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Medical Forum / Diseases and Disorders / Arthritis / March 2005Glucosamine and bleeding
I note at one on-line site it says: "If you are taking chondroitin or glucosamine sulfate in addition to a blood-thinning medication or daily aspirin therapy, have your blood clotting time checked more often. This supplement is similar in structure to the blood-thinning drug heparin, and the combination may cause bleeding in some people." I've been taking glucosamine for some ten days now and, for the first time, noticed a trace of blood in my saliva first thing this morning. It might be coming from the back of my nose. I've been taking a baby aspirin every day for years now. The bleeding seems to have stopped now, a few hours later. What do you think? Stop the glucosamine or the aspirin? Cut back on aspirin to a half or every other day? The glucosamine seems to be helping my osteo- arthritis so I am reluctant to stop it. Last night I took a couple of Excedrin for a headache too, something I rarely do. Too much on top of the daily aspirin and glocosamine? Finally, I'm recovering from a cold as well. Thoughts, anyone? TIA  SignatureUntie the two knots to email me "Madness is not a consequence of uncertainty, but of certainty." Nietzche call your doctor asap. you might have a sinus infection. or, you might be having a reaction to the combination of things you are taking. or it might be nothing. better to ask your doctor and have him/her figure it out. kate >I note at one on-line site it says: > [quoted text clipped - 22 lines] > > TIA > I note at one on-line site it says: > [quoted text clipped - 3 lines] > structure to the blood-thinning drug heparin, and the combination may > cause bleeding in some people." I'm very interested to know more details about this, but I have never heard anything of the sort about glucosamine and I suspect that this is an unsubstatiated claim on the website you came across. Which website was it printed on? > I've been taking glucosamine for some ten days now and, for the first > time, noticed a trace of blood in my saliva first thing this morning. It [quoted text clipped - 14 lines] > > TIA Signaturespammage trappage: replace fishies_ with yahoo I'm going to die rather sooner than I'd like. I tried to protect my neighbours from crime, and became the victim of it. Complications in hospital following this resulted in a serious illness. I now need a bone marrow transplant. Many people around the world are waiting for a marrow transplant, too. Please volunteer to be a marrow donor: http://www.abmdr.org.au/ http://www.marrow.org/ It seems to me I heard somewhere that spodosaurus wrote in article <423f112e$1@quokka.wn.com.au>: >> I note at one on-line site it says: >> "If you are taking chondroitin or glucosamine sulfate in addition to a >> blood-thinning medication or daily aspirin therapy, have your blood >> clotting time checked more often. This supplement is similar in >> structure to the blood-thinning drug heparin, and the combination may >> cause bleeding in some people." >I'm very interested to know more details about this, but I have never >heard anything of the sort about glucosamine and I suspect that this is >an unsubstatiated claim on the website you came across. Which website >was it printed on? I'll chime in along the same lines. My first cardiologist started me on statins (currently Lipitor 80mg), and the next one soon after started me on aspirin 325mg. Two or three years ago I added glucosamine/chondroitin (typically 1000mg-1500mg glucosamine) with the knowledge of my PCP. None of them warned me, nor have I seen anything in writing about potential problems caused by the combination. Hopefully you can discuss it with your doctor and set you mind at ease. >> I've been taking glucosamine for some ten days now and, for the first >> time, noticed a trace of blood in my saliva first thing this morning. It >> might be coming from the back of my nose. I've been taking a baby >> aspirin every day for years now. The bleeding seems to have stopped now, >> a few hours later. >> What do you think? Stop the glucosamine or the aspirin? Cut back on >> aspirin to a half or every other day? The glucosamine seems to be >> helping my osteo- arthritis so I am reluctant to stop it. >> Last night I took a couple of Excedrin for a headache too, something I >> rarely do. Too much on top of the daily aspirin and glocosamine? >> Finally, I'm recovering from a cold as well. >> Thoughts, anyone? SignatureDon Old age is when you start saying "I wish I knew now what I knew then." I don't recall. It was was one of the first ones I came to in Google searching on glucosamine sulfate. Ken spodosaurus <spodosaurus@_yahoo_.com> wrote in news:423f112e$1 @quokka.wn.com.au: > I'm very interested to know more details about this, but I have never > heard anything of the sort about glucosamine and I suspect that this is > an unsubstatiated claim on the website you came across. Which website > was it printed on? SignatureUntie the two knots to email me "Madness is not a consequence of uncertainty, but of certainty." Nietzche > I note at one on-line site it says: > [quoted text clipped - 3 lines] > structure to the blood-thinning drug heparin, and the combination may > cause bleeding in some people." I've done some research, and this claim seems wrong. From what I understand, heparin (there are many heparinoid compounds) is made from long chains of glucosamine of slightly different chemical structures. I don't see supplemental glucosamine magically turning into heparin, though. I've come across some speculation that there might be an interaction between heparin and chondroitin or glucosamine, but nothing remotely substantiated. I'll ask my haematologist on Thursday if he has heard anything like this. > I've been taking glucosamine for some ten days now and, for the first > time, noticed a trace of blood in my saliva first thing this morning. It [quoted text clipped - 14 lines] > > TIA Signaturespammage trappage: replace fishies_ with yahoo I'm going to die rather sooner than I'd like. I tried to protect my neighbours from crime, and became the victim of it. Complications in hospital following this resulted in a serious illness. I now need a bone marrow transplant. Many people around the world are waiting for a marrow transplant, too. Please volunteer to be a marrow donor: http://www.abmdr.org.au/ http://www.marrow.org/ >> I note at one on-line site it says: >> [quoted text clipped - 12 lines] > remotely substantiated. I'll ask my haematologist on Thursday if he has > heard anything like this. I'd like to add to my post. Since restarting the glucosamine a couple of weeks ago, I've seen an increase in petechia and bruising. My extremely low platelet counts are still in the same extremely low range. I have been sick from at least one viral infection during this time and there have been other medication changes, so keep this in mind. However, I have to wonder, does glucosamine in even very short polymers have a heparin like effect, and are these very short polymers present in over the counter glucosamine supplements? For me in particular, these are VERY important questions. I'm going to speak with my doctor about this and do some further research. Until then, I'm discontinuing my glucosamine hydrochloride supplementation. Ari Signaturespammage trappage: replace fishies_ with yahoo I'm going to die rather sooner than I'd like. I tried to protect my neighbours from crime, and became the victim of it. Complications in hospital following this resulted in a serious illness. I now need a bone marrow transplant. Many people around the world are waiting for a marrow transplant, too. Please volunteer to be a marrow donor: http://www.abmdr.org.au/ http://www.marrow.org/ Ken, It might be from your sinusis. Need to call your doc to make sure though. I wouldn't panic yet. debbie m. http://www.angelfire.com/ga2/angels1/ > I note at one on-line site it says: > [quoted text clipped - 28 lines] > "Madness is not a consequence of uncertainty, but of certainty." > Nietzche As I posted, the bleeding stopped, and hasn't resumed. I'm not going to the doctor about a few drops of blood. I've had much much worse without a visit and survived. I can't afford all the blood tests and specialist visits they usually entail. I very very rarely go to the doctor. Haven't been in many years. Things usually resolve themselves. > It might be from your sinusis. Need to call your doc to make sure > though. I wouldn't panic yet. SignatureUntie the two knots to email me "Madness is not a consequence of uncertainty, but of certainty." Nietzche > I note at one on-line site it says: What site is that? > noticed a trace of blood in my saliva first thing this morning. > What do you think? Call your doctor about your concerns. > Finally, I'm recovering from a cold as well. > > Thoughts, anyone? I'll repeat (as other probably will): Call your doctor. |
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