Everyone reacts differently but I use oxycodone/acetaminophen with no
noticable side effects. Different strengths are available so dosage could be
adjusted as necessary. (Percocet/Tylox/generic)

Bud

celebrex

There are three classes of meds used to treat OA.  Only one class, the
Glucosamine and Chondroitin supplements, actually treats the OA.  The others
treat the symptoms of OA, pain and inflammation.

NSAIDs like Celebrex treat the inflammation and also reduce pain to varying
degrees.  All NSAIDs can affect cardiovascular risk, but Celebrex is one of
the safest.  Talk to your cardiologist about your personal situation.
NSAIDs should only be taken if chronic inflammation is a part of your
condition.

Opiod pain medications, like Lortabs and Vicodin, are used just to treat the
pain.  Everyone responds differently to these drugs, so you may have to try
different variations.  A general rule of thumb is that if the drug is making
you high or sleepy, it is either the wrong drug or the wrong dose for you.

Finally, if pain is all you are trying to treat, there are many other
strategies that should be employed, including surgery, physical therapy and
relaxation training.  Antidepressant medications, such as Cymbalta, are also
effective at treating chronic pain.

Hope that helps.

Walt