At the beginning it was a wonderful!  Three weeks after I started it I
was down on the floor plying with legs under the Christmas tree with my
then young son.  I had about three good years on it. I think perhaps
the waning might be from my having to start and stop it so much due to
infections. Then this year I was off of it for almost 5 months due to
severe infections.  Maybe -  but that's just my theory.  I've also
wondered if it's formula has been changed any and that's why it is
having less of an effect. There seemed to be a big drop for me when
they changed to the new once a week formula.  I don't use that one. I
still mix and inject twice a week. But it's like I'm not even taking it
anymore.

It is time to reorder it and I don't want to get three months worth
this time. Last night I threw out three boxes that had lingered on my
refrigerator shelf till they were out of date -- 5/2003!  LOL  They
were from another infection time as well as a shipment that I got that
was from a mailaway pharmacy and not properly cooled.  So when the
replacement shipment came in I just left them there. Man how time
flies!  I couldn't believe when I saw the date!  The box I'm using
right now is for 12/2005.  I wonder if Enbrel is so fragile that its
just not working? Maybe I should order one more month and see what
happens with a fresh box. Anyone have any experience with Enbrel and
expiration dates?  Diane W