Medical Forum / Diseases and Disorders / Arthritis / December 2004
Food and Drug Administration
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RA-5C - 21 Dec 2004 02:55 GMT I just hope that there will be a a through investigation into the Food and Drug Administration. There are far to many individuals that are suffering from arthritis in this country. We have depended on the FDA to license and regulate the drug industry and to ensure that we were getting the best and safest medicine that is possible. And it is beginning to look as though they have failed us.
RhondaM - 21 Dec 2004 03:23 GMT They have.. It is like to give hope and yank it away. I think this is just the beginning next it will be Biologicals.
>I just hope that there will be a a through investigation into the Food > and Drug Administration. There are far to many individuals that are > suffering from arthritis in this country. We have depended on the FDA to > license and regulate the drug industry and to ensure that we were > getting the best and safest medicine that is possible. And it is > beginning to look as though they have failed us. Harvey R. Stone - 21 Dec 2004 04:25 GMT > They have.. It is like to give hope and yank it away. > I think this is just the beginning next it will be Biologicals. Well, aren't we just a bundle of good will and better tomorrows. I do not agree with what you have said. I do not agree with even saying it. How about a nice put down before Christmas??? What do ya say? Harv
RhondaM - 21 Dec 2004 04:49 GMT no I am saying that I am frustrated with the FDA not the poster.. sorry if it seems that way. I am really upset about all the controversy with the NSAIDS. Not the messenger. If you know me I am not a negative person nor do I put down people please don't think that ok?
>> They have.. It is like to give hope and yank it away. >> I think this is just the beginning next it will be Biologicals. [quoted text clipped - 3 lines] > How about a nice put down before Christmas??? What do ya say? > Harv Harvey R. Stone - 21 Dec 2004 09:20 GMT > no I am saying that I am frustrated with the FDA not the poster.. sorry if > it seems that way. I am really upset about all the controversy with the > NSAIDS. Not the messenger. > If you know me I am not a negative person nor do I put down people please > don't think that ok? In all of what we have read ties anti-tnfs with any of it. Why should we put doubt in peoples minds with a guilt by associations assumption about the FDA. Harv
Newsgroup Spambuster - 21 Dec 2004 07:30 GMT Harv,
Is everything OK on your end? Are you feeling alright? Something is just not ringing right with some of your posts lately. They seem a bit harsh for you. Is there anything we can do to help ease what ever is going on??? Praying that you are really ok!!!
Donna G
d'huit - 21 Dec 2004 09:15 GMT > Harv, > [quoted text clipped - 4 lines] > > Donna G thank you for this, donnag. i was wondering the same thing and wondering if, because he's on that tb med, that his arthritis meds are not allowed, which would be a major owie.
kate
Harvey R. Stone - 21 Dec 2004 10:28 GMT > Harv, > [quoted text clipped - 4 lines] > > Donna G Thank you and I need those prayers. No, I am not OK and I am not to nice a person when life steps on me enough but in all truth,,,, there are a few things going across our boards that would bother me even if things were going just great. Not going to do a rant here,,, it does not do any good for anyone. No,,, there is nothing else you can do. I have TB Donna. I think it is all over my body without having any nodules in my lungs and there is no sign that I have ever been able to infect anyone else. The medicine I take is Isoniazid for me it is like 30 mg of Methx would be,,, I guess. I am caught in a catch 22 that I do not see anyway out of. This medicine has to have a kind of diet that means a person can eat or take anything with histamines in it. I am having a reaction to Remicade with a rash that itches like fire across the small of my back and up my backbone. I have no idea why it is there and not somewhere else. Do you know I have to take to control that? Antihistamine,,,, and Allergra. The rash gets better and I feel like crap(the Methx comparison). I have had to cancel my next appointment for an infusion. Do you know what kind of mental stress goes with stopping a DMARD? To be honest, it is much like the way all the people that are giving up their OA medicines,,,Bextra, Vioxx, and Celebrex and now they are trying to add Naproxyn. I just put my youngest daughter on to Aleve for her Corp-tunnel which has both of her hands in braces when she is in her last year of her doctors and needs to publish. Her doctor in England has put her on whapper ibuesss three times a day and she did not bring enough to cover her visit. I TOOK 3-500MG NAPROSYN FOR 6 YEARS BEFORE I SAW MY FIRST RD. The look on her face when on CNN they talked about Aleve and/or Naprosyn. My blood pressure in normal resting is 120/80 with no complications shown during a stress test. As I write all this and read your words, I think I am getting stressed out seeing those braces on my daughters arms and my best advice with what has worked so well for me over the years does not look good up against,,,, CNN. But to get back to the TB and my RA,,,,,, the reaction, the diet and the catch 22 on what it takes to control the rash has me typing this at 400AM and realizing that I may be,,,,, am taking it out on others,, WHO JUST MAY Need IT. I am going to gone from the newsgroup for quite awhile but I want to leave on a positive note that I can not prove. I really believe that my wild immune system took off on me at the age of 38 when I Might of been exposed to TB. 8 months from now when all the TB is gone and I have driven my wife crazy. I finally took Elf/ Marge's advice with the anti-biotic treatment with an anti-biotic a whole lot stronger than Tetracycline(sp). I will be cured. I am 65 and it would be nice to have my remaining years without the pain and swelling that goes with what everyone thought was RA. I am going to try to think this way and it will help me get through the next months and no one here is going to have to pay for my stress and pain if I go into a flare and no DMARD. May God bless everyone of you and your friends and family. Please take a little time to remember that this time of the year is about New Beginnings in Christ with a Happy New Year to follow. With the Lords help,,,, it will be a good year for all of us. Lets be positive and make it that way. Harv
d'huit - 21 Dec 2004 10:54 GMT {{{{{{{{{{{{{{{{{{{{{harv}}}}}}}}}}}}}}}}}}}}}} god bless you, guy. i just knew it had to be something like this contributing. i wish i knew some instantaneous magical thing that would be of help to you, but i am neither magical, nor knowledgible about these kinds of things. wish i knew some wise words that would help you feel better about it all. i'm sure your wife really does understand that it is the disease. she might just need a little break now and then, like i did with butch. can your daughter's doctor prescribe a good anti-inflamatory, like relafen for her? i know that one really helped me with tendons (and bursa) inflammations. as you already know, carpal tunnel is an inflamed tendon issue.
you are and will continue to be in my prayers for relief for you and healing thoughts for you, harv. and please try not to be too hard on yourself, guy, cuz i care about you.
kate
>> Harv, >> [quoted text clipped - 57 lines] > way. > Harv Janet R - 21 Dec 2004 14:44 GMT Harv...sent ya an email.
Janet R
| > Harv, | > [quoted text clipped - 56 lines] | be a good year for all of us. Lets be positive and make it that way. | Harv DCHAM - 21 Dec 2004 19:56 GMT harv, i'm sorry you're going through all this. the uncertainty has to be very scary. i hope you won't leave (tho please do sit on your hands when you're temped to write something hurtful to someone!). people care about you here, and this is not a great time to cut yourself off from support.
diane
d'huit - 21 Dec 2004 09:22 GMT > They have.. It is like to give hope and yank it away. > I think this is just the beginning next it will be Biologicals. i think we need to stay calm about this, allow the FDA to do their work, and not jump to conclusions before the FDA is finished with their investigating. sweetie, try not to read this particular poster's (RA-5C) threads. it appears that he tends to enjoy stirring up people's emotions/pushing emotional buttons. not a good poster to read, if one is feeling particularly vulnerable.
kate
>>I just hope that there will be a a through investigation into the Food >> and Drug Administration. There are far to many individuals that are >> suffering from arthritis in this country. We have depended on the FDA to >> license and regulate the drug industry and to ensure that we were >> getting the best and safest medicine that is possible. And it is >> beginning to look as though they have failed us. spodosaurus - 21 Dec 2004 05:27 GMT > I just hope that there will be a a through investigation into the Food > and Drug Administration. There are far to many individuals that are > suffering from arthritis in this country. We have depended on the FDA to > license and regulate the drug industry and to ensure that we were > getting the best and safest medicine that is possible. And it is > beginning to look as though they have failed us. Sometimes effects of drugs on the *population* only come to light over time. Increasing the number of studies required increases the time patients have to wait, sometimes for life saving medications. I'm still waiting for all the facts to come out in the Vioxx issue, but Celebrex is a measured risk according to one study, and not a risk according to another. More work is needed. In the mean time, people can make a decision based on potential risk and weight that up against quality of life benefits.
Cheers,
Ari
 Signature spammage trappage: replace fishies_ with yahoo
I'm going to die rather sooner than I'd like. I tried to protect my neighbours from crime, and became the victim of it. To jump to the end of the story, as a result of this I need a bone marrow transplant. Many people around the world are waiting for a marrow transplant, too. Please volunteer to be a marrow donor: http://www.abmdr.org.au/ http://www.marrow.org/
Harvey R. Stone - 21 Dec 2004 09:24 GMT > Sometimes effects of drugs on the *population* only come to light over > time. Increasing the number of studies required increases the time [quoted text clipped - 4 lines] > based on potential risk and weight that up against quality of life > benefits. Cheers,
> Ari That is soooo well said. The truth of it is that the lawyers are to take your ability to make choices,, decisions about your medicine away from you and your doctor. Harv
spodosaurus - 21 Dec 2004 10:05 GMT >>Sometimes effects of drugs on the *population* only come to light over >>time. Increasing the number of studies required increases the time [quoted text clipped - 11 lines] > and your doctor. > Harv My physiotherapist made a similar comment about it being in the hands of the lawyers :-(
 Signature spammage trappage: replace fishies_ with yahoo
I'm going to die rather sooner than I'd like. I tried to protect my neighbours from crime, and became the victim of it. To jump to the end of the story, as a result of this I need a bone marrow transplant. Many people around the world are waiting for a marrow transplant, too. Please volunteer to be a marrow donor: http://www.abmdr.org.au/ http://www.marrow.org/
RhondaM - 21 Dec 2004 17:25 GMT I have noticed there has been allot of "New" posters concerning the Vioxx/Celebrex stuff. Lawyers???? The bad kind that prey on peoples emotions? I should be smart enough to see through this.. (((((((((((((((((((((HARV)))))))))))))))))) I think the world about you and I wish you a Merry Christmas and all the joy and happiness that comes with it! RhondaM
>>>Sometimes effects of drugs on the *population* only come to light over >>>time. Increasing the number of studies required increases the time [quoted text clipped - 14 lines] > My physiotherapist made a similar comment about it being in the hands of > the lawyers :-( RoseB - 21 Dec 2004 17:44 GMT >I have noticed there has been allot of "New" posters concerning the >Vioxx/Celebrex stuff. Lawyers???? It is interesting. About a month ago I did a search to see if celebrex was implicated as causing heart problems in a similar way that vioxx was purported to do. The only information I found then was on lawyers' websites. That is not to say that I condemn all lawyers; we have some in our family and there are some others that I know and love dearly. Those partcular lawyers were spreading mis-information even before these current test results came to light.
What is significant to me is that the porblems occured most frequently in dosages of 800 mg per day, which is double what is recommended for arthritis. It is somewhat understandable that such a high dose would create problems, I would suspect there would be liver toxicity as well, in terms of the body's ability to clear that much drug from the system. Having said that though, I do believe that all drugs have risks, that a person has to weigh the benefits against the risks, and decide accordingly. We need to be informed consumers of everything we put into our bodies.
And yes, I am a celebrex user, in addition to remicade and methotrexate. So according to the latest study info that has been brought to light am at increased risk for lymphoma, heart problems, and liver complications. It is a risk I take because to not take it means that there is no quality of life at all. I have been at that state for very many years, and so the relief that is offered by the new drugs is a welcome respite from debilitating pain and no life at all really.
Rose @}>->-- Being educated means that rather than fearing the unknown, one seeks to understand it. RB
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