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Medical Forum / Diseases and Disorders / Asthma / October 2003

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New study on melatonin and asthma

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Richard Friedel - 18 Oct 2003 07:41 GMT
http://www.nationaljewish.org/news/melatonin.html

"People with asthma should consider limiting the use of melatonin as a
sleep aid,  according to researchers at National Jewish Medical and
Research Center.  Pulmonologist Rand Sutherland, M.D., M.P.H., and his
colleagues report in the  September 2003 issue of the Journal of Allergy
and Clinical Immunology that  higher levels of melatonin were associated
with an overnight loss of lung function  in asthma patients. Previous
studies by the same group have shown that  melatonin induces the release
of chemicals that promote inflammation, a hallmark  symptom of asthma."
Arrhae - 19 Oct 2003 21:53 GMT
On 10/18/03 2:41 AM, in article 3F90E08A.C92F0134@mailin.lrz-muenchen.de,

> http://www.nationaljewish.org/news/melatonin.html
>
[quoted text clipped - 6 lines]
> studies by the same group have shown that  melatonin induces the release
> of chemicals that promote inflammation, a hallmark  symptom of asthma."

Hmmm.  I have SAD, which is apparently caused by more melatonin production
when there's less light...
Immuno - 20 Oct 2003 09:04 GMT
> http://www.nationaljewish.org/news/melatonin.html
>
[quoted text clipped - 6 lines]
> studies by the same group have shown that  melatonin induces the release
> of chemicals that promote inflammation, a hallmark  symptom of asthma."

One kind of wonders where the research this group is performing is leading?

Clearly melatonin, in the eyes of this group, is a "bad thing". What can we
poor unfortunate asthmatics do to prevent its corrosive effects on our
lives - one asks ones self.

Never turn out the lights when we go to bed! Simple! Next question.........

Pete
[yes, written in sarcasm mode]
Richard Friedel - 20 Oct 2003 12:35 GMT
> > http://www.nationaljewish.org/news/melatonin.html
> >
[quoted text clipped - 17 lines]
> Pete
> [yes, written in sarcasm mode]

Well I do definitely have the urge to sermonize about this sort of
thing!

I was for ages a true-believer in asthma drugs. Then I happened to hit
upon a tactic for defusing the whole thing.  I managed to curb attacks.

See Professor D. Hillsman
(http://www.ohiou.edu/isarp/conf_02/papr_4.htm) on prolonging the exhale
for COPD but also with some emphasis on asthma:

"The commonest and usually best deflation strategy is a non-forced, or
minimally forced, prolongation of the expiratory time by approximately
25%. This will minimize the problem of Dynamic Bronchial Compression
(DBC) as discussed below.

Repeated over several breaths all Dynamic Hyperinflation should be
corrected, and the patient comfortable within 10 or so breaths."

In other words it is possible to nip an attack in the bud by diligently
prolonging the exhale.

It may take a year or so of practice before you can go around without
asthma medication but I think it is very worthwhile trying.  Probably
you'd always have the medication with you, even you felt you were
completely out of trouble.

Its your choice I guess, can you really blame others?  Respectfully,
Richard Friedel
Colin Campbell - 20 Oct 2003 16:31 GMT
>I was for ages a true-believer in asthma drugs. Then I happened to hit
>upon a tactic for defusing the whole thing.  I managed to curb attacks.

And now you are a 'true believer' in a patent remedy.

--
There can be no triumph without loss.
No victory without suffering.
No freedom without sacrifice.
Richard Friedel - 20 Oct 2003 18:47 GMT
> >I was for ages a true-believer in asthma drugs. Then I happened to hit
> >upon a tactic for defusing the whole thing.  I managed to curb attacks.
[quoted text clipped - 5 lines]
> No victory without suffering.
> No freedom without sacrifice.

Seeing that asthma drugs are patented, this sounds a bit strange.
Professor D. Hillsman has come along with this effective tactic for
curbing attacks and defusing asthma. Have you any problems with it?
Colin Campbell - 20 Oct 2003 21:03 GMT
>Seeing that asthma drugs are patented, this sounds a bit strange.
>Professor D. Hillsman has come along with this effective tactic for
>curbing attacks and defusing asthma. Have you any problems with it?

I am not convinced and feel that this doctor is premature in his
conclusions.  

--
There can be no triumph without loss.
No victory without suffering.
No freedom without sacrifice.
Immuno - 20 Oct 2003 18:31 GMT
<snipped>

> Its your choice I guess, can you really blame others?  Respectfully,
> Richard Friedel

I know my reply was sarcastic - but it did relate to your original post.

Just what does your follow-up have to do with my reply, or even melatonin
and asthma?

Pete
Richard Friedel - 20 Oct 2003 18:46 GMT
<snipped>

> Its your choice I guess, can you really blame others?  Respectfully,
> Richard Friedel

I know my reply was sarcastic - but it did relate to your original post.

Just what does your follow-up have to do with my reply, or even
melatonin
and asthma?

Pete

I was trying to talk you out of what seemed like self-pity, or were you
being ironical with "poor asthmatics"?
Immuno - 21 Oct 2003 09:34 GMT
> <snipped>
> >
[quoted text clipped - 11 lines]
> I was trying to talk you out of what seemed like self-pity, or were you
> being ironical with "poor asthmatics"?

To clarify - yes to sarcasm and YES to irony!

I've not had an opportunity to read the full paper yet - however, from the
abstract, I see that the group has shown "melatonin induces the release of
chemicals that promote inflammation, a hallmark  symptom of asthma" IN
ITRO  - a small and trivial (sarcasm) detail omitted from the item you
quoted. Despite what the "bunny huggers" would have one believe in-vitro is
a long way from in-vivo.

Furthermore, as I said in my original reply - I wonder where this "research"
is going. The next logical step would be (for some idiot) to suggest that
asthmatics take melatonin antagonists. I suggest you try searches on
melatonin and schizophrenia/sleep disorders/seasonal affective disorder/jet
lag/reproduction......................... oh and circadian rhythms too :o)

I, for one, am not about to screw-around with the workings of my anterior
pituitary.

Pete
ARoberts - 21 Oct 2003 10:58 GMT
> > <snipped>
> > >
[quoted text clipped - 31 lines]
>
> Pete

Are you saying that you don't wish to test the hypophysis?  ;-)
Immuno - 21 Oct 2003 15:25 GMT
<snip>
> > I, for one, am not about to screw-around with the workings of my anterior
> > pituitary.
> >
> > Pete
>
> Are you saying that you don't wish to test the hypophysis?  ;-)

Very droll :o).....
Richard Friedel - 21 Oct 2003 14:54 GMT
> > <snipped>
> > >
[quoted text clipped - 31 lines]
>
> Pete

Hi Pete,

I originally thought the item might be of general interest.  The pointer
to it came from the scientific section of a national newspaper.
PENMART01 - 21 Oct 2003 16:04 GMT
>ImmunoPigFeces wrote:
>> > >
[quoted text clipped - 12 lines]
>I originally thought the item might be of general interest.  The pointer
>to it came from the scientific section of a national newspaper.

Which, "The Hillybilly Hayseed"?  With your kinda purpetual ignorant claptrap
you'd be a fine candidate for the "Asthma is a Mental Disease" poster boy... of
course you'd incur plenty of competition from the rest of your asa mental
midget cohorts.

---= BOYCOTT FRENCH--GERMAN (belgium) =---
     ---= Move UNITED NATIONS To Paris =---
Sheldon          
````````````
"Life would be devoid of all meaning were it without tribulation."
     
Richard Friedel - 21 Oct 2003 21:04 GMT
.........
> >I originally thought the item might be of general interest.  The pointer
> >to it came from the scientific section of a national newspaper.
[quoted text clipped - 9 lines]
> ````````````
> "Life would be devoid of all meaning were it without tribulation."

The point I'm usually trying to make is that there might be a lot less
asthma around if more people practised breathing exercises - like pursed
lips breathing. An attempt is needed to defuse asthma, not
fear-mongering. Do we really want all athletes to be doped asthmatics
some day? Richard Friedel
PENMART01 - 21 Oct 2003 21:30 GMT
>.........
>> >I originally thought the item might be of general interest.  The pointer
[quoted text clipped - 8 lines]
>>
>The point I'm <S> usually </S> trying to make is that there might be a lot
less
>asthma around if more people practised breathing exercises - like pursed
>lips breathing.

Chicanery.  

Imbecile!  

Smarmy piece of sh.t... usually.  

You dumb bastard.

---= BOYCOTT FRENCH--GERMAN (belgium) =---
     ---= Move UNITED NATIONS To Paris =---
Sheldon          
````````````
"Life would be devoid of all meaning were it without tribulation."
     
Bob - 23 Oct 2003 01:20 GMT
>Imbecile!  
>
>Smarmy piece of sh.t... usually.  
>
>You dumb bastard.

What a brilliant reflection.
http://www.3rdeyeguidance.com/Mirror/welcome.html

>---= BOYCOTT FRENCH--GERMAN (belgium) =---
>      ---= Move UNITED NATIONS To Paris =---
>Sheldon          
>````````````
>"Life would be devoid of all meaning were it without tribulation."
   
Arrhae - 22 Oct 2003 05:05 GMT
> Which, "The Hillybilly Hayseed"?  With your kinda purpetual ignorant claptrap
> you'd be a fine candidate for the "Asthma is a Mental Disease" poster boy...
> of
> course you'd incur plenty of competition from the rest of your asa mental
> midget cohorts.

My mother is claiming that asthma is caused by stress, so basically it's all
in my head and I guess she's trying to say I should stop taking my meds, as
I haven't died yet without them, despite the fact that if I'm not on them
I've got virtually no endurance, never have, and even when as in shape as I
get, would be beaten by a 400 lb person running across a parking lot for
Krispy Kremes...
Colin Campbell - 22 Oct 2003 06:29 GMT
>My mother is claiming that asthma is caused by stress, so basically it's all
>in my head and I guess she's trying to say I should stop taking my meds, as
>I haven't died yet without them, despite the fact that if I'm not on them
>I've got virtually no endurance, never have, and even when as in shape as I
>get, would be beaten by a 400 lb person running across a parking lot for
>Krispy Kremes...

Just smile tolerantly at her and ignore what she says.  Some people
are immune to facts and it is just not worth trying to teach them.

--
There can be no triumph without loss.
No victory without suffering.
No freedom without sacrifice.
jackmallory@webtv.net - 22 Oct 2003 23:26 GMT
Hypophysis?  What ironly.
 
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