> Supposedly the new propellent is supposed to save the ecology, but it's
> worthless for saving anyone's life who has a serious asthma attack. My
> doctor tells me that many of his patients have the same complaint. Why a
> change in propellant should change the efficacy of Albuterol is beyond
> me. I'll bet the damn drug companies changed more than just the
> propellant.
Funny,
Up here in Canada, we're had the HFA one for a lot longer than most in
the US. I've noticed no such change in the efficacy of the drug.
Michael Halliwell
Julie C - 27 Jan 2008 15:34 GMT
>> Supposedly the new propellent is supposed to save the ecology, but it's
>> worthless for saving anyone's life who has a serious asthma attack. My
[quoted text clipped - 9 lines]
>
> Michael Halliwell
I'm in the US and just received my first one and I like it better.
Julie C
miles - 28 Jan 2008 13:17 GMT
> Up here in Canada, we're had the HFA one for a lot longer than most in
> the US. I've noticed no such change in the efficacy of the drug.
When did HFA appear in Canada? It's been around for many years in the
USA. It's just recently in the past year or so that the older non-HFA
is no longer available. Used to be able to get either one.
M. Halliwell - 29 Jan 2008 03:02 GMT
>> Up here in Canada, we're had the HFA one for a lot longer than most in
>> the US. I've noticed no such change in the efficacy of the drug.
>
> When did HFA appear in Canada? It's been around for many years in the
> USA. It's just recently in the past year or so that the older non-HFA
> is no longer available. Used to be able to get either one.
It's been a few years (4?). There was no phase out of the CFC
propellant ones...basically one refill it was CFC only, then next it was
HFA only.
I guess part of the issue is that the transition / phase out period has
ended in the US and people don't like that they can't get the old CFC
ones any more.
Michael
miles - 30 Jan 2008 00:41 GMT
> I guess part of the issue is that the transition / phase out period has
> ended in the US and people don't like that they can't get the old CFC
> ones any more.
Biggest issue for me is the laws regarding generic drugs. Generally
generic drugs can only be made by any company that wants too after 7
years from release of the name brand. So when CFC's went away so did
the generic Albuterol inhalers. My $6 prescription now costs me about
$28. In another 5 years or so generic HFA's will be allowed and the
price will drop.
M. Halliwell - 30 Jan 2008 07:24 GMT
>> I guess part of the issue is that the transition / phase out period
>> has ended in the US and people don't like that they can't get the old
[quoted text clipped - 6 lines]
> $28. In another 5 years or so generic HFA's will be allowed and the
> price will drop.
I'm surprised at this...the medication hasn't changed, nor has the
method...only the propellant in that method. Seems to me like that is a
dang broad brush if the patent laws for drugs apply to the delivery too,
not just the medicinal ingredients.
I guess in the US you'll need to make sure Pfizer, GSK and so forth
don't start using hybrid-electrics to deliver their meds to
stores...otherwise Al Gore could be in for 7 years of bad luck ;)
Michael
00doc - 02 Feb 2008 18:31 GMT
> Biggest issue for me is the laws regarding generic drugs. Generally
> generic drugs can only be made by any company that wants too after 7 years
> from release of the name brand.
Wrong on both counts.
The patents last for 20 years from the time of filing with the FDA. It
typically takes several years for the patent to be approved (not uncommonly
as long as 8 years) and this time comes out of the life of the patent. Some
say this does not make sense and is unfair but it is consistent with the
rest of US patent law (all patents date from the filing - not the granting)
and it prevents drug companies from filing minimalist applications
initially - i.e it encourages them to do all the studies that might be
required before submitting the application since requests for further
studies/information hurts them considerably.

Signature
00doc
miles - 04 Feb 2008 02:20 GMT
> The patents last for 20 years from the time of filing with the FDA.
Then the patent for HFA Albuterol inhalers must have been 15 years ago.
You will see generics out in 4 or 5 years, 2 to 3 years after they
appeared on shelves.
00doc - 04 Feb 2008 13:09 GMT
>> The patents last for 20 years from the time of filing with the FDA.
>
> Then the patent for HFA Albuterol inhalers must have been 15 years ago.
> You will see generics out in 4 or 5 years, 2 to 3 years after they
> appeared on shelves.
The patents expire in 2010. They often stave off the indroduction of
generics for a while with court challenges so I would not count ona generic
hitting the market immediately. Also, the first generic has 6 months of
exclusivity and so usually does not bring the prices down all that much. I
wouldn't expect significant price drops for cash paying people until 2011 or
2012 although people with insurance may get to go back to the generic co-pay
in 2010 or 2011.
Proventil HFA was FDA approved in 1996 or 1999 - I have conflicting
information.

Signature
00doc
erach27@gmail.com - 17 Feb 2008 11:35 GMT
Please check out "urine therapy" 136,000 web-pages where you drink/use
your own pee/urine to cure ALL illnesses including genetic ones and
AIDS/cancer/.
Also check out http://www.geocities.com/erach27/spacetimemotion.htm
Erach
> >> The patents last for 20 years from the time of filing with the FDA.
>
[quoted text clipped - 15 lines]
> --
> 00doc
Please check out "urine therapy" 136,000 web-pages where you drink/use
your own pee/urine to cure ALL illnesses including genetic ones and
AIDS/cancer/.
Also check out http://www.geocities.com/erach27/spacetimemotion.htm
Erach