Medical Forum / Diseases and Disorders / Asthma / November 2005
Climate change linked to rise in malaria, asthma
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Roman Bystrianyk - 02 Nov 2005 11:47 GMT Timothy Gardner, "Climate change linked to rise in malaria, asthma", Reuters UK, November 2, 2005, Link: http://today.reuters.co.uk/news/newsArticle.aspx?type=healthNews&storyID=2005-11 -02T023942Z_01_WRI184112_RTRIDST_0_HEALTH-ENVIRONMENT-CLIMATE-DISEASE-DC.XML&arc hived=False
Climate change may promote the spread of deadly diseases like malaria and asthma in both rich and poor countries by increasing the range of parasitic insects and whipping up dust from storms, a new report says.
As climates warm, malaria is becoming more common in the traditionally cool mountains of Africa, Asia and Latin America where 10 percent of the world's people live, said Dr. Paul Epstein, the lead author of "Climate Change Futures."
"Colonizers escaped (to mountainous areas) to avoid the swamps that bred malaria. Those areas are no longer safe," Epstein told reporters upon presenting the study, noting that malaria cases have quadrupled in the past 10 years and kill 3,000 African babies a day.
Epstein, of the Harvard Medical School, wrote the report in collaboration with reinsurer Swiss Re and the United Nations Development Program.
The report warned that "malaria could suddenly swell in developed nations, especially in those areas now bordering the margins of current transmission."
Scientists believe greenhouse gases, such as carbon dioxide (CO2) released by cars and utilities burning fossil fuels, lead to climate change by trapping the sun's heat in the atmosphere. That can lead to rising seas that may cause flooding and stronger storms.
Rising temperatures increase the range of the mosquitoes and ticks that carry maladies like malaria, West Nile virus and Lyme disease, the study said.
Cases of asthma, which is worsened by particulates in the air, can increase from greater amounts of CO2, the report said. Plants high in pollen and some soil fungi grow better with higher levels of the gas.
WICKED WINDS
In addition, climate change's stronger winds increase the amount of dust in the air from expanding deserts, which compound the effects of air pollutants and smog from the burning of fossil fuels as well as the risks to asthma sufferers, it said.
That could increase the $18 billion that asthma and allergies cost the U.S. health care system each year, according to the report, which lists suggestions large companies could take to reduce their liabilities from greenhouse gas emissions.
Last month, a federal judge dismissed a lawsuit from eight states and New York City against five of the largest U.S. utilities claiming that their emissions were a public nuisance and would cause property harm. The case is on appeal.
The authors of the study hope to bring their findings to corporate boards to reduce climate risks and liabilities.
Companies can lessen risks by joining markets that trade greenhouse gases and by broadening their energy palate from coal and oil to alternatives such as wind and solar power, and possibly, nuclear and hydrogen power, Epstein said.
U.S. President George W. Bush dropped out of Kyoto Protocol on climate change early in his first term.
The agreement created a carbon dioxide market in Europe that allows companies that chose not to cut their greenhouse gases to buy credits from companies that have.
The United Nations will hold climate talks later this month in Montreal in which countries including the United States will discuss how to proceed with the Kyoto Protocol.
Merlin - 03 Nov 2005 00:51 GMT Good Morning Ramon, your post is very interesting and I have some experience working in malarial areas and with persons who have been inflicted with it. One particular circumstance involved a middle-aged woman, she spent only a few weeks in a low risk malarial area and returned to Australia. Shortly after her return she showed odd symptoms and did not relate those symptoms to her trip, they were not traditional malarial symptoms. She was treated with a couple of different antibiotics without any real cure before being referred to a specialist and the Malaria was confirmed. By this stage she had been very ill for a considerable time and various treatments appeared to allow her recovery. She was able to return to her job after some eight months sickness. At this time she began having worsening bronchial problems and was diagnosed with asthma. The odd thing was that she had no previous problem and had a healthy history. She was given steroid medications plus all the other breathing machine medications. Over the next few years her problem worsened and now she is hard case casualty, unable to work and has difficulty with day to day functions with no real quality of life. Any visitors are requested to be clear of any viral problems as her resistance is zero.
As I read the above post it reiterated my original thoughts that more than likely this particular womans tragic downfall would have involved adverse antibiotic effect, coupled with the malaria. The circumstantial elements were obviously present. It is very ironic seeing your post mentioning the two problems together, I do feel that antibiotics and asthma are undoubtedly co-involved in an enormous amount of cases, most especially with young children and have been observing this for more than thirty years.
Another chap I met had been in New Guinea for a short while and had been using "DEET" based insect reppellent skin creams, rather than the normal malarial prophylaxis. He had no asthmatic history but suddenly became quite ill and was treated with antibiotics. He was eventually determined to have "DEET poisoning" and had developed a chemical sensitivity type asthma which he appears to have controlled before he contracted severe Parkinson's. Some people just can't win!! To make it worse his internal organs are "wasting" so he is "buggered". (age 64) Goodness knows whether there is any relationship with the other problems but the antibiotic treatment certainly "stands out", there was no previous asthmatic history.
Cheers, Merlin.
Roman Bystrianyk - 04 Nov 2005 02:11 GMT Merlin,
Thanks for those very interesting stories. In regards to the malaria I would like your opinion on this article I wrote a number of months ago.
Enjoy your day! Roman
http://www.healthsentinel.com/org_news.php?id=025&title=Curcumin+Fights+Malaria& event=org_news_print_list_item
oman Bystrianyk, "Curcumin Fights Malaria", Health Sentinel, February 17, 2005,
According to the World Health Organization (WHO), approximately 300 million people are affected each year by malaria resulting in roughly 1 to 1.5 million deaths worldwide. Previously extremely widespread, malaria exists in 100 countries but is mainly confined to poorer tropical areas of Africa, Asia, and Latin America. More than 90% of malaria cases and the great majority of malaria deaths occur in tropical Africa.
The parasite Plasmodium falciparum is the main cause of severe clinical malaria and death. The parasites are transferred through the bite of infected blood feeding female mosquitoes of the genus Anopheles. In humans, parasites multiply exponentially in the liver and then in infected red blood cells. Mosquitoes ingest parasites with a blood meal, where the parasites undergo another reproductive phase inside the mosquito before being passed on to another human.
The problems of controlling malaria in these countries are aggravated by inadequate health structures and poor socioeconomic conditions. The situation has become even more complex over the last few years with the increase in resistance to the drugs normally used to combat the parasite that causes the disease. Drug-resistance combined with limited availability of antimalarials has contributed to the persistence of this infectious disease.
Curcumin is the bright yellow flavonoid present in the spice turmeric and is used in many Indian dishes. Curcumin has been shown to possess anti-cancer, anti-oxidant, and anti-inflammatory properties. In addition to these properties, curcumin has also been shown to have anti-microbial activity. Curcumin has been found to be safe. It has shown no signs of toxicity in humans in experimental trials taking over 3 months where participants took 8,000 mg of curcumin per day.
Now in the January 2005 issue of Biochemical and Biophysical Research Communications the authors of a study demonstrate the anti-malarial properties of this compound.
The scientists infected 2 groups of mice with Plasmodium berghei and administered curcumin orally for 5 consecutive days, 48 hours after infection in one of the groups. Plasmodium berghei is one of the many species of malaria parasites that infect mammals other than humans. The rodent parasites are not of direct practical concern to man or his domestic animals. The interest of rodent malaria parasites is that they are practical models for the experimental study of mammalian malaria.
The scientists found that the group that was given the curcumin had their parasites reduced by more than 80% and completely protected 29% of infected mice. Those mice that did not receive any curcumin all died within 21 days.
The authors conclude, "curcumin appears to be an ideal antimalarial molecule especially for use in combination with antimalarials such as artemisinin not only to limit the use of the latter but to overcome the problems of high cost, recrudescence [a new outbreak after a period of inactivity], and drug resistance. In view of its abundance, non-toxic nature, and demonstrated therapeutic effects in a variety of human diseases, it will be useful to further investigate the potential of curcumin in developing low-cost antimalarial therapies."
Source: Biochemical and Biophysical Research Communications, January 2005
Merlin - 06 Nov 2005 06:09 GMT G'day Roman, Your paper is very interesting how long does this go back? I am not sure of the name, but I suspect that is the same stuff that some of my friends began using more recently. (In the past five years or so) It required to be taken ideally for two weeks before leaving and a week after their return as far as I can recall, but there was another substance that needed less lead time. The side effect was that they became yellow in their skin pigmentation and as far as I knew that was the only problem. Some really white skinned women became quite brightly coloured, so it was a bit of a joke. Tumeric would explain that, but your article appears to indicate this is a more recent substance again. As a lay-person I found it very enlightening. Many of these mentioned people were long term residents in New Guinea and Bougainville and places like that and it did cause problems needing to use these kinds of things all the time but I don't know what they were using specifically. There is even an odd malaria case from time to time in the really northern tip areas of Australia, but this may be due to people travelling across from NG. Some of these boats have a lot of mossies in the bilges. Many places are now supposed to be clear, Thailand is supposed to be one of these. I am not sure about Vanuatu that is where the woman had been as mentioned earlier. Personally I hated taking the earlier stuff, I think it was chloroquinine but I am not sure. I only took it for short periods because I was only in most places like that for shorter periods. (Like a month or so) Most of the time I avoided the real bad spots and haven't been to Africa or South America.
You would be aware that booze is a no-no with some of these things and in the heat it was always nice to be able to have a nice cold beer if that were possible, so one or the other was removed. Coincidently it was obvious that teetotalers always had health problems of one kind or another. Do you have any idea of alcohol effect with the curcumin? Some of these indian families actually have curry for every meal, so they must have quite a large intake of the tumeric. One place even had "curry icecream" again bright yellow! (probably tumeric) I always wore light coloured or white clothing, it was a most effective mosquito deterrent with a trace of the insecticidal skin cream or aerosol sprayed lightly overall. Meticulous care with nets and burning insecticide coils at night was normal. I also liked to encourage gecko lizards, the translucent white fleshy insect eating type, I actually made a point of catching and relocating them. Oddly enough I have half a dozen of them here presently. (Brisbane) I love watching them gobble insects, especially mosquitoes.
In some places I have seen aircraft tyres literally covered with mosquitoes going for their life trying to get something, so there is definitely something in the dark coloured items although I suppose the tyres stored some heat and had a sofness similar to flesh. I expect an infrared factor would have been involved. You would appreciate the carbon dioxide theory which also appears "on the money". With friends that were unlucky enough to catch the bug it was never suspected as being malaria initially because the symptoms they showed were odd, similar to flu, that was the reason they received strong repeated antibiotics, I believe this symptom is common now. None died, but one is severely affected as mentioned, possibly from the poor health, organ problems and other effects. Dengue was a greater problem for me and was my worst experience, at the time I was alone and really thought it was curtains. Luckily it was the more common variety, not the haemorralgic type. I think the nick-name "Breakbone fever" is an understatement. I have some friends returning that have been on the topside of New Guinea for a couple of years shortly so if there is anything of interest I will repost it. They have had no real problems apart from security which has become a major concern there. It is interesting to see the spice tumeric mentioned, as you are aware it is a common spice used in Indian type curries often using meat which may be "less than perfect" but produces a decent spicy meal which has always been a fair element of my diet in these places, that may explain why some indian families appeared to fare better than others. Cholera and Typhoid was always my main worry as they kept appearing every so often and I was always afraid of antibiotics unless as a last resort. One related interesting finding happened here a couple of years ago, a clever experimenter designed an ultraviolet insect attractant which contained a fan, and as the insects approached the trap, were caught in a moving air current which allowed a centrifugal force effect to impel the insects into a lowered surface tension, water trap, that air continuued as another cycle so the fan power needed, was not all that great. A prior insect count before and after setting this machine, over a large area an acre or so showed a reducton of insects better than eighty percent. The machine was about the size of a four gallon drum. The effect was startling and was noticed here mainly by homeowners in a developing area realising they could venture outdoors without being carried away by mosquitoes. The chap experimenting with the machine was not aware of how efficient it was, or the potential clearing effect. Of course the machine did require frequent emptying of the enormous amount of insect carcasses. You would also be aware of the insect strerilisation techniques being used in some areas for mosquito control. These kinds of ideas together have incredible potential but expense for lesser places would be a problem. Here in Brisbane we have had a very successful mosquito control method by aerial spraying of swamp areas but it needed constant repetition and care with timing because of neap tidal effects and breeding cycles, wind drift and all the rest made it a complicated procedure. In some tropical areas as sunset approaches the mosquito populations are so vast that they resemble a cloud of smoke eneveloping enormous areas and if you are unlucky enough to get caught by it you really go through a lightspeed learning experience. I was silly enough to watch this phenonomenon come toward me from about a kilometer distant and suddenly being inundated by millions of biting mosquitoes, and they bit through your clothes, and you try to hop around slapping your face and every breath is even full of mosquitoes! So by the time you start breathing through a handkerchief and try to cover or move to improve your situation you are being bitten all over your body, I was lucky to be able to make it back to my car and had a can of spray, so having the respite sat incredulous as to how a circumstance like this could happen so simply. It was terrifying. I don't know much about the anopheles but would imagine it would be ultraviolet sensitive. The other one is of course this aedi egypti (spelling) which is of course another matter. Quite obviously with warming comes moisture retention, and increased severity weather conditions, so mosquito populations logically will increase as will disease problem potential. I think the account of the Panama Canal construction is an amazing story where intelligence outside the normal square was the means for achieving success. Your account is very comprehensive with logical conclusions, with my limited knowledge it is very enlightening. Thankyou for the information. Cheers, Merlin.
Roman Bystrianyk - 08 Nov 2005 01:36 GMT Good day Merlin!
Thanks for the interesting reply. The news article was based on a January 2005 research paper. It was done in rats so I am very interested in your stories of people taking turmeric (if that was in fact what they were taking). I am very interested in the results they had if any that you know of. I am not familiar with any effects of turmeric with alcohol. The story of the swarm of mosquitoes was amazing - sounds simply horrifying!
I was also quite interested in that mosquito trapping invention. Sounds fascinating and a potentially wonderful alternative to spraying if it is that effective. Please tell me more via my email rbystrianyk@healthsentinel.com.
Roman
Merlin - 08 Nov 2005 10:38 GMT G'day Roman , reply sent. Cheers, Merlin
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