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Medical Forum / Diseases and Disorders / Asthma / July 2006

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Change in Inhaler?

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Roger Murray - 12 Jul 2006 08:26 GMT
As I explained in an earlier posting headed Prednisolone. I started
with Asthma about three years ago. At first I was given Asmasal
clickhalors, but the condition gradually got worse and my doctor
switched to a Symbicort Turbohaler. The reason I think was because in
every case positive relief only came after a course of Predisolone
tablets. These were to be taken six 5ml tablets a day over two weeks,
each course amounting to 58 tablets. So far I have had five courses of
these tablets.

Yesterday I was referred to a different doctor at a local specialist
clinic dealing with lung conditions. I explained that the condition was
always completely cleared after a course of Prednisolone, but after
about two weeks of coming off the tablets the symptoms gradually
started to return. First with a cough, then with increasing wheezing
chest until shortage of breath on exertion until I just couldn't
breath, as if somebody had put a bag over my head. I was acutely tired
but felt worse when lying down, and at night felt that I was drowning.
The slightest exertion would bring on the condition.

The young lady doctor was very positive saying that she thought the
asthma was brought on by some permanent underlying problem, rather than
just being allergic to something.  Her thinking was that as the
symptoms always gradually came back after coming off the Prednisolone,
instead of just having attacks by coming into contact with some kind of
irritant, the problem seemed to be caused be some permanent underlying
condition. In fact she wondered if it was asthma in a pure asthma
sense, but something else which she was looking to eradicate.

Her thinking seemed to make sense, although I am not qualified to make
judgement. She sent me off for a chest x-ray which showed as clear and
then took a number of blood tests and asked me to return to see her in
three months

She also took me off the Symbicort Turbohalers to be replaced by a
Flixotide Accuhaler saying that as I seemed to be entirely dependent on
steroid treatment i/e the Prednisolone tablets, which she wanted to get
me off. The Flixotide was more steroid based, but less harmful with
side effects than the Prednisolone tablets.

Apart from this asthma which took me completely by surprise. I am
otherwise healthy, last year riding a motorcycle across the Sahara
desert and the year before across India. So I get plenty of fresh air.

I apologise for this long diatribe of my trials and tribulations but I
am interested in this groups more varied views.

Over here in Cheshire, England I don't think it is as easy to have
open and frank conversation with your doctors as you do in the States.
There is still the left over residue of a medical regime which
considers itself the exclusive custodians of your body and you the mere
mortal are not supposed to know about such things. A kind of mummy
knows best syndrome. Thankfully it is changing fast, but as we have a
National Health system which although is admirable, is massively
overworked, so time with the doctor and specialist is always limited.

Thanks for all your help.

Roger James Murray.
NorthShoreCEO - 12 Jul 2006 13:43 GMT
> As I explained in an earlier posting headed Prednisolone. I
> started
[quoted text clipped - 92 lines]
>
> Roger James Murray.

I've already given you my views in the first post.  Based on what
you've written here, I think I may have been right.  You didn't
seem interested, however, so hopefully you'll find a response you
like when others weigh in.
Roger Murray - 12 Jul 2006 13:53 GMT
My dear North Shore. Yes I was interested, in fact what you said about
a bacteria cause, I suspect is being bourne out. Forgive me if I did
not acknowledge your advice as I should have done, was not intended.
Roger.

> > As I explained in an earlier posting headed Prednisolone. I
> > started
[quoted text clipped - 97 lines]
> seem interested, however, so hopefully you'll find a response you
> like when others weigh in.
angelajoarseneau@gmail.com - 13 Jul 2006 19:50 GMT
Hi there,

I started with antihistamines (Reactine & Benadryl), the pill steroid
(Prednisone), the bronchiodilater (Bricanyl) and the corticosteroid
inhaler (Pulmicort).  After a couple weeks I went off the Prednisone
but had to continue the other treatments.  Later Singulair was added.
It is quite rare that I require Prednisone now.

Controls that give me the bones of a 75 year old are not what I would
call good.  I am sick of breaking bones.  Also I would like to have
kids and from calling the drug companies these drugs are not proven
safe for a fetus.  Steroids suppress growth.

I believe the research at University of Michigan that there is a link
between broad spectrum antibiotics effects on the gut and developing
airway allergies.  So now we have 'em how do we fix 'em.  It's time to
find a cure.  ;)

AJ
Alison Chaiken - 14 Jul 2006 04:09 GMT
Roger writes:
>The young lady doctor was very positive saying that she thought the
>asthma was brought on by some permanent underlying problem, rather
>than just being allergic to something.

Have you considered gastrointestinal reflux disease or a chronic sinus
infection?  Do you have symptoms of either one of those diseases?

Signature

Alison Chaiken            "From:" address above is valid.
(650) 236-2231 [daytime]    http://www.wsrcc.com/alison/
Evolution whispers within us. It does not shout orders. -- L.A. Times
editorial, 05/10/06, via gtb

Richard Friedel - 17 Jul 2006 14:25 GMT
Dear Mr. Murray,

What makes you so darned certain that the purely symptomatic treatment
offered in these backwaters of the medical industry is going to help
you?

Pranayama and especially kapalabhati (forced upper chest breathing
presumably stimulating the sympathetic nervous system) instead to
taking asthma drugs for the same stimulation is frequently recommended
on the Internet.  I'm probably just as allergic to the style in which
articles on it are often written in as you are, but since the medical
industry insists on turning a blind eye to the fact that normal
inhalation (what the asthmatic wants to do)  during normal breathing is
dependent on suction, I'd be skeptical  about its  basic competence.

For an article attempting to explain kapa and other similar techniques
scientifically, see paper by Richard P Brown "On a neurophysiological
model for the effects
of yogic breathing"
http://www.aolresearch.org/pdf/A%20theoretical%20appraisal%20of%20yogic%20breath
.Richard%20Brown.pdf

.  The yogic methods, which produce f. i. orgasm-like stimulation of
the sympathetic nervous system are examined and validated with
functional magnetic resonance imaging (MRI),  see:

"A series of studies reported that Pranayama exercises (including
Bhastrika, Kapalabhati, Nauli, and Agnisara) led to central nervous
system (CNS) excitation. Roldan and Dostalek described three major
excitatory patterns on the brain EEG including a peculiar arc or wicket
rhythm of 12 to 17 Hz with maximal amplitude over the parietocentral
region of the non-dominant hemisphere, a 26 to 33 Hz sinusoidal rhythm,
and a high amplitude paroxysmal activity similar to recordings made
during orgasm in humans and animals."

This seems to mean, putting it loosely, that doing forced breaths (i.
e. those performed with suction during inhalation and taking care to
avoid hyperventilation) and concentrating on the solar plexus (manipura
chakra) to get a voluptuous sensation may overcome an asthmatic spasm
of the bronchi. Regards, Richard Friedel
Roger Murray - 19 Jul 2006 23:19 GMT
Dear Richard. I am not darned certain about the symptomatic treatment
as you refer, or in fact about anything to do with asthma. This is why
I have come to this group for advice.
As I mentioned in my earlier posting, my doctor has now prescribed
Flixodite inhalers. I understand these are steroid based. Are they as
long term harmful as Prednisone?

Roger.
NorthShoreCEO - 20 Jul 2006 01:32 GMT
> Dear Richard. I am not darned certain about the symptomatic
> treatment
[quoted text clipped - 8 lines]
>
> Roger.

Roger, you might want to direct this question to doc.  Richard
feels asthma medication is evil, that all drugs are evil, the
pharmaceutical companies are evil, all doctors are evil and our
entire healthcare system is evil.  Oh, and he lives in Germany.
He'll tell you to strengthen your lungs by putting your finger
between your lips and practicing resistance breathing.  In other
words, I don't think you'll get a decent answer from him.
Richard Friedel - 23 Jul 2006 07:00 GMT
Northshore wrote

"Roger, you might want to direct this question to doc.  Richard
feels asthma medication is evil, that all drugs are evil, the
pharmaceutical companies are evil, all doctors are evil and our
entire healthcare system is evil.  Oh, and he lives in Germany.
He'll tell you to strengthen your lungs by putting your finger
between your lips and practicing resistance breathing.  In other
words, I don't think you'll get a decent answer from him."

Northshore, glad to see we are almost on speaking terms again!

To sum it, I think asthma is a side-effect of our otherwise so
magnificent mainstream medicine which has eradicated so many diseases
like polio, TB, malaria (in Europe) rickets etc. etc. and has shown us
the path to healthy living.

But there are inevitable paradoxes.  One is that the dependency of lung
inflation on negative pressure is ignored.  Snoring is said by docs. to
be due to tissues in the throat "collapsing", while a more probable
explanation would be that the system is producing the necessary
negative pressure.  What is the point of cutting away throat tissues as
an attempted surgical cure?  A primitive human instinct for
self-mutilation?

To take a deep breath usually means inhaling through the nose. This is
nonsense on a strict "scientific" medical view.

By your standards, dear NS, Dr. House (Hugh Laurie) would be an enemy
of mainstream medicine. Maybe your desire for polite harmony, for
maximum consent is anti-scientific.  What did Carl Sagan say about the
need to spin alternative theories? Regards, Richard Friedel
00doc - 23 Jul 2006 16:06 GMT
> Northshore wrote
>
[quoted text clipped - 12 lines]
> like polio, TB, malaria (in Europe) rickets etc. etc. and has shown us
> the path to healthy living.

That's quite possible. It is more plausible that it has to do with a shift
from agricultural to urban living, increasing pollution, home and office
ventilation issues, and the antiseptic paranoia that makes moms fear a
culture positive kitchen counter.

> But there are inevitable paradoxes.  One is that the dependency of lung
> inflation on negative pressure is ignored.  Snoring is said by docs. to
[quoted text clipped - 3 lines]
> an attempted surgical cure?  A primitive human instinct for
> self-mutilation?

That is a fine theory, however, (besides the obvious lack of evidence or a
plausible biologic rationale) it contradicts your opening statement that
modern medicine is causing the increase we are seeing in asthma. Medical
efforts to reduce upper airway resistance such a tonsilectomy couldn't begin
to explain it.

> By your standards, dear NS, Dr. House (Hugh Laurie) would be an enemy
> of mainstream medicine. Maybe your desire for polite harmony, for
> maximum consent is anti-scientific.  What did Carl Sagan say about the
> need to spin alternative theories? Regards, Richard Friedel

I would suggest better sources of information upon which to build your
theories.

Signature

00doc

rchrdcarlisle@NOTyahoo.com - 20 Jul 2006 02:12 GMT
>Dear Richard. I am not darned certain about the symptomatic treatment
>as you refer, or in fact about anything to do with asthma. This is why
>I have come to this group for advice.
>As I mentioned in my earlier posting, my doctor has now prescribed
>Flixodite inhalers. I understand these are steroid based. Are they as
>long term harmful as Prednisone?

Steroid inhalers do not have the same long term harmful effects as
Prednisone since they are inhaled and the absorption into the
bloodstream is minimal and therefore they don't suppress the body's
natural production of cortisol nor have the usual side effects of oral
steroids.  

RC
Roger Murray - 21 Jul 2006 23:39 GMT
Thanks to you all.

Roger.

> >Dear Richard. I am not darned certain about the symptomatic treatment
> >as you refer, or in fact about anything to do with asthma. This is why
[quoted text clipped - 10 lines]
>
> RC
 
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