Rheumatoid or otherwise?
If rheumatoid, I suggest reading about Low Dose Naltrexone.
If for nothing else than your awaeness.
http://www.lowdosenaltrexone.org/ldn_and_ai.htm
http://www.webspawner.com/users/ldnforra/index.html

Yeah, Jo,

     Have a cotton ball ready to sop up any leakage; I often spring a leak.
And most importantly don't overdo it tomorrow because your energy is
high...you'll pay in pain on Tuesday. Spread the energy out. And see about
spreading out the MTX too....I don't ever take it together with my Enbrel.
Good luck and I'm happy you've got Enbrel.

Hugs from Rosie

Hey Jo,

Are you taking the premix 50MG?  Make sure you warm it up and make
sure the alchol from the prep pad has dried (will definiely help make
it less painful) That said, there are a number of great little videos
on youtube that will show exactly what you need to do and what the
process will feel like. It is somewhat desensitizing to watch other
people do their injections.  One of the problems lots of first timers
have in rushing their injections.  Make sure you take it really slow.
If you are doing the 25 mg, email me.  The issue with the "mix your
own" is making sure you get it mixed will without damaging the
proteins.  I have lots of tips on that process.

m

Hope it went well, Jo. And that it helps you as much as it helps others of
us.

I don't take my mtx and enbrel on the same day, either. Though frankly - I
don't get any energy from the mtx. I do find that the enbrel works better
while I am on mtx than when I'm not.

I get significant 'burn' from the preservative, so I look for areas with
more fat to inject into - like saddlebag area instead of top of thigh. I
also let it warm for 25 minutes. means I only have 5 to complete the shot.
But after a year of using it, the shot is not a big production anymore. And
to remember where to inject, I keep a pattern and repeat the four areas with
each box (R tummy, R thigh, L tummy, L thigh).

Adelle

IIRC, I was letting it warm up more like 30 minutes.  Of course, the room
temp around here is usually cooler than it is for you!  lol  I accidently hit
the reset button on my timer once w/o realizing it and let it warm up for
longer.  Aparently it wasn't long enough to render it ineffective and I found
it didn't sting at all that time.  So letting it warm up as long as you
reasonably can seems to help with the stinging.  

Don't get too wound up about doing it - it really is much easier than I
thought it would be.  My type 1 diabetic brother says the new silicone coated
needles make injections much easier than the old needles.

And assuming you are using the premixed stuff, it will most likely sting at
times.  Just pause the injection until the stinging eases and continue
slowly.  And take Rosie's advice not to overdo it when you get a high from
the Enbrel kicking in!

---
Nann
remove the Gator cheer to email me
       Change everything. Love & forgive.

Well, that's over and done.  Didn't have any rush of energy on
Monday.  Of course that may be because I was due for my MTX Sunday
as well and didn't want to skip it.  Injected several hours after
the Enbrel and in a different location.

This morning I was awake early.  As in the cat told me to lay still
and go back to sleep.  She will barely let me touch her, but sleeps
tight against my legs at night.

I got up a little before six, not unusual as the pain and stiffness
usually drives me out of bed by then.  Fed the dog, and considered
pruning the roses that have needed it for weeks.  Thought, no, I'm
not supposed to over do it, buy hey!.  I don't feel too bad.  Went
out for breakfast for the first time in months and read the paper
and did the Sudoku.  Brought breakfast back for grandson, bacon for
the dog and coffee for Charlie.  (This could start to get expensive)

Its trash day, and the garbage and recycle cans have already been
empties, but the compost can is still half full and waiting for the
truck, so I go ahead and do the roses.

Now it 7:30 and I think at this rate I could get into trouble, so I
came in and sat down at the computer.

But you know, I need to pick up some medicine on base, and could
really stand to stop by the commissary.

Jo