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Medical Forum / Diseases and Disorders / Arthritis / December 2004

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Food and Drug Administration

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RA-5C - 21 Dec 2004 02:55 GMT
I just hope that there will be a a through investigation into the Food
and Drug Administration. There are far to many individuals that are
suffering from arthritis in this country. We have depended on the FDA to
license and regulate the drug industry and to ensure that we were
getting the best and safest medicine that is possible. And it is
beginning to look as though they have failed us.
RhondaM - 21 Dec 2004 03:23 GMT
They have.. It is like to give hope and yank it away.
I think this is just the beginning next it will be Biologicals.

>I just hope that there will be a a through investigation into the Food
> and Drug Administration. There are far to many individuals that are
> suffering from arthritis in this country. We have depended on the FDA to
> license and regulate the drug industry and to ensure that we were
> getting the best and safest medicine that is possible. And it is
> beginning to look as though they have failed us.
Harvey R. Stone - 21 Dec 2004 04:25 GMT
> They have.. It is like to give hope and yank it away.
> I think this is just the beginning next it will be Biologicals.

Well, aren't we just a bundle of good will and better tomorrows.    I do not
agree with what you have said.   I do not agree with even saying it.   How
about a nice put down before Christmas???  What do ya say?
Harv
RhondaM - 21 Dec 2004 04:49 GMT
no I am saying that I am frustrated with the FDA not the poster.. sorry if
it seems that way. I am really upset about all the controversy with the
NSAIDS. Not the messenger.
If you know me I am not a negative person nor do I put down people please
don't think that ok?

>> They have.. It is like to give hope and yank it away.
>> I think this is just the beginning next it will be Biologicals.
[quoted text clipped - 3 lines]
> How about a nice put down before Christmas???  What do ya say?
> Harv
Harvey R. Stone - 21 Dec 2004 09:20 GMT
> no I am saying that I am frustrated with the FDA not the poster.. sorry if
> it seems that way. I am really upset about all the controversy with the
> NSAIDS. Not the messenger.
> If you know me I am not a negative person nor do I put down people please
> don't think that ok?

In all of what we have read ties anti-tnfs with any of it.   Why should we
put doubt in peoples minds with a guilt by associations assumption about the
FDA.
Harv
Newsgroup Spambuster - 21 Dec 2004 07:30 GMT
Harv,

Is everything OK on your end?   Are you feeling alright?    Something is
just not ringing right with some of your posts lately.   They seem a bit
harsh for you.   Is there anything we can do to help ease what ever is
going on???    Praying that you are really ok!!!

Donna G
d'huit - 21 Dec 2004 09:15 GMT
> Harv,
>
[quoted text clipped - 4 lines]
>
> Donna G

thank you for this, donnag.  i was wondering the same thing and wondering
if, because he's on that tb med, that his arthritis meds are not allowed,
which would be a major owie.

kate
Harvey R. Stone - 21 Dec 2004 10:28 GMT
> Harv,
>
[quoted text clipped - 4 lines]
>
> Donna G

Thank you and I need those prayers.   No,  I am not OK and I am not to nice
a person when life steps on me enough but in all truth,,,, there are a few
things going across our boards that would bother me even if things were
going just great.  Not going to do a rant here,,, it does not do any good
for anyone.
    No,,, there is nothing else you can do.     I have TB Donna.   I think
it is all over my body without having any nodules in my lungs and there is
no sign that I have ever been able to infect anyone else.  The medicine I
take is Isoniazid for me it is like 30 mg of Methx would be,,, I guess.  I
am caught in a catch 22 that I do not see anyway out of.   This medicine has
to have a kind of diet that means a person can eat or take anything with
histamines in it.    I am having a reaction to Remicade with a rash that
itches like fire across the small of my back and up my backbone.  I have no
idea why it is there and not somewhere else.   Do you know I have to take to
control that?  Antihistamine,,,, and Allergra.   The rash gets better and I
feel like crap(the Methx comparison).  I have had to cancel my next
appointment for an infusion.  Do you know what kind of mental stress goes
with stopping a DMARD?   To be honest, it is much like the way all the
people that are giving up their OA medicines,,,Bextra, Vioxx, and Celebrex
and now they are trying to add Naproxyn.   I just put my youngest daughter
on to Aleve for her Corp-tunnel
which has both of her hands in braces when she is in her last year of her
doctors and needs to publish. Her doctor in England has put her on whapper
ibuesss three times a day and she did not bring enough to cover her visit.
I TOOK 3-500MG NAPROSYN FOR 6 YEARS BEFORE I SAW MY FIRST RD.  The look on
her face when on CNN they talked about Aleve and/or Naprosyn.   My blood
pressure in normal resting is 120/80 with no complications shown during a
stress test.   As I write all this and read your words,  I think I am
getting stressed out seeing those braces on my daughters arms and my best
advice with what has worked so well for me over the years does not look good
up against,,,, CNN.
      But to get back to the TB and my RA,,,,,, the reaction, the diet and
the catch 22 on what it takes to control the rash has me typing this at
400AM and realizing that I may be,,,,, am taking it out on others,,
WHO JUST MAY Need IT.   I am going to gone from the newsgroup for quite
awhile but I want to leave on a positive note that I can not prove.    I
really believe that my wild immune system took off on me at the age of 38
when I Might of been exposed to TB.    8 months from now when all the TB is
gone and I have driven my wife crazy.     I finally took Elf/ Marge's advice
with the anti-biotic treatment with an anti-biotic a whole lot stronger than
Tetracycline(sp).     I will be cured.   I am 65 and it would be nice to
have my remaining years without the pain and swelling that goes with what
everyone thought was RA.
I am going to try to think this way and it will help me get through the next
months and no one here is going to have to pay for my stress and pain if I
go into a flare and no DMARD.
May God bless everyone of you and your friends and family.   Please take a
little time to remember that this time of the year is about New Beginnings
in Christ with a Happy New Year to follow.  With the Lords help,,,, it will
be a good year for all of us.   Lets be positive and make it that way.
Harv
d'huit - 21 Dec 2004 10:54 GMT
{{{{{{{{{{{{{{{{{{{{{harv}}}}}}}}}}}}}}}}}}}}}}  god bless you, guy.  i just
knew it had to be something like this contributing.  i wish i knew some
instantaneous magical thing that would be of help to you, but i am neither
magical, nor knowledgible about these kinds of things.  wish i knew some
wise words that would help you feel better about it all.   i'm sure your
wife really does understand that it is the disease.  she might just need a
little break now and then, like i did with butch.  can your daughter's
doctor prescribe a good anti-inflamatory, like relafen for her?  i know that
one really helped me with tendons (and bursa) inflammations.  as you already
know, carpal tunnel is an inflamed tendon issue.

you are and will continue to be in my prayers for relief for you and healing
thoughts for you, harv.  and please try not to be too hard on yourself, guy,
cuz i care about you.

kate

>> Harv,
>>
[quoted text clipped - 57 lines]
> way.
> Harv
Janet R - 21 Dec 2004 14:44 GMT
Harv...sent ya an email.

Janet R

| > Harv,
| >
[quoted text clipped - 56 lines]
| be a good year for all of us.   Lets be positive and make it that way.
| Harv
DCHAM - 21 Dec 2004 19:56 GMT
harv, i'm sorry you're going through all this. the uncertainty has to be very
scary. i hope you won't leave (tho please do sit on your hands when you're
temped to write something hurtful to someone!). people care about you here, and
this is not a great time to cut yourself off from support.

diane
d'huit - 21 Dec 2004 09:22 GMT
> They have.. It is like to give hope and yank it away.
> I think this is just the beginning next it will be Biologicals.

i think we need to stay calm about this, allow the FDA to do their work, and
not jump to conclusions before the FDA is finished with their investigating.
sweetie, try not to read this particular poster's (RA-5C) threads.  it
appears that he tends to enjoy stirring up people's emotions/pushing
emotional buttons.  not a good poster to read, if one is feeling
particularly vulnerable.

kate

>>I just hope that there will be a a through investigation into the Food
>> and Drug Administration. There are far to many individuals that are
>> suffering from arthritis in this country. We have depended on the FDA to
>> license and regulate the drug industry and to ensure that we were
>> getting the best and safest medicine that is possible. And it is
>> beginning to look as though they have failed us.
spodosaurus - 21 Dec 2004 05:27 GMT
> I just hope that there will be a a through investigation into the Food
> and Drug Administration. There are far to many individuals that are
> suffering from arthritis in this country. We have depended on the FDA to
> license and regulate the drug industry and to ensure that we were
> getting the best and safest medicine that is possible. And it is
> beginning to look as though they have failed us.

Sometimes effects of drugs on the *population* only come to light over
time. Increasing the number of studies required increases the time
patients have to wait, sometimes for life saving medications. I'm still
waiting for all the facts to come out in the Vioxx issue, but Celebrex
is a measured risk according to one study, and not a risk according to
another. More work is needed. In the mean time, people can make a
decision based on potential risk and weight that up against quality of
life benefits.

Cheers,

Ari

Signature

spammage trappage: replace fishies_ with yahoo

I'm going to die rather sooner than I'd like. I tried to protect my
neighbours from crime, and became the victim of it. To jump to the end
of the story, as a result of this I need a bone marrow transplant. Many
people around the world are waiting for a marrow transplant, too. Please
volunteer to be a marrow donor:
http://www.abmdr.org.au/
http://www.marrow.org/

Harvey R. Stone - 21 Dec 2004 09:24 GMT
> Sometimes effects of drugs on the *population* only come to light over
> time. Increasing the number of studies required increases the time
[quoted text clipped - 4 lines]
> based on potential risk and weight that up against quality of life
> benefits. Cheers,

> Ari

That is soooo well said.   The truth of it is that the lawyers are to take
your ability to make choices,, decisions about your medicine away from you
and your doctor.
Harv
spodosaurus - 21 Dec 2004 10:05 GMT
>>Sometimes effects of drugs on the *population* only come to light over
>>time. Increasing the number of studies required increases the time
[quoted text clipped - 11 lines]
> and your doctor.
> Harv

My physiotherapist made a similar comment about it being in the hands of
the lawyers :-(

Signature

spammage trappage: replace fishies_ with yahoo

I'm going to die rather sooner than I'd like. I tried to protect my
neighbours from crime, and became the victim of it. To jump to the end
of the story, as a result of this I need a bone marrow transplant. Many
people around the world are waiting for a marrow transplant, too. Please
volunteer to be a marrow donor:
http://www.abmdr.org.au/
http://www.marrow.org/

RhondaM - 21 Dec 2004 17:25 GMT
I have noticed there has been allot of "New" posters concerning the
Vioxx/Celebrex stuff. Lawyers???? The bad kind that prey on peoples
emotions? I should be smart enough to see through this..
(((((((((((((((((((((HARV)))))))))))))))))) I think the world about you and
I wish you a Merry Christmas and all the joy and happiness that comes with
it!
RhondaM

>>>Sometimes effects of drugs on the *population* only come to light over
>>>time. Increasing the number of studies required increases the time
[quoted text clipped - 14 lines]
> My physiotherapist made a similar comment about it being in the hands of
> the lawyers :-(
RoseB - 21 Dec 2004 17:44 GMT
>I have noticed there has been allot of "New" posters concerning the
>Vioxx/Celebrex stuff. Lawyers????

It is interesting. About a month ago I did a search to see if celebrex
was implicated as causing heart problems in a similar way that vioxx
was purported to do. The only information I found then was on lawyers'
websites. That is not to say that I condemn all lawyers; we have some
in our family and there are some others that I know and love dearly.
Those partcular lawyers were spreading mis-information even before
these current test results came to light.

What is significant to me is that the porblems occured most frequently
in dosages of 800 mg per day, which is double what is recommended for
arthritis. It is somewhat understandable that such a high dose would
create problems, I would suspect there would be liver toxicity as
well, in terms of the body's ability to clear that much drug from the
system. Having said that though, I do believe that all drugs have
risks, that a person has to weigh the benefits against the risks, and
decide accordingly. We need to be informed consumers of everything we
put into our bodies.

And yes, I am a celebrex user, in addition to remicade and
methotrexate. So according to the latest study info that has been
brought to light am at increased risk for lymphoma, heart problems,
and liver complications. It is a risk I take because to not take it
means that there is no quality of life at all. I have been at that
state for very many years, and so the relief that is offered by the
new drugs is a welcome respite from debilitating pain and no life at
all really.

    Rose   @}>->--
    Being educated means that rather than fearing the unknown, one seeks to understand it. RB

    Please remove "Ima" to reply.
 
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