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Medical Forum / Diseases and Disorders / Arthritis / November 2007

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cas - 30 Oct 2007 19:03 GMT
My G P has prescribed 2x paracetmol + 1 Ibruprophen twice daily.I always
thought that you should not take this type of medication together. I have
been on all sorts of medication  over the years and this is the best so
far.can you reassure me that it is O K..thank you ..cas
Harvey R. Stone - 30 Oct 2007 22:39 GMT
> My G P has prescribed 2x paracetmol + 1 Ibruprophen twice daily.I always
> thought that you should not take this type of medication together. I have
> been on all sorts of medication  over the years and this is the best so
> far.can you reassure me that it is O K..thank you ..cas

It will be good for you and your doctor to have a talking relationship.
After you tell him/her about your thoughts, it will be interesting to see
what the doc says.
Harv
J. O'Connor - 31 Oct 2007 00:16 GMT
Well said Harvey, but do you have an opinion on the original question?

John
*************************************

>> My G P has prescribed 2x paracetmol + 1 Ibruprophen twice daily.I always
>> thought that you should not take this type of medication together. I have
[quoted text clipped - 5 lines]
> what the doc says.
> Harv
Harvey R. Stone - 31 Oct 2007 02:27 GMT
> Well said Harvey, but do you have an opinion on the original question?
>
> John

No, I do not.   How about you John?

Harv
J. O'Connor - 31 Oct 2007 02:58 GMT
No, I do not but would love to know the answer.

John
*********************************

>> Well said Harvey, but do you have an opinion on the original question?
>>
[quoted text clipped - 3 lines]
>
> Harv
cas - 31 Oct 2007 08:05 GMT
> No, I do not but would love to know the answer.
>
[quoted text clipped - 13 lines]
>argument amongst you selves which makes me even more worried thanks a lot
>guys'!..cas
Harvey R. Stone - 31 Oct 2007 08:30 GMT
>>I will be seeing my G P tomorrow and will discuss it with her ,I just
>>thought that someone would help on th n/g You seem to be starting an
>>argument amongst you selves which makes me even more worried thanks a lot
>>guys'!..cas

Hi Cas,   Its not an argument.   What your GP has to say is most important
and I do not want to say something that might predice you on what the doc
says.   Please tell us about she has to say.
Harv
california_chief - 31 Oct 2007 18:18 GMT
"cas" wrote"

> My G P has prescribed 2x paracetmol + 1 Ibruprophen twice daily. I always
> thought that you should not take this type of medication together. I have
> been on all sorts of medication over the years and this is the best so
> far. can you reassure me that it is O K..thank you ..cas

It is most often suggested that people ask their pharmacist, instead of a
doctor, about the meds they are taking.

Other sources for drug information include (you'll have to enter the drugs'
names):

http://www.fda.gov

http://drugs-about.com

http://www.rxlist.com
Paul T. Holland - 13 Nov 2007 00:13 GMT
> My G P has prescribed 2x paracetmol

i believe you are referring to the unmonitored, self-administration of
this combination - folk who go and stock up and scarf down quantities
never intended or approved of. there continues to be reported cases of
folk who ingest so much everyday that they go toxic - and indeed, die -
from excessively large amounts - many 1000's of mg a day

your dosage is very low.

which is a brand name for 500 mg ACETAMINOPHEN
"Acetaminophen is a synthetic, nonopiate, centrally acting analgesic
derived from p-aminophenol."
acetaminophen is not associated with a risk for gastrointestinal
bleeding
Most studies do not show any cross-reactivity with the use of
acetaminophen in aspirin-sensitive patients [or with other nsaids].

[Ibruprophen] is 'ibuprofen'
a nonsteroidal anti-inflammatory drug (NSAID)
"The most frequent type of adverse reaction occurring with ibuprofen
tablets is gastrointestinal."
Long-term administration of NSAIDs has resulted in renal papillary
necrosis and other renal injury.

so, the combination would call for monitoring for hypertension, and
liver function, if you are going to be long term.

and in rare cases nsaids can cause serious skin adverse events such as
exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic
epidermal necrolysis (TEN), but it's RARE

be well
paul

+ 1 Ibruprophen twice daily.I always
> thought that you should not take this type of medication together. I have
> been on all sorts of medication  over the years and this is the best so
> far.can you reassure me that it is O K..thank you ..cas
 
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