> On an even better note, there is a product called AllergyBlocker
> that is FDA approved a few weeks ago and this stuff is awesome. No
> side effects, you don't need a prescription, you just rub this gel
> around your nose.
Huh, never heard of that stuff before. Is it just expensive vaseline
or is there an important active ingredient? Does your daughter have
visible grease around her nose or is it all internal?

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Alison Chaiken "From:" address above is valid.
(650) 236-2231 [daytime] http://www.wsrcc.com/alison/
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Bobby - 27 Mar 2006 21:47 GMT
Hi Alison,
I am not sure what the active ingredient is. My wife is the scientist.
A tube of this stuff cost about $10 bucks and lasts about 6 weeks
during allergy season and a few months or more in the winter. We had
our pharmacist order it but you can get in on line at
usefulhealthinfo.com and click on the recomended products (You can also
get it at NasalGuard.com but the other site has a deal where you buy
two and get one free)
No there is absolutly no grease or residue on my nose or my daughters.
Hope this helps.
Bobby
> Anyway, to make a long story short, we found that Xopenex is much
> better than Albuterol in a nebulizer, it last longer and has less side
> effects. Most Doctors don't this but it is now available as an MDI, it
> was approved by the FDA a few months ago!!!
The MDI is new. It has been out as a neb since about 1999. I'm not sure
about the most docs knowing about the MDI formulation part because it
has been heavily advertised.
This medication was just reviewed by The Medical Letter (a non-profit
org that takes no ads - kind of like Consumer Reports for doctors). It
is agreed that the r-isomer found in Xopenex is the active ingredient
of albuterol but there is little to no evidence that it works better or
longer (and no theory to suggest it might).
The idea that the other isomer (the "s" component) is what is causing
the side effects is controversial. The drug company claims about this
are mostly due to test tube experiments on respiratory epithelial
cells. What makes this claim doubtful, besides the lack of clinical
data, is that the r-isomer binds the receptor with 200 times the
affinity as the s-isomer meaning that the equal quantities should have
widely disparate effects.
I'm glad you are doing well with it and I am not trying to discourage
your using it. If someone is having a lot of side effects from
albuterol it might be worth a try. Far better would be to reduce the
use of albuterol through better control of the asthma (but I know that
is not always easy to do). Just keep in mind that the Xopenex MDI costs
about 3-4 times as much as generic albuterol (that difference will
narrow when we go to all HFA forms) and most people will not notice any
difference.

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00doc
Nikki - 23 Mar 2006 19:58 GMT
over the winter (most on here know this I had posted before) my son was in
the mitts of a bad sinus infection that set off his asthma for two straight
months. At one point he sounded bad, I gave him albuterol in his neb. and
took him to the doctors office, once I got there his oxygen was low and he
was raspy they figured it would be worth the try to give him the xopenex, it
did not more or less then the albuterol, he was still raspy, they gave us
the option of changing from one to the other, but since we try hard not to
have to use the albuterol to begin with and did not see a difference we
stayed with albuterol, he is on pulmacurt (spelling sorry) twice a day which
works great and cuts down dramatically the use of albuterol, for the most
part we don't use it unless he is sick from something else and his asthma is
set off because of that. But the doctor did say its just a matter of choice,
xopenex may work better for some people. I would say after years of dealing
with it, if something is working do it, also be aware if you are using
xopenex or albuterol often with a child, or its being used to manage chronic
asthma, the child may need daily "preventive" medicine, for lukes first year
they had him on rescue meds all the time, and now that its being managed...
he is six and plays football, baseball, and does not let having asthma
interfere with his being a kid.
Nik
>> Anyway, to make a long story short, we found that Xopenex is much
>> better than Albuterol in a nebulizer, it last longer and has less side
[quoted text clipped - 27 lines]
> narrow when we go to all HFA forms) and most people will not notice any
> difference.
Bobby - 27 Mar 2006 21:50 GMT
THanks. I should have been more detailed with my post. We got rid of
the carpeting, bought an air filter and use AllergyBlocker on my
daugter and she is off all her drugs. On occasions (Less than once a
month) she needs a nebulizer of Xopenex and my wife uses Xopenex and
she does much better with it than Xopenex.
Bobby - 27 Mar 2006 21:42 GMT
I agree completely doc. I just don't like my daughter on all types of
meds. With the NasalGuard, Air Filters and getting rid of carpet we
have been able to control her Asthma. She now only uses Xopenex once
every several weeks. And yes it was the MDI that I was talking about
being new to the market
Thanks for your info
00doc - 28 Mar 2006 18:27 GMT
Glad to hear it.
It is always better to control the asthma with avoidance of triggers
than meds if it is possible.

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00doc