Medical Forum / Diseases and Disorders / Arthritis / May 2005
MTX Availability
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roby - 25 May 2005 17:52 GMT I switched from methotrexate tablets to injectable by mouth about three years ago: three months worth of injectable is $8.75 vs $30.00 for tabs from Medco. Late last year, the (lpp) injectable became unavailable. Today, I learned that Medco still can't get injectable ... and I was amazed to hear that they don't have generic MTX tablets either! My latest refill will be Trexall ($60).
Sooooo, my MTX cost jumped from $35 to $240.
They had no words about why the generic was not available, or whether this was a temporary situation.
Anybody know more?
Roby
Harvey R. Stone - 25 May 2005 18:37 GMT My latest refill will be Trexall ($60).
> Sooooo, my MTX cost jumped from $35 to $240. > They had no words about why the generic was not available, or whether > this was a temporary situation. > Anybody know more? > > Roby Hi Roby,,,, I wish I did know more. I have my questions about this shortage. Someone,,,Anyone should look into THE LOSS OF A CHEEP DMARD which can only be subbbbed with a way more expensive DMARD..... These shortages smell fishy to me. IF and I say if today's cancer treatment is being done with newer drugs and Methx is no longer needed,,, I might understand it As everyone here knows that I believe in the free market BUTTT this is starting to smell. Harv
Nanny - 29 May 2005 20:22 GMT I haven't been taking oral MTX for a long time, but with insurance, I am paying $10 for a 30-day supply. Shhh...don't tell anyone - I want it to continue. Nanny
> My latest refill will be Trexall ($60). >> Sooooo, my MTX cost jumped from $35 to $240. [quoted text clipped - 13 lines] > is starting to smell. > Harv Ron Stewart - 25 May 2005 19:14 GMT What does "injectable by mouth" mean? I have never had a problem buying generic MTX injectable at the local drugstore. I get a 6 month supply for $22 and a 2 year supply(100) of syringes for $20. Our insurance company uses Medco but the preapproval process is such a hassle I just pay out of pocket since it is so cheap.
 Signature Ron Stewart Santa Rosa, Calif.
>I switched from methotrexate tablets to injectable by mouth about three >years ago: three months worth of injectable is $8.75 vs $30.00 for tabs [quoted text clipped - 11 lines] > > Roby Harvey R. Stone - 25 May 2005 21:38 GMT > What does "injectable by mouth" mean? What they meant to say is pill taken by mouth. You are very lucky to not have had your supply interrupted.
Harv
roby - 25 May 2005 23:02 GMT > What does "injectable by mouth" mean? > I have never had a problem buying generic MTX injectable at the local > drugstore. I get a 6 month supply for $22 and a 2 year supply(100) of > syringes for $20. Our insurance company uses Medco but the preapproval > process is such a hassle I just pay out of pocket since it is so cheap. I draw the dose into a syringe and "inject" it into a glass of orange juice. Well, those were the good old days.
You are fortunate to have access to generic MTX in either form.
Roby
Lyn - 26 May 2005 02:30 GMT I just ordered a refill on mtx from Medco on Sunday, (pills), just got the shipment verification notice, will be here in 2 - 5 business days. 3mth supply $20.
Lyn
> I switched from methotrexate tablets to injectable by mouth about > three years ago: three months worth of injectable is $8.75 vs $30.00 [quoted text clipped - 11 lines] > > Roby Nanny - 29 May 2005 20:23 GMT >I just ordered a refill on mtx from Medco on Sunday, (pills), just got the >shipment verification notice, will be here in 2 - 5 business days. 3mth [quoted text clipped - 17 lines] >> >> Roby Nann Bell - 26 May 2005 05:00 GMT > I switched from methotrexate tablets to injectable by mouth about three > years ago: three months worth of injectable is $8.75 vs $30.00 for tabs [quoted text clipped - 11 lines] > > Roby they *should* have the generic pills, but your tale goes along with other horror stories I've heard about Medco. Depending on what your out-of-pocket costs are, it might be worth it to you to get the pills from a local pharmacy rather than through the mail. You'd be able to get the generic from them. Or sic your insurance company on Medco if your policy is cornering you into using them. The insurers can't be happy with covering a brand name rather tahn a generic.
Anyway, I got mine filled, locally, just a couple of days ago without any trouble. And this at a small-town pharmacy that keeps limited supplies on hand (I always make sure I give them plenty of notice on refills!) Oh, I should say that was generic tablets - I handle the pills well and we never switched me to the injectable.
 Signature Nann remove the Gator cheer to email me Simply the thing I am shall make me live --- William Shakespeare
janers - 26 May 2005 14:22 GMT The MTX pills are available.
It is the injections that are hard to get. I also use Merck Medco and they have not been able to get the injections, nor has any pharmacy near me or for that matter FAR from me.'
The company that manufactures MTX, and I called them, will be back in business by mid JUNE they said. Plus Bedford labs will also have it.
Please hang in there for the injections. WE hope they keep their word and are on their way. But I agree with others, this is damn stupid to not have the drug in the first place.
janers
Walt Hanks - 26 May 2005 15:45 GMT And again, my pharmacy has an ample supply. I really think these "shortages" are being made worse, in part, by lazy/uninformed/whatever, distributors who just don't take the time.
Walt
> The MTX pills are available. > [quoted text clipped - 12 lines] > > janers Karen - 26 May 2005 20:35 GMT > The MTX pills are available. > [quoted text clipped - 11 lines] > > janers My Dr. told me 2 weeks ago that the companies are changing MTX and putting a preservative in it, and you'll only be able to get your injections at the Dr.'s office. I did find two bottles that will keep me going for a while. (only taking .3 a week)
I wonder if the mfg getting back in business by mid June, it will be the "new kind"?
janers - 27 May 2005 01:28 GMT Was told just the injection type of MTX.
I also use the preservative type and this is the one that apparently out. I got vials 4 of them right now from a older smaller pharmacy. It is a vial with 50mg in it. If you use .3 cc then that is what I use and that equals 7 1/2 mgs. Enough for about 7 shots or month a half. You do not have to get that at a doc office. If you know how to inject yourself and are given instructions on dosage there is no problem. the vials that have no preservative are much more expensive too, that is what I hear.
And my doc and myself contacted 12 local pharmacies and each pharm guy told the same story. Not available. Plus is you go to available drugs on line or ones that are being back ordered? There is the MTX right there saying it is out of stock ...so someone has them somewhere in a back storage room Note on all vials has the expiration date and last longer in storage than the NO preservative. Plus once you break a vial of No preservative, you are suppose to throw away the rest if you do not use it right away. Does anyone do that??? Fess up now LOL
keep the faith, the MTX hopefully will be there soon
janers
Walt Hanks - 27 May 2005 11:26 GMT > Plus once you break a vial of No preservative, you are suppose to throw > away the rest if you do not use it right away. Does anyone do that??? [quoted text clipped - 3 lines] > > janers Actually, Bedford is recommending that the preservative free MTX be stored in syringes to maximize storage life and get multiple doses from a vial. I take 20 mg/week; that's 0.8 cc. So when I open a vial, I draw two full syringes and a half a dose. I recap one of the full syringes and the half dose and put them in a bag, then take the other dose. Two weeks later I inject the half dose into a new vial, then draw three complete doses. This way I get 5 doses from two vials.
Again, this is per manufacturer's guidelines.
As to the preservative vs. non-preservative, I believe the story is that the two manufacturers that were shut down by the FDA (which is what caused the shortage) have only been certified to produce MTX with preservative. Bedford will continue to produce the preservative-free variant, which those of us who are sensitive to the preservative will need.
Also, Bedford announces the release of each batch in advance and pharmacies are instructed to call and order what they need on the release day - not before. Following these instructions, my pharmacist has always been able to get what she asks for. But other pharmacists in the area, who don't follow instructions, don't get any.
Finally, if someone is taking injectable MTX orally, they might consider switching to the IV solution instead. It can also be taken orally and has not been in as short a supply.
Walt
janers - 27 May 2005 17:19 GMT Hey there, do you known what the preservative does to some people? side effects?
I have not heard nor read much about that, so if you have links or the who's, why's or wherefore's then fill me in here. Love the info.
thanks bunch for your informative information
janers
Walt Hanks - 30 May 2005 01:54 GMT Hi there. Just got back from my Sister's wedding in San Diego. Sorry I didn't reply sooner.
For me, the problem is a strong injection site reaction (redness, pain, etc.) Others can have an allergic reaction.
Hope that helps!
Walt
> Hey there, > do you known what the preservative does to some people? side effects? [quoted text clipped - 5 lines] > > janers RoseB - 30 May 2005 02:05 GMT >Hi there. Just got back from my Sister's wedding in San Diego. Sorry I >didn't reply sooner. [quoted text clipped - 5 lines] > >Walt hmm. Interesting. I have used the injectable for ten years without problems, but was recently noticing an increase in pain following the injection. Now though I have had an injection site reaction where there is a fairly large bright red area that is very itchy and hard. It is not terribly painful, but perhaps just past the liminal level of pain. I have also had smaller pinpoint red marks from other recent injections. I had not thought that it could be a reaction to the preserving agent.
Rose @}>->-- Being educated means that rather than fearing the unknown, one seeks to understand it. RB
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