Hi, I don't have arthritis per se, but due to my search, perhaps this is the
best group to ask due to the numbers of people here using Bextra or
Naproxyn.
I was in a bad car accident four and a half years ago, and suffered a broken
left femur, and now have a titanium rod there. Also had a broken right tibia
which healed, and a torn meniscus on my right knee which the hospital never
repaired, and which I don't have the money to take care of. I'm not sure
which part of the right knee meniscus is torn, as I hear there's more than
one meniscus, or parts thereof.
In my work, and daily activities, I often get pain around the torn meniscus
area and sometimes around where my femur was broke. I believe I can
generally put just so much stress a day on this, as it's usually fine until
a certain point of use/stress. Then the areas get tender and some pain. Not
excruciating, but just enough that I take as a warning sign to slow down any
activities using my legs and let them recuperate. I don't feel like putting
more stress, not only the pain, but I fear I may injure the stressed areas
more.
I expressed this to my doctor, as my job has gotten harder and tougher, more
on my legs, and therefore more stress. A couple weeks ago she gave me a 14
day sample supply of Bextra 10 mg tabs, and told me to take one a day, every
day, no matter if my legs bother me or not.
The next day it was all over the news of the reports on how Vioxx and it's
relatives, including Bextra are causing heart attacks and strokes. I waited
until last week until I started taking them, knowing I had another doctors
appointment this week, and I figured give it a try, and I shouldn't drop
dead in a week. The Bextra seem to work pretty good so far. I still feel a
little pain in my legs at times, but I think the frequency is much reduced.
At my appointment Monday, I brought up the reports linking Vioxx/Bextra with
heart attacks, etc. My doctor said I could try something else if I'm that
concerned, so she prescribed me Naproxyn 375 mg twice a day. I got if
filled, and when I got home, went online and read to pretty much expect
ulcers and other gastric troubles if taking Naproxyn. In fact one website
claims a 72% rate of users who use Naproxyn to get ulcers. I really don't
know in what kind of time frame, but I will probably be on whatever I have
to take indefinitely, so I don't want to deal with ulcers.
I'm a reasonably healthy 51 year old white male with average blood pressure,
usually around 110/80. I don't smoke and never have, I'll occasionally drink
socially. I just had stress tests done for my heart last May, and they said
my heart was fine, and I have had no heart disease or any symptoms in that
area to worry about getting checked out. I am taking Gemfibrozil (Lopid) to
lower my triglyceride count, or else it would be sky high. It's still a
little high, but nothing compared to what it would be without the Lopid. My
cholesterol can be a little high also, with good cholesterol low, and bad
cholesterol on the high side. She may give me something else in the future
to help this. My digestive health seems OK, but I do believe I get
occasional acid reflux. I believe my kidneys are OK, but have had some past
liver problems, but tests are OK last few years.
I know if I stay with Naproxyn, I will probably eventually get ulcers. I
would be tempted to stick with the Bextra, as my heart seems healthy right
now. Anybody in the medical profession want to offer a "non-legally biding
for advice only" second opinion? And why can't I just take whatever I get
prescribed just when I need it, or think I'll need it, say I know I'll have
a long work day and take it before hand? Instead of every day. Sorry so
long, thanks much,
Dan
--
Nicole H - 10 Dec 2004 13:50 GMT
According to my doctor, Bextra is safe if your blood pressure is monitored.
Once you start the med, you need to go back for follow up.
All NSAIDs inhibit cox 2 so I'm not sure why Vioxx, Bextra and Celebrex are
supposed to be more dangerous.
If Naproxen works, use it. Just make sure you do something to protect your
stomach. I used to take high doses of naproxen or ibuprofen and got an
ulcer from it. I then switched to Arthrotec-diclofenac sodium and
misoprostol. The misoprostol (cytotec) protects your stomach.
If your insurance won't cover Arthrotec, ask your doctor about rx'ing
misoprostol along w/the naproxen to help prevent stomach ulcers.
I use bextra right now along with Protonix and occasionally Zantac 150 bid.
HTH
Nicole
Harvey R. Stone - 10 Dec 2004 14:06 GMT
> Hi, I don't have arthritis per se, but due to my search, perhaps this is
> the
> best group to ask due to the numbers of people here using Bextra or
> Naproxyn.
>
> Dan
Hi Dan,, Bextra is a different class of drug than Naproxyn.
I took prescription Naproxyn @ 3/day/500mg for 6 years with having an
ulcer problem. You are going to take 375/twice a day. The thing is that
with all the information coming out about Bextra, I would not start it.
You could get ulcers next week with your dosage of Naproxyn
but that may not happen AND you have to do something.
Harv
Nann Bell - 10 Dec 2004 14:56 GMT
Naprosyn *may* cause stomach problems, but it isn't for certain that it will,
no matter how long you take it. Bextra is from a new class of drugs that is
less likely to cause stomcah problems, but some people still do have trouble.
People just do react differently to different meds.
You can greatly reduce your risk of developing ulcers on Naprosyn by always
taking it with food or with a glass of juice/milk/something of that ilk.
That helps protect your stomach. There are also medications you can take to
help your stomach, as someone else has mentioned. You and your doctor should
consult and decide which is the greater and more important risk factor for
you. Oh, and one issue is the differing age of the meds. Naprosyn has been
out and in use for at least a couple of decades so its risks are well-known.
Bextra has only been out for a few years so its risks are not as clearly
determined.
When doctors have you take a non-steroidal anti-inflammatory drug (aka NSAID)
on a daily basis, regardless of your pain level, the aim is to treat an
underlying inflammatory condition. By taking it on a routine basis, you are
(hopefully) *preventing* the inflammation rezching the point where the pain
kicks in. If you only take the NSAID when your leg hurts, there is already a
fair amount of inflammation present. Inflammation can degrade tendons and
cartilage, so it is best to prevent it whenever possible. There may be other
considerations for it in treating your torn miniscus, I just don't know on
that front.
A couple of other points - you will most certainly have the option of
changing meds in the future. Pharmaceutical companies are always researching
new NSAIDs. There will be more on the market in coming years, so you may not
have to take either one for all that many years. Another possibility is
Celebrex, whichis in the same class of NSAIDs as Bextra and so far has no
suspicions of heart trouble associated with it. It'd be a good idea to
discuss the options and weight the pros and cons with your doc.
Oh, and was the torn meniscus from your car accident? If so, it seems your
car insurance should pay for it, even several years later. Might be worth
asking them about.

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