> In my case, I got sick the day after once a week. Like a nasty flu(body
> aches and dragging about) at first, and then milder each week. About
> the time the side effects evened out (I was lethargic all the time
> instead of sick once a week) the arthritis got noticably better. When
> it works, it is worth it, despite side effects.
I have ankylosing spondyltis (auto immune arthritis, similiar to RA)
and I was on MTX before I was diagnosed-only for about 2.5 months, and
it didn't do much for me.
I switched RDs and my new one put me back on it (along with azulfidine,
prednisone, Enbrel and some others). After about 3 months this time, I
definitely feel a difference. I am on 8 pills per week now, (20mgs.)
I do get a little nauseous after taking it, so I take it at night,
shortly before going to bed.
LAtely, though, I have been experiencing bouts of dizziness and nausea
3-4 days after taking it. I don't know if this can be attributed to the
MTX or not.
Also, I take the MTX on Weds nights, and by Sunday-Monday, my most
severe symptoms-back pain and heel pain start creeping back. I will
talk to my RD about this on my next appt.
I hope that it works for you, and quickly!!
Charlene
kwendt - 05 Nov 2005 02:19 GMT
> I have ankylosing spondyltis (auto immune arthritis, similiar to RA)
> and I was on MTX before I was diagnosed-only for about 2.5 months, and
[quoted text clipped - 12 lines]
> I hope that it works for you, and quickly!!
> Charlene
Charlene,
I was diagnosed with RA first and started on Humira - did nothing so
switched to MTX and Remicaid - first time it seemed to help but after
that I was still in such pain in my back neck and achilles tendon. This
in addition to the RA symptoms. I also ended up with Crohns and Uveitis
which is not constant but flares frequently. I'm getting one infection
after another . . . Rheumy might try Enbrel but I assumed it was
basically the same as Remicaid. He tested me for the HLA-B27 gene which
can indicate some people are apt to get these autoimmune diseases.
Are you working? I'm 53 and have not been able to work for three years.
Filed for SS disability and after two denials am scheduled before
Christmas before a judge . . .
Karen
Pope Pie (Sy Lehrman) - 05 Nov 2005 16:44 GMT
>> I have ankylosing spondyltis (auto immune arthritis, similiar to RA)
>> and I was on MTX before I was diagnosed-only for about 2.5 months, and
[quoted text clipped - 27 lines]
>
> Karen
I'm working at a Sioux reservation but I'm starting to think about
getting on disability if the situation deoesn't improve in the near
future. I haven't got the energy to eal with these people under present
circumstances.

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Benjamin M. Magno - 07 Nov 2005 05:55 GMT
Just so you know, maybe a leave would be in order. For myself, it took
about two months before the side-effects were tolerable, and even then
not much. They do get progressively more manageable as you get used to
it.
Pope Pie (Sy Lehrman) - 07 Nov 2005 07:16 GMT
> Just so you know, maybe a leave would be in order. For myself, it took
> about two months before the side-effects were tolerable, and even then
> not much. They do get progressively more manageable as you get used to
> it.
Thanks for the tip. At the moment i'm also taking prednizone and
therefore feeling much better. It is supposed to be a bridge until the
MTX starts to take effect. We shall see...

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Harvey R. Stone - 07 Nov 2005 12:55 GMT
>> Just so you know, maybe a leave would be in order. For myself, it took
>> about two months before the side-effects were tolerable, and even then
[quoted text clipped - 4 lines]
> therefore feeling much better. It is supposed to be a bridge until the
> MTX starts to take effect. We shall see...
Grapeseed extract and Biotin for thinning hair side effect. Methx did
nothing for me until I got up to 15mg/week and then it was 17.5mg/week for
7-8 years.
Most of those years with prednisone and sulfasalizine.
Good luck,,,\
Harv