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Medical Forum / Diseases and Disorders / Asthma / August 2006

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inhaled steroid and oral steroid

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toypup - 01 Aug 2006 21:31 GMT
Is it necessary to stay on inhaled steroids while on oral steroids?  There
is one docotor who says it takes two weeks for Qvar to start working, so
take both Qvar and Medrol at the same time to build Qvar up while Medrol is
working.  She always has her hospitalized patients take both.  There is the
other doctor who says Medrol is flooding the system with steroids, so there
is no need to take Qvar while on Medrol, because the steroid levels are
boosted up and the amount of steroid from Qvar is so minimal in comparison.
He restarts his hospitalized patients on Qvar after being done with Medrol.
SJF - 01 Aug 2006 23:05 GMT
> Is it necessary to stay on inhaled steroids while on oral steroids?  There
> is one docotor who says it takes two weeks for Qvar to start working, so
[quoted text clipped - 5 lines]
> comparison. He restarts his hospitalized patients on Qvar after being done
> with Medrol.

Hopefully, you will get professional comment on your question.  But I will
provide this comment from a long-time asthmatic who has the necessary meds
on hand to manage flare-ups on his own.

I depend on the inhaled steroids for routine control of asthma.
Occasionally, this control has not sufficed and I used oral steroids as a
*supplement*.  As soon as I could, I tapered off the oral.

High dosing with oral steroid requires an often problematic transition
period.  It seems to me that this transition is much easier to manage if you
maintain the inhaled steroid at the accustomed level.

Several years ago, my dosage of the inhaled steroid was increased (from
Advair100/50 to Advair 250/50) and I have not since needed the oral
steroids.

SJF
00doc - 02 Aug 2006 00:52 GMT
> Is it necessary to stay on inhaled steroids while on oral steroids?  There
> is one docotor who says it takes two weeks for Qvar to start working, so
[quoted text clipped - 5 lines]
> comparison. He restarts his hospitalized patients on Qvar after being done
> with Medrol.

They both have a point. The oral steorids are giving amuch larger dose than
the inhaled steroids so the inhaled steroids are probably not adding much.
However, in studies done in ED's of giving a prescription for an inhaled
steroid along with the oral steroids has been shown to prevent return trips
to the ED.  Often it is easier to just continue the steroids rather than try
to explain when to stop and restart them. Many patients will just stop the
inhaled steroid and then never restart it.

I think it is probably a bit of a tempest in a teapot to argue about it. The
important thing is that there should not be a gap between the oral steroids
and restarting the inhaled steroid.

The two weeks part is a bit off. It might take a bit to see the full effect
if you take a poorly controlled asthmatic and just start an inhaled steroid.
However, if a course of oral steroids is given that should jump start the
whole thing and allow the inhaled steroid start from a position of already
being "kicked in".

Signature

00doc

toypup - 02 Aug 2006 01:14 GMT
>> Is it necessary to stay on inhaled steroids while on oral steroids?
>> There is one docotor who says it takes two weeks for Qvar to start
[quoted text clipped - 13 lines]
> rather than try to explain when to stop and restart them. Many patients
> will just stop the inhaled steroid and then never restart it.

Sure, but I'm talking about patients who wouldn't get confused.

> I think it is probably a bit of a tempest in a teapot to argue about it.
> The important thing is that there should not be a gap between the oral
[quoted text clipped - 5 lines]
> start the whole thing and allow the inhaled steroid start from a position
> of already being "kicked in".

So, are you saying that it's okay to hold inhaled steroids until done with
the oral steroids (no gap)?  Both of the doctors who recommended opposing
strategies are equally qualified, IMO.  I understand medicine is not an
exact science.  OTOH, I was just chewed out by the first doctor for holding
off on the Qvar until done with Medrol, though I goofed and forgot to
restart the Qvar immediately.  I missed a couple of days.  But, if I had
done it right, she still did not like it and said I'm going to have to start
from scratch to see if Qvar has any effect (even if I didn't miss any days).
Would you agree with that statement?  Still, I might just stay on the Qvar
next time just so I stay in the habit.
00doc - 03 Aug 2006 01:46 GMT
> So, are you saying that it's okay to hold inhaled steroids until done with
> the oral steroids (no gap)?  Both of the doctors who recommended opposing
> strategies are equally qualified, IMO.  I understand medicine is not an
> exact science.  OTOH, I was just chewed out by the first doctor for
> holding off on the Qvar until done with Medrol,

I think anyone who pretends to know with certainty is full of stuff. Most of
the studies on the topic that I have seen are in emergency departments. In
that population it is better to not just give then the prednisone but to
also start an inhaled steroid. Of course, that selects for people with
certain "access to care issues" and assumes they are not already on an
inhaled steroid.

I don't know how well it applies to patients that are actually making it in
to their regular docs and are already taking an inhlaed steroid. I don't
think there is any literature that directly applies to that situation. In
theory the oral steroid should be doing much more than the inhaled steroid
so there shouldn't be a problem with switching rather than adding.

> though I goofed and forgot to restart the Qvar immediately.  I missed a
> couple of days.

Well, that's the argument for just adding the oral steroids rather than
switching even in people that seem to have a good understanding. This
happens a lot.

> But, if I had done it right, she still did not like it and said I'm going
> to have to start from scratch to see if Qvar has any effect (even if I
> didn't miss any days). Would you agree with that statement?

No. I think the oral steroids will give you a head start on what usually
takes the inhaled steroid alone a while to achieve. Of course it will take
time to assess whether the dose of Qvar alone will hold you but that is the
same situation whether you take it with the inhaled steroids or not.

> Still, I might just stay on the Qvar next time just so I stay in the
> habit.

I don't see how that can hurt and it might help.

Signature

00doc

thingskidssay - 02 Aug 2006 12:13 GMT
When my daughter had an asthma flareup (viral respiratory illness that
as usual sparked an ear infection), our allergy doctor said that we
should stop Flovent and instead nebulize pulmicort twice per day,
albuterol three to four times per day and, in addition, take Orapred
twice per day.  The Orapred is only taken when there is a significant
flareup.  The Pulmicort is started whenever she shows signs of a cold.

My daughter is 3 1/2, was born 7 1/2 weeks premature (very little
oxygen therapy needed from birth), and had RSV-induced bronchiolitis as
a two-year old.  Earlier this year, she had a bout with pneumonia that
prompted the allergy doctor to prescribe Flovent year around.  After
the latest bout, she is also taking Singular.

What a lot of medicines to take!

> Is it necessary to stay on inhaled steroids while on oral steroids?  There
> is one docotor who says it takes two weeks for Qvar to start working, so
[quoted text clipped - 4 lines]
> boosted up and the amount of steroid from Qvar is so minimal in comparison.
> He restarts his hospitalized patients on Qvar after being done with Medrol.
toypup - 02 Aug 2006 15:04 GMT
> When my daughter had an asthma flareup (viral respiratory illness that
> as usual sparked an ear infection), our allergy doctor said that we
[quoted text clipped - 10 lines]
>
> What a lot of medicines to take!

Yeah.  I sometimes think my kids look like little old people from the looks
of the medicine cabinet.  It's even hard to remember what all they're on
when we go to the ped.  I get them confused with each other, so now I'm
writing an asthma diary for each one.
thingskidssay - 04 Aug 2006 11:59 GMT
> > When my daughter had an asthma flareup (viral respiratory illness that
> > as usual sparked an ear infection), our allergy doctor said that we
[quoted text clipped - 15 lines]
> when we go to the ped.  I get them confused with each other, so now I'm
> writing an asthma diary for each one.

The diary is a good idea.  I'm doing roughly the same thing.  A big
problem is that while I think we have a good doctor, we have to trust
them to know the best range of medicines to take.  However, it seems
like every time we go in they have a couple of new medicines (whether
prescribed or over the counter) for us to take.  It makes me very
suspicious when I then see all of the clipboards and pens advertising
medicines!
 
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