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Medical Forum / Diseases and Disorders / Arthritis / October 2005

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Prednisone..when the heck does it let you sleep

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jo - 03 Oct 2005 20:44 GMT
Well am doing great on this med..pain is at an all time low, am also
able to unclench my left hand for the first time in 2 years..
House is clean and moral is high..but I think I need more than 3 hrs a
night of sleep. Wow my family keeps teasing me they'r going to take my
pills away from me....thank to you all who strongly supported taking
this med
I turned 50 yesterday and I feel better than I did at 45..
Any suggestion on how to achieve that great, all nesty, feeling of
needing to go to bed..
johnie - 03 Oct 2005 23:15 GMT
well jo, the old demon has got you now.>g< Most likely you will be able
to get rid of the pred once you find a DMARD therapy that works amd
with a little luck keep some of those energy levels. Unfortunately, i
have not responded well to any DMARDS so i have been stuck with the
pred for about 15 years this round. Long term pred use can be very
destructive (so it goes).

As for sleep, you will in general need less for awhile. Enjoy it. It
won't last. I think you mentioned that you were taking an afternoon
dose. If so stop that and take all of your pred between 5 and 7am. That
coincides with your normal adrenal release and will not effect your
sleep nearly as much.

Good luck and enjoy the reprieve from 'arthur'. I am a bit envious. I
remember the feeling from that first round of pred all too well... It
was an extremely spiritual experience.>bg<

johnie

> Well am doing great on this med..pain is at an all time low, am also
> able to unclench my left hand for the first time in 2 years..
[quoted text clipped - 5 lines]
> Any suggestion on how to achieve that great, all nesty, feeling of
> needing to go to bed..
Harvey R. Stone - 04 Oct 2005 03:43 GMT
> well jo, the old demon has got you now.>g< Most likely you will be able
> to get rid of the pred once you find a DMARD therapy that works amd
[quoted text clipped - 14 lines]
>
> johnie

Hi Jo,,,,  johnie has told it just like it is.   Please pay attention about
taking a heavy hitter DMARD if you have inflam.arth....  Like Kitty, and
johnie there are some people that their body just will not put up with DMARD
therapy and must make it on steroids.
    You have read the worries we have from taking too much prednisone for
too long.   Just like johnie said,,, I had to move my afternoon dose back to
the early and late morning to be able to sleep well at night.  I had to
smile at your joy in being able to do some things again.
So many of us have been there.   I have a full months supply just setting
there because I do not take it anymore but I have it if I need it.  Please
do not over do.... your muscles and tendons will pay you back.
   My right knee was like your hand.  I just would not bend it enough to
make the curb or step and down I would go.  Sooo embarrassing.   Good luck
with it all and keep the pressure on for medicine that will let you get off
prednisone.
Harv
Squirrely - 04 Oct 2005 01:14 GMT
Jo,

I sure hope you keep feeling better all the time. Happy Belated Birthday to
you. You take care and know that I am thinking of you. I hope you get some
good sleep soon.

The only thing that makes me sleep half way decent is I take an ativan
before bed. That knocks me out in about an hour after taking it and then
keeps me asleep for about 5-6 hrs.

Signature

Love and hugs to all
Good thoughts coming your way too.

Squirrely Jo

Jo Firey - 04 Oct 2005 01:22 GMT
> Well am doing great on this med..pain is at an all time low, am also
> able to unclench my left hand for the first time in 2 years..
[quoted text clipped - 5 lines]
> Any suggestion on how to achieve that great, all nesty, feeling of
> needing to go to bed..

Welcome to my world.  (And your family probably isn't teasing)

I don't recall how much pred you are taking or how long you might have to
take it.  I know if I take a high dose burst - usually for my asthma, I will
sleep plenty when I get back off it.  Like a zombie.

What I truly hate is to be brimming over with pred energy and too ill at the
same time to do much of anything with the energy.  Except to plan recipes in
my head for all the things I'm going to cook as soon as I'm well enough to
stand up.

If you are on a long term fairly low dose, sleep will eventually catch up
with you as your body adjusts.

Jo
Alison DeLorme - 04 Oct 2005 02:26 GMT
glad to seethe pred is working for you. I know many people have the best
luck with taking pred in the early morning, basically letting it wear off
throughout the day so that at bedtime they can sleep. I was the opposite. I
found the best time was just before bedtime (11pm or so). I would fall
asleep before the hyper-state would kick in and I never had any problems
staying asleep - as long as something (like my 3 children) didn't wake me in
the middle of the night. If they did, then I often had a hard time going
back to sleep.  Another benefit to the pred at night was that it helped keep
the morning stiffness at bay. My pred timeclock ran about 20 hrs - meaning I
was 4hours short for 24hr relief. But taking it at night, the slow down
would be in the late evening time, when I would be resting anyway. And since
I am always more limber and hurt less at night then the morning, it worked
well for me.... it's worth a try if the early morning dose doesn't work for
you...

alison
spodosaurus - 04 Oct 2005 03:50 GMT
> Well am doing great on this med..pain is at an all time low, am also
> able to unclench my left hand for the first time in 2 years..
[quoted text clipped - 5 lines]
> Any suggestion on how to achieve that great, all nesty, feeling of
> needing to go to bed..

Stillnox  :-)

I'm only on 15mg a day and I haven't slept more than 3 continuous hours
in 7 to 8 weeks.

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spammage trappage: remove the underscores to reply

I'm going to die rather sooner than I'd like. I tried to protect my
neighbours from crime, and became the victim of it. Complications in
hospital following this resulted in a serious illness. I now need a bone
marrow transplant. Many people around the world are waiting for a marrow
transplant, too. Please volunteer to be a marrow donor:
http://www.abmdr.org.au/
http://www.marrow.org/

jo - 04 Oct 2005 11:59 GMT
am now on 20mg a day for the next 4 days...I don't have a Rheum but my
gp prescribed the pred..so I'll try to contact her today. I had a
doosey of a panic attack last night but am sure its due to lack of
sleep.   So this am I took 10mg at 6am, am thinking of taking the other
10mg at 8am, but I wonder if its too soon after the first dose. Harvey,
I take 1/2 tab of clonazepam (0.5mg) but it sure didn't work last
night....so this am I feel flushed and strung tigher than William
Tell's bow...
Hope that my gp finds a Rheum so I can look into this DMARD therapy I
have read about here over the last couple months.
Stillnox, what do you do with the other 21 hours in your day.:-)))))))
Hugs to you all and wish for a gimpless day..I'm going to go see if
there's dustball under the fridge :-))))))))))
Harvey R. Stone - 04 Oct 2005 14:38 GMT
> am now on 20mg a day for the next 4 days...I don't have a Rheum but my
> gp prescribed the pred..so I'll try to contact her today. I had a
[quoted text clipped - 9 lines]
> Hugs to you all and wish for a gimpless day..I'm going to go see if
> there's dustball under the fridge :-))))))))))

Oooh, I hate that kind of feeling.   The last time I felt that way, I had
jury duty the next day and did not sleep well the night before.   My right
knee  was big as a grapefruit and the pad behind my toes on my left foot
felt like I forgot an icepick in it.   That was a long day and so was the
next one.   I had taken extra prednisone to try to get through all those
tunnels and stairways a person has to use in downtown Houston.   I was wired
and it is a good thing they took the DAs offer and went to jail.   I was
going to bring my own rope.   LOLOL

    I think you need to get with your GP and let the doctor know how you
feel.   That may be too much pred for you.   Please push for an appointment
with an RD.

Harv
Mary Z - 04 Oct 2005 14:47 GMT
>  So this am I took 10mg at 6am, am thinking of taking the other
>10mg at 8am, but I wonder if its too soon after the first dose.

If you do a query on this Newsgroup I will bet you find most people
take the entire dose in the AM.   taking prednisone in the evening
will definitely interfer with your sleep.   You need to push your GP
into seeing a Rheumatologist, you have had this for months and they
don't have you on a DMARD yet?   Doesn't sound like proper treatment
to me.

Visit my website:
http://www.mzuschlag.com
Charrlygrl1 - 04 Oct 2005 21:18 GMT
Hi Jo!
I'm soo glad that you're feeling better. However, prednisone is not
something that you want to be on for very long, if there is an
alternative that works for you.
DMARDS, NSAIDS or biologics...or in my case some of each!
Prednisone certainly makes you feel better, but it does nothing to stop
the progression of the arthritis (or whatever the problem may be).
Again, I am glad that you're feeling better!
Charlene
joQC - 04 Oct 2005 21:40 GMT
My understanding is that I will do 15 mg for 5 days beginning Friday,
then 10 mg for another 5 days, then 5mg beginning on the 17 of october
but I see no stop date on the calendar my phamarcy gave me.
So if I did 5 days on 5mg and stopped on Oct 21 , I will have been on
Pred for 25 days and taken a total of 325 mg of Pred......as i said in
earlier post I went to see the GP but she said to return sometime at
the end of October when I was down to 5mg.
Tks to all of ((((you)))) for taking the time to respond and give of
your own experience, its extremely helpfull in removing fear of
meds.... In earlier post someone noted " Fear the disease not the Meds
" I thought that's a good way to think outside of the box
again thks :-)))))
spodosaurus - 05 Oct 2005 09:31 GMT
> Hi Jo!
> I'm soo glad that you're feeling better. However, prednisone is not
[quoted text clipped - 3 lines]
> Prednisone certainly makes you feel better, but it does nothing to stop
> the progression of the arthritis

Hmmm...doesn't the anti-inflamatory effect of prednisone reduce the
progression of inflamatory damage to the joints? Pred also reduces
lymphocyte counts and suppresses their function, and in RA it's the
T-cells that are actively attacking the joints.

> (or whatever the problem may be).
> Again, I am glad that you're feeling better!
> Charlene

Signature

spammage trappage: remove the underscores to reply

I'm going to die rather sooner than I'd like. I tried to protect my
neighbours from crime, and became the victim of it. Complications in
hospital following this resulted in a serious illness. I now need a bone
marrow transplant. Many people around the world are waiting for a marrow
transplant, too. Please volunteer to be a marrow donor:
http://www.abmdr.org.au/
http://www.marrow.org/

Jo Firey - 04 Oct 2005 22:20 GMT
>>  So this am I took 10mg at 6am, am thinking of taking the other
>>10mg at 8am, but I wonder if its too soon after the first dose.
[quoted text clipped - 5 lines]
> don't have you on a DMARD yet?   Doesn't sound like proper treatment
> to me.

I've always either taken it  all at once first thing in the morning, or else
very late at night.  Most of my doctors have agreed with this.  Yes it only
gives you 20 rather than 24 hours coverage, but you gotta sleep sometime.

Jo
Charrlygrl1 - 05 Oct 2005 19:01 GMT
Spod,
Perhaps I should've phrased that differently, you are right. Prednisone
does have immuno-regulatory properties as well as being a strong anti
inflammatory. However, since long term use at high dosages is so
dangerous, maybe I should've said that unless there is no other choice,
prednisone is not the primary treatment of choice for erosive
arthritis, (though for those who don't respond to DMARDS, NSAIDS, or
cannot take them for whatever reason, sometimes there is no choice).
Following is a quote from John Hopkins:

Corticosteroids have both anti-inflammatory and immunoregulatory
activity. They can be given systemically or can be injected
intra-articularly. Corticosteroids are useful in early disease as
temporary adjunctive therapy while waiting for DMARDs to exert their
antiinflammatory effects. Corticosteroids are also useful as chronic
adjunctive therapy in patients with severe disease that is not well
controlled on NSAIDs and DMARDs. The usual dose of predinisone is 5 to
10mg daily. Although prednisone can be started at higher doses (15 to
20mg daily), attempts should be made to taper the dose over a few weeks
to less than 10mg daily. Once started, corticosteroid therapy is very
difficult to discontinue and even at low doses. Tapering of prednisone
should be done slowly over a few weeks and symptoms may reoccur with
small changes in the prednisone dose.

Thanks for pointing out my error,
Char
Squirrely - 14 Oct 2005 15:17 GMT
Jo,

Happy Belated Birthday.

I use Ativan at night to sleep and also for the anxiety that I suffer
because of the thyroid stuff.
It helps me sleep.

Signature

Love and hugs to all
Good thoughts coming your way too.

Squirrely Jo

> Well am doing great on this med..pain is at an all time low, am also
> able to unclench my left hand for the first time in 2 years..
[quoted text clipped - 5 lines]
> Any suggestion on how to achieve that great, all nesty, feeling of
> needing to go to bed..
 
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