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Medical Forum / Diseases and Disorders / Arthritis / June 2005Enbrel once a week
In the UK we are about to get the choice of once a week 50 mg Enbrel (Remember - Engerland swings like a pedulum do ?) I just wondered if any of you folks in the US who have been taking it for some time have noticed any differences between 2 x 25 mg and 1 x 50 mg per week ? - Like maybe towards the end of the week you get more painful - for instance Peter Hi Peter, I've been doing the 50mg for a while now and I do not feel worse towards the end of the week. However, for me, the injection itself burns a bit going in. I don't know if it's the concentration of the medicine or what. The burn only lasts for as long as I am injecting, then goes away. Not a big deal given the benefits. Enbrel's been great. Peace... Melvin > In the UK we are about to get the choice of once a week 50 mg Enbrel > (Remember - Engerland swings like a pedulum do ?) [quoted text clipped - 5 lines] > > Peter > Hi Peter, > [quoted text clipped - 8 lines] > Peace... > Melvin Hi,,, I actually liked the twice a week better. The once a week does burn a little but not enough for me not to take it. Harv > In the UK we are about to get the choice of once a week 50 mg Enbrel > (Remember - Engerland swings like a pedulum do ?) [quoted text clipped - 5 lines] > > Peter My wife switched to once a week (50 mg) and aside from the minor burning notices no difference in the effect. Embrel has been quite helpful in her opinion for her quite severe RA. On balance she refers once per week. I have been on the 50mg shot for a couple months and it's ok. It burns quite a bit more than the 25mg ones. Previous to the new shots, I had taken 2 25mg once a week and liked that much better. No burning - same great effect. I found the once a week dosing worked much better for me. I do feel a bit of a fade on the last day or so. But with doing it twice a week, I found that relief only lasted a couple days, with a fade following so I'd be in greater pain a day or two before each shot (meaning twice in a week). The only thing I didn't like about those shots is that I always developed big welts that would last a few days. very itchy. And when I was taking the shots 2x/wk it basically menat I always had a welt. With the new single dose shot, I don't get the welts anymore. They must have changed the makeup of it a bit... alison I've only been on Enbrel for a few months, with a one month break in there due to other illnesses. I was never on the 2X/week shots. The one/week does burn some going in, but when it gets to be too much, you just pause for a couple of seconds until it eases off. Once I left it out longer than usual to warm up because I accidently leaned on the digital timer and reset it. not sure how long it was out, maybe 45 minutes, maybe an hour. It didn't burn at all that time. I don't want to risk letting it get too warm on a regular basis though. I have been letting it stay out closer to 30 minutes now rather than 15 and it does burn a bit less. I do wonder how I would have done on the twice/week shots. I have some fade and do feel it kick in, but having used it only 4 of the last 5 months, I'm still hoping that will disappear over time. It definitely took a solid 2 months for the Enbrel to begin helping my costochondritis. My fatigue improved from the very beginning though.  SignatureNann remove the Gator cheer to email me Simply the thing I am shall make me live --- William Shakespeare Hi, I am wondering; until some time ago I was on 7,5 mg pred plus twice a week 25mg Enbrel, lowered the dose to 5 and that managble just. I am now on 2,5 mg pred and twice a week, no,I should say every 4th day on Enbrel as my rd wants me to come of Pred because of it's side effects and my age. The 2,5 mg is just not enough, I have tried for almost 3 months now and am scared to think what I will feel like on just being on Enbrel. I was thinking of either shoot Enbrel every 3rd and every 4th day since my rd told me many people who are on 50mg once a week need to take the shots more frequently in the end anyway and there were more side-effects. He reckoned there was no use in shotting 50mg once a week. BUT reading about your taking a shot once a week, I would like to give it a try, if it were just to see if I can avoid the twice a week fade. What worries me though is the burning. I never used to be afraid of needles, but since I experienced a really rough dr who apparently thought of the needle as a darts-arrow, I would rather go for 2 needles at the same time once a week than a bigger needle that burns. What do you think, anyone done this before? Nikki > I've only been on Enbrel for a few months, with a one month break in there > due to other illnesses. I was never on the 2X/week shots. The one/week does [quoted text clipped - 11 lines] > months for the Enbrel to begin helping my costochondritis. My fatigue > improved from the very beginning though.
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