 |
 | Home | Contact Us | FAQ | Search & Site Map | Link to Us |
 | Sign In | Join | Other 45 Sites in Network |
Medical Forum / Diseases and Disorders / Asthma / October 2005Childhood asthma / increased iron concentrations
Biol Trace Elem Res. 2004 Jan;97(1):31-41. Related Articles, Links Alterations in plasma essential trace elements selenium, manganese, zinc, copper, and iron concentrations and the possible role of these elements on oxidative status in patients with childhood asthma. Kocyigit A, Armutcu F, Gurel A, Ermis B. Department of Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey. The aim of the present study is to evaluate the status of plasma essential trace element selenium (Se), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations and the effect of these elements on oxidative status in patients with childhood asthma. Plasma Se, Mn, Cu, and Zn concentrations were determined by atomic absorption spectrophotometry (AAS) and Fe concentrations, malondialdehyde (MDA), and total antioxidant capacity (TAC) were determined by the colorimetric method. The plasma MDA/TAC ratio was calculated as an index of oxidative status. Plasma albumin levels were measured to determine nutritional status. Plasma Fe concentrations, MDA levels and the MDA/TAC ratio were significantly higher (p<0.001, p<0.001, and p<0.01, respectively) and Se and Mn concentrations and TAC were lower (p<0.01, p<0.05, and p<0.01, respectively) in patients when compared to the healthy subjects. Plasma Zn, Cu, and albumin levels were not found to be significantly different in patients and controls (p>0.05). There were positive relationships between plasma MDA and Fe (r=0.545, p<0.001) and TAC and Se (r= 0.485, p<0.021), and a negative correlation between TAC and MDA values (r= -0.337, p<0.031) in patients with childhood asthma. However, there was no correlation between these trace elements and albumin content in patient groups. These observations suggest that increased Fe and decreased Se concentrations in patients with childhood asthma may be responsible for the oxidant/antioxidant imbalance. PMID: 14742898 [PubMed - indexed for MEDLINE] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking Does iron cause this disorder in children? Or is it found only after the disorder is expressed? If iron causes the disorder why don't all children have it? Why could some children not have excess iron and still get the disorder? Why could some children with excess iron not get the disorder? How does this relate to the iron causes all disease because people eat meat idea? inquiring minds want to know. Does iron cause this disorder in children? Or is it found only after the disorder is expressed? If iron causes the disorder why don't all children have it? Why could some children not have excess iron and still get the disorder? Why could some children with excess iron not get the disorder? How does this relate to the iron causes all disease because people eat meat idea? inquiring minds want to know << Very good questions .... These observations suggest that increased Fe and decreased Se concentrations in patients with childhood asthma may be responsible for the oxidant/antioxidant imbalance. << The researchers seem to think there IS .. an elevated iron .. problem .. Now why would they think that .. ? They found elevated iron in their study .. group .. ? Yep .. I believe that IS .. why .. Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking "Very good questions .... These observations suggest that increased Fe and decreased Se concentrations in patients with childhood asthma may be responsible for the oxidant/antioxidant imbalance." Suggest and demonstrate are two different things. It doesn't answer my questions. Why do some kids get the disorder if having iron or not and is the iron the result of the disorder instead. >>Why do some kids get the disorder if having iron or not << That is up for debate now .. isn't . it .. There are no children .. 'iron deficient' .. unless .. starved .. I think I've heard that .. before .. Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking >>>Why do some kids get the disorder if having iron or not << > > That is up for debate now .. isn't . it .. > > There are no children .. 'iron deficient' .. unless .. starved .. Please explain the cases in which children present in clinic feeling tired, listless and lethargic, but after having been prescribed ferrous sulphate for a few months are bursting with life and energy. Regarding why some get it and others don't in the presence of low or high iron: "That is up for debate now .. isn't . it .." Yup, but it excludes this disorder as being an example of iron causes all disease because people eat meat idea. It is in fact a counter example, only one being required to toss the idea. I have not eaten much red meat or iron in years. I was hoping if anythng this lack of iron might make asthma worse, not vice versa. > Does iron cause this disorder in children? Or is it found only after the > disorder is expressed? If iron causes the disorder why don't all children [quoted text clipped - 3 lines] > How does this relate to the iron causes all disease because people eat > meat idea? inquiring minds want to know. Asthma has always been a sort of self-service store for dabblers in medicine. Regards, Richard Friedel |
Reply to this Message |
 Sign In
 Join
 My Latest Posts My Monitored Threads My Blog My Photo Gallery My Profile My Homepage Start New Thread Enable EMail Alerts Rate this Thread
|
©2008 Advenet LLC Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.