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Medical Forum / Diseases and Disorders / Asthma / July 2005

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Foradil & Serevent

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Jag - 22 Jul 2005 05:33 GMT
Are Foradil and Serevent the same?  I know they are both long acting
bronchodilators.  Is there any advantage to one or the other? Which one is
more effective? Thanks. Jag.
00doc - 24 Jul 2005 15:40 GMT
> Are Foradil and Serevent the same?  I know they are both long acting
> bronchodilators.  Is there any advantage to one or the other? Which
> one is more effective? Thanks. Jag.

The only advantage is that Foradil has a faster onset of action.

Serevent takes about 30 minutes to start working so when it is
prescribed patients need to have a faster acting "rescue" medication
(usually albuterol) and instructions on which to use when.

Foradil has an onset of action within minutes. Its official labelling
calls for the same cautions and concomitant prescription of a short
acting med as Serevent but some people question whether the onset of
action is fast enough to use as a rescue. Albuterol is certainly
faster so if someone did use Foradil in this manner they would need to
be instructed to wait several minutes before taking a second dose and
not expect the relief to come as fast but this is not all that
different than what you get when you use a neb which takes several
minutes to complete.

Where I have really heard this mentioned is in the context of
discussing the combo Foradil and inhaled steroid. If you give this
product and have people use it as a rescue inhaler as well as a
maintenance med you would decrease the number of prescriptions and
automatically titrate the inhaled steroid up when the asthma worsens.
It would kind of become its own self governing action plan.

Of course, some studies should be done before this is widely
recommended and I have not seen anything on this in writing from any
kind of major organization but it is what some specialists are
discussing off the record.

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0doc

pavane - 27 Jul 2005 21:56 GMT
> > Are Foradil and Serevent the same?  I know they are both long acting
> > bronchodilators.  Is there any advantage to one or the other? Which
[quoted text clipped - 27 lines]
> kind of major organization but it is what some specialists are
> discussing off the record.

In general, though, would you find the prescribing of Foradil along with
two puffs of Aerobid both bid to be an innocuous switchover from Advair
250/50 bid or might some cautions be advised?  (VA caused switch,
of course...)

pavane
00doc - 27 Jul 2005 23:20 GMT
> In general, though, would you find the prescribing of Foradil along
> with two puffs of Aerobid both bid to be an innocuous switchover
> from
> Advair 250/50 bid or might some cautions be advised?  (VA caused
> switch,
> of course...)

The Foradil for the Serevent probably is about the same and may have
some advantages.

I'm not sure pff hand how two puffs of Aerobid compares to 250ug of
Flovent (equivalent to two puffs of the 110) but if you flare you
could always just increase the number of Aerobid puffs.

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00doc

pavane - 28 Jul 2005 02:44 GMT
> > In general, though, would you find the prescribing of Foradil along
> > with two puffs of Aerobid both bid to be an innocuous switchover
[quoted text clipped - 9 lines]
> Flovent (equivalent to two puffs of the 110) but if you flare you
> could always just increase the number of Aerobid puffs.

Thanks, I appreciate the information.  The Foradil advantages lie in the
faster action?

pavane
00doc - 28 Jul 2005 03:03 GMT
>>> In general, though, would you find the prescribing of Foradil
>>> along
[quoted text clipped - 14 lines]
> Thanks, I appreciate the information.  The Foradil advantages lie in
> the faster action?

Yes.
 
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