matters worse.
jrp32a@yahoo.spam - 19 Sep 2004 15:07 GMT
>From what I know, cutting with water can be very dangerous, unless its a
>sterile saline solution.
>Never use tap water, it has way too many microorganisms and they can get
>into your lungs and make matters worse.

Thank you.

FACE
jrp32a@yahoo.spam - 19 Sep 2004 15:08 GMT
>From what I know, cutting with water can be very dangerous, unless its a
>sterile saline solution.
>Never use tap water, it has way too many microorganisms and they can get
>into your lungs and make matters worse.

Thank you.

Jim
iamthezookeeper - 19 Sep 2004 22:09 GMT
Hi all...newbie to this board...I am over at Sinusitis most of the time and
on a Samter's Triad Board on Yahoo. I have been using Albuterol Inhalers
and in my Nebulizer for 23 years and never found I developed a tolerance.
I will agree with the posts about not cutting your dose with H2o. If
anything I would ask the doctor if you can use a vial of sterile saline to
cut it with though the correct dosage is what makes your lungs clear out.
jrp32a@yahoo.spam - 20 Sep 2004 16:52 GMT
>Hi all...newbie to this board...I am over at Sinusitis most of the time and
>on a Samter's Triad Board on Yahoo. I have been using Albuterol Inhalers
>and in my Nebulizer for 23 years and never found I developed a tolerance.
>I will agree with the posts about not cutting your dose with H2o. If
>anything I would ask the doctor if you can use a vial of sterile saline to
>cut it with though the correct dosage is what makes your lungs clear out.

I agree down the line and thank you for the response and personal
experience.  Personal experience is often unique to the individual but has a
tendency to out weigh the theoretical.

My thoughts on the H2O is that we live in anything but a septic world as it
is and a lot of less than desirable stuff is taken into the lungs through
normal respiration and just living -- not to say that more stuff should be
introduced.

Jim
jackmallory@webtv.net - 23 Sep 2004 06:09 GMT
Those three ml vials have a lot of albuterol in 'em, Jim.  Just compare
the numbers with what you get in two puffs on an albuterol MDI.

I cut way back  on the nebulized albuterol when my pulse started racing:
it was interfering with my pulmonary rehab sessions.

Haven't  been diluting.  What I do is count the number of inhalations: a
dozen or so by mouth and a dozen up the nose, which I find just great
for sinus conjestion.
Maybe a little more  in the morning.  (Enough for relief of course.)

BTW my first experience with albuterol some ten years ago was like
yours:  it seemed like a miracle!  On the other hand I can't say my
general responce to the drug has diminished in all that time.---Jack


jrp32a@yahoo.spam - 26 Sep 2004 14:21 GMT
We have similar thoughts and experiences.

I usually find that I can get by with 6-7 "breaths in" twice a day or from
10-12 "breaths in" to as much as 1 1/2 - 2 minute treatment (by the clock)
if i am needing it.  Agreed on whatever is necessary for relief and of
course that differs per individual.

My wife does at least a vial a day, often 2, and is having problems with
blood pressure, heart rate and excitability.  She takes more pills for those
(and several others) and I kid her about taking pills on top of pills for
problems created by pills (or inhalations).

The thing is, she and I have both been in the literally "stumbling" out of
breath mode, but really haven't been for over a year....and i offered the
opinion last week that now, the least discomfort sends us running (huffing
and puffing) to the nebulizer.  It is on this basis that i cannot say
whether the efficacy of racemic albuterol for us has abated.  I still have
part of a box of 60 vials that I bought last May,  I did check the
expiration date and it is August, 2006 -- they are kept in the dark, at room
temperature.

I also agree on the sinus congestion.  The best thing I found in years for
that - by accident --  was Primatene mist, inhaled and then exhaled through
the nose.  I can't say that Primatene is that great as a bronchodilator
(Beta-agonist?) What it did was relieve my congestion without the
reingorgement of the stronger Afrin-type stuff.  (Course, after several
months, I got "used" to that and Primatene did not work the sinus miracle
anymore.)

I have wondered if the MDI might not be a higher percentage dose, but have
not read the micro-print recently. :-)

For those who have not heard this:  For us people, an all-nighter has come
to mean sleeping till dawn.

(for the septic crowd, note that the ingredients in your racemic albuterol
has a tiny percentage of sulfuric acid, for Xopenex the tiny percentage is
hydrochloric acid -- or maybe the two acids are the other way around.)

jim

>Those three ml vials have a lot of albuterol in 'em, Jim.  Just compare
>the numbers with what you get in two puffs on an albuterol MDI.
[quoted text clipped - 10 lines]
>yours:  it seemed like a miracle!  On the other hand I can't say my
>general responce to the drug has diminished in all that time.---Jack
 
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