> I still check in regularly but don't post often.
>
[quoted text clipped - 8 lines]
> Advair to the 500/50 inhaler and if he still wants to add steroid to that
> give an additional Flovent inhaler(also fluticasone)?
I was first started on the 500/50 advair, though at the time I was
prescribed the qvar three times a day and the advair only twice. I
hadn't thought of that til now actually, which makes me wonder if I
just add the afternoon dose of qvar if the breathing troubles would go
away again... *makes a note of it for next MD appointment*
> The manufacturer says you are not supposed to use the Advair more than 60
> days after removing it from the foil pouch (although I do it all the time)
> so there is some argument to adding and subtracting a steroid inhaler to a
> mid dose of Advair (like 250/50) if the increase is going to be for less
> than a month (rather than throwing out a perfectly good Advair inhaler).
Hrm, the advair I have says to not use after its been opened for 30
days, do you know whether this is because the stuff breaks down over
time and would no longer work? Not that my current inhaler's been open
any longer, just curious since you mentioned it.
> The other thing is that Qvar is a little cheaper than Flovent so it would be
> a cheaper addition. However, it would be cheapest to just go up to the
> 500/50 Advair if you are not taking it already. If you are it would be
> cheaper to take Serevent and high dose Qvar so I'm thinking the cost is not
> really the issue.
Cost is no issue at the moment, the county health plan I'm on has no
co-pay for medications prescribed by doctor that is on the "approved"
list, which both qvar and advair are.
> It would be interesting to know what your doctor says.
Thanks for your insight, I'll try to remember to post here what my doc
thinks of all this, when I see her in two months. Thankfully, I've not
had any asthma attacks away from home bad enough to make me run to the
doctor's just yet. And, at home, I have my wonderful nebulizer.
I'm now wondering if it isn't just that missing afternoon dose of
inhaler that's causing me problems. It is definitely mid-afternoon and
early evenings up to the night dose of advair that I'm having most
breathing problems. It was for that exact reason that my doctor
originally had the qvar dosage increased to three times a day, way
back when before I started taking the advair. But, advair can only be
taken twice a day, I was told.
Dragonfly
00doc - 16 Mar 2008 15:47 GMT
On Mar 15, 12:51 pm, "00doc" <00...@comcast.net> wrote:
> I still check in regularly but don't post often.
>
[quoted text clipped - 11 lines]
> > that
> > give an additional Flovent inhaler(also fluticasone)?
> I was first started on the 500/50 advair, though at the time I was
> prescribed the qvar three times a day and the advair only twice. I
> hadn't thought of that til now actually, which makes me wonder if I
> just add the afternoon dose of qvar if the breathing troubles would go
> away again... *makes a note of it for next MD appointment*
For most people the steroid can be given once or twice daily. It may be that
you just need more and could add the extra dose to the morning and/or
evening dose. On the other hand you might be unusual and really do better
with three doses daily. The only way to know is experiment.
> > The manufacturer says you are not supposed to use the Advair more than
> > 60
[quoted text clipped - 4 lines]
> > mid dose of Advair (like 250/50) if the increase is going to be for less
> > than a month (rather than throwing out a perfectly good Advair inhaler).
> Hrm, the advair I have says to not use after its been opened for 30
> days, do you know whether this is because the stuff breaks down over
> time and would no longer work? Not that my current inhaler's been open
> any longer, just curious since you mentioned it.
You are right - the package insert says to destroy it one month after
opening the foil pouch. As I said I use it intermittently and so sometimes
use ones that have been open a year or more. They seem to work just fine but
my asthma is currently mild enough that I am not sure I would notice a
decrease in effectiveness. Of course, if this is an aisue you could use the
MDI (traditional puffer) and presumably not have the same issue.
> > The other thing is that Qvar is a little cheaper than Flovent so it
> > would be
[quoted text clipped - 3 lines]
> > not
> > really the issue.
> Cost is no issue at the moment, the county health plan I'm on has no
> co-pay for medications prescribed by doctor that is on the "approved"
> list, which both qvar and advair are.
That is a large part of the problem with the American healthcare system.
People think they are not paying if they do not exchange cash at the
register. You are paying for it one way or another - whether it be cash,
more taxes, lower wages, or fewer government benefits. It would be cheaper
and more flexible to give Serevent and then a Qvar inhaler and adjust the
steroid dose as needed.
> > It would be interesting to know what your doctor says.
> Thanks for your insight, I'll try to remember to post here what my doc
> thinks of all this, when I see her in two months. That would be
> interesting.
There was a study a while back using an inhaler that contained a combination
of albuterol and steroid just as needed vs. a traditional regimen. They
found better control with lower total steroid doses presumably because the
steroids were always titrated to an exact match with the symptoms/albuterol
use. Unfortunately, that inhaler is not available but the results could be
mimiced. One way would be to give the Advair 500/50 and then every day have
you take a number of puffs of Qvar to equal the previous day's albuterol use
(divided twice or three times daily).
Alternatively, for some people using Symbicort as needed may be reasonable
(but completely and totally off label). Symbicort is a different long acting
dilator and steroid combination but the dilator has a faster onset that some
people think is fast enough to use as a rescue inhaler (but not all people
and not the FDA). Of course, if your doc was not willing to go off label
like this (s)he would not be giving the Advair/Qvar combo as you are doing.
It would probably not be reasonable for people with a history of sudden
severe attacks. The dose of long acting dilator might get to be excessive
this way (and would often exceed the recommended doses) but another inhaled
steroid could be added at that point. I suspect Symbicort may not be on your
formulary. It is not listed as much more expensive as Advair but they don't
seem to make deals as aggressively as the Advair people do.
Other options would be to add Singulair (probably not on formulary - it
usually isn't) or Accolate (better chance to be on formulary). Theophylline
may also be useful in low doses to keep the dose of steroid down. Short
bursts of oral prednisone as needed for flares is also good for some people.
If your problems are mostly at night you may want to consider allergies
(dust mites?- add nasal steroids?- something else at home?) and reflux as
triggers.

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