This is my own anecdotal experience. I am not a doctor and this is not
intended to be medical advice.
I always thought that there was a connection in-between the food that I ate
and my psoriatic arthritis. The food that would aggravate my symptoms the
most was pizza - my psoriasis and arthritis would flare up dramatically the
next day.
At first I thought that the pizza sauce was the culprit; I had previously
read about some people being allergic to the nightshade vegetables so I cut
them out. It did nothing for me.
I then started on Enbrel after failing methotrexate and it was like a
miracle for me. At one point, about four years ago, I could hardly walk.
After being on Enbrel for four months, my joint inflammation was normal.
I was taking Enbrel twice weekly for about a year. The inflammation in my
joints was no longer there, but I still had the psoriasis.
Six months ago, I tried the Paleolithic diet which consists of fresh meat,
fruit and vegetables. Amazingly enough, my stubborn psoriasis patches
started to clear up. These are patches that 3 years of Enbrel,
methotrextate, prednisone and topical steroids (not all at once) failed to
clear up.
It occurred to me that it might be the gluten in the pizza that caused the
reaction. I experimented by adding foods back into my diet. I discovered
that both gluten and red meat (beef and lamb) cause a reaction. I also
noticed that my digestive system works better when I avoid these foods.
After cutting out these foods (avoiding gluten basically means that you have
to cook most meals yourself), I was able to reduce my input of Enbrel
dramatically. I am currently using Enbrel only twice a month, usually to
combat accidental gluten ingestion. I have almost no psoriasis, no joint
inflammation and my skin feels healthy.
My hypothesis is that I have a food allergy which promotes my immune system
to attack my intestine. After my intestinal wall was weakened, food
particles were able to enter my blood stream which then triggered the join
inflammation.
Does anyone have any similar experiences or comments?
ShenMei9 - 19 Oct 2004 07:25 GMT
Makes sense to me, John. Intestinal permeability is sure a key to the degree
of inflammation I have. When I do a vegetable juice fast, I basically have no
arthritic symptoms. There are a lot of people who share your experience.
melinda
Nann Bell - 19 Oct 2004 14:20 GMT
> My hypothesis is that I have a food allergy which promotes my immune system
> to attack my intestine. After my intestinal wall was weakened, food
> particles were able to enter my blood stream which then triggered the join
> inflammation.
>
> Does anyone have any similar experiences or comments?
There are similar stories out there. Such approaches work for some people,
though unfortunately not for all of us. I've tried a couple of the diet
things with no success (never cut out gluten, but the nightshades are NOT the
culprit for me, Pritikin did me no good, eat little red meat anyway, don't
have much diary anyway due to a known milk allergy.......) The really good
news is that you seem to have found food triggers for your disease and you've
learned to avoid them. I hope this continues to work for you!

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Kitty Kelly - 20 Oct 2004 01:18 GMT
I've tried everything you suggested and none of it worked for me.
The problem with your hypothesis, is you don't mention testing it. The
Enbrel alone could have been the reason.
To verify the diet angle you need to try it three times according to my
RD.
-g-
Kitty
John Williams - 20 Oct 2004 03:46 GMT
> The problem with your hypothesis, is you don't mention testing it. The
> Enbrel alone could have been the reason.
That's absolutely correct. That's why I was careful to call it a hypothesis
and not a theory.
The reactions to food happen so rapidly with me (24 hours) that I was able
to find my triggers through trial and error fairly easily.
My feeling with the Enbrel is that I was on it for a year and it helped
immensely, but I would start getting achy again 5-6 days after my last dose.
The Enbrel helped clear my psoriasis only around 30%.
After discovering my food triggers, my psoriasis cleared almost completely.
I had a large, stubborn patch of psoriasis on my lower leg that I have been
trying to get rid of for 5 years now. None of the medications that I tried
cleared it up (Enbrel, methotrexate, prednisone, coal tar wraps, sun
tanning, vitamins in various forms, topical steroids) . Going on this diet
cleared it up in about a month.
I now use Enbrel only about twice a month instead of twice a week
It may well be coincidence but I personally don't think so. I will be the
first to admit that I am probably in the minority who will find relief this
way - perhaps psoriatic arthritis suffers are more likely to have food
allergies.
Hopefully someone will find my post in the usenet archives someday and find
this information useful. If it wasn't for the information in these groups,
I would have never known to look at my diet in the first place.
Harvey R. Stone - 20 Oct 2004 13:17 GMT
>> The problem with your hypothesis, is you don't mention testing it. The
>> Enbrel alone could have been the reason.
[quoted text clipped - 35 lines]
> groups,
> I would have never known to look at my diet in the first place.
Thank you for discussing what has worked for you. Twice a month DMARD with
Enbrel is wonderful.
I hope it continues for you this way.
Harv