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Medical Forum / Diseases and Disorders / Arthritis / July 2005methotrexate and mood problems
I would be curious to find out how many who have been on methotrexate and suffered mood swings and depression. I am really thinking that the gradual increase of the mtx each time is causing more and more depression and mood changes. They don't last all the time but I also am experiencing anxiety which all of this in not the norm for me. Thanks Becky >I would be curious to find out how many who have been on methotrexate and >suffered mood swings and depression. I am really thinking that the gradual [quoted text clipped - 3 lines] > Thanks > Becky I had problems with depression and anxiety long before I ever heard of MTX. And being in bad enough shape to need it doesn't help with either problem. Jo I am 28 and have been on Methatrexate for 4 years and have not had those side affects, however everyones body is different and medicane reacts different. I hope it gets better for you. Have you taked to your doctor about your side affects? > I would be curious to find out how many who have been on methotrexate and > suffered mood swings and depression. I am really thinking that the gradual [quoted text clipped - 3 lines] > Thanks > Becky I am always tearful the day after my MTX. Look at me crossed eyed and I start bawling. It only lasts for day though, thank goodness!! ~KJ the cry baby! >> I would be curious to find out how many who have been on methotrexate and >> suffered mood swings and depression. I am really thinking that the [quoted text clipped - 10 lines] > > ~KJ the cry baby! I get irritable, which I find is reduced if I sleep and drink a lot of water. I also take an extra 2 mg of folic acid the day I take my shot. Walt >I would be curious to find out how many who have been on methotrexate and >suffered mood swings and depression. I am really thinking that the gradual [quoted text clipped - 3 lines] >Thanks >Becky I don't believe that I had mood swings as a result of mtx, however, during the first few years I had profound fatigue following my injections. As a result, my Rd switched me from folc acid (5 mg per day) to leucovorin which is folinic acid. I know that even the folic acid was at a doseage higher than the norm. What dose are you on? Rose @}>->-- Being educated means that rather than fearing the unknown, one seeks to understand it. RB Please remove "Ima" to reply. I am also on MTX since April. My doseage is still quite low but needs adjusted as I go and according to my blood work. I found I feel like crap the day after the injections but that is lessening now. I do get headaches lately but now they think it is not due to that drug but my cervical spine. Here we go again, injections to that. Then the mtx also gives me the "goes" which I can use, since my bowels have gotten so sluggish TNT won't move them sometimes :) But moods? Naw, I still am the jolly, funloving, wierd person I always have been...hehe good luck janers Thanks for all the replies, I can not take folic acid in any pill form but do it the foods with it. I am just about ready to give up, I called the RD doc, he said well back off it for awhile or take a lower dose and see what happens. He really didn't know he said. So I am back to me deciding what to do like usual. He did give me a scrip for enbrel and I will be discussing that with him in 2 weeks. Thanks Becky >I am also on MTX since April. My doseage is still quite low but needs > adjusted as I go and according to my blood work. [quoted text clipped - 12 lines] > > janers > I would be curious to find out how many who have been on methotrexate and > suffered mood swings and depression. I am really thinking that the gradual [quoted text clipped - 3 lines] > Thanks > Becky Are you on anything else that might contribute to these changes, such as prednisone?  Signaturespammage trappage: replace fishies_ with yahoo I'm going to die rather sooner than I'd like. I tried to protect my neighbours from crime, and became the victim of it. Complications in hospital following this resulted in a serious illness. I now need a bone marrow transplant. Many people around the world are waiting for a marrow transplant, too. Please volunteer to be a marrow donor: http://www.abmdr.org.au/ http://www.marrow.org/ No, the only thing I have added since feeling like this is MTX, didn't effect me like this until I reached the 17.5 mg really badly, started probably around the 15mg but needed to increase because it wasn't strong enough. I have also been experiencing a lot of pain in my right hip area, and very tight muscles. Who knows, someday I am not sure why I even bother to get out of bed. Thanks for asking though Becky >> I would be curious to find out how many who have been on methotrexate and >> suffered mood swings and depression. I am really thinking that the [quoted text clipped - 6 lines] > Are you on anything else that might contribute to these changes, such as > prednisone? >I would be curious to find out how many who have been on methotrexate and >suffered mood swings and depression. I am really thinking that the gradual [quoted text clipped - 3 lines] > Thanks > Becky Hi Becky, I don't post much at all, but saw your post and had to reply. I haven't taken my MTX is some time (hmm, several months I'd say. Humira alone is holding me over just find). For many months I was taking 20mg of MTX by injection, and had the usual fatigue and nausea the next day, nothing out of the ordinary. Then a couple doses I started feeling very woosey afterwards. Very anxious, heart was racing, at one point at resting it was clocked at over 100 bpm (taken with my boyfriend's heart rate monitor he uses while bike riding). The last dose I took of MTX was the worse. Within a couple of hours, paranoia, to the point of not being able to sleep, thinking people were scaling the building to come into my 4th floor apartment. I mentioned it to my RD, who didn't think it was the MTX, and told me to continue taking it, see if I experience it again. Ah, no, I don't think so. Definately it is something you should mention to your doctor. As others have said, everyone reacts differently to the medications we take. Nicole G Hi Becky, The day after I take MTX, I feel tired and have the blahs. I can see how it could cause mood problems from some folks. Just be glad that we are not taking the high dose that cancer patients take! Ray |
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