Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / Diseases and Disorders / Arthritis / January 2008

Tip: Looking for answers? Try searching our database.

heredity

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
Pope Pie (Sy Lehrman) - 19 Jan 2008 04:50 GMT
I have another grandson.  This one is to be named Saffron.  Well, at least
it wasn't Moonbeam.

Anyway, this brings up a question that I know I looked up long ago but I
don't recall.  What exactly is the inheritance potential in the first and or
second generation for RA if both my daughter's parents have it to some
extent?
DeeTee and Bob Taggart - 19 Jan 2008 05:23 GMT
Don't know the answer, but wanted to say congrats!!

DeeTee

>I have another grandson.  This one is to be named Saffron.  Well, at least
>it wasn't Moonbeam.
[quoted text clipped - 3 lines]
> or second generation for RA if both my daughter's parents have it to some
> extent?
Kelly C. - 19 Jan 2008 05:50 GMT
The way my RD explained it to me, you could carry the marker all your life,
and never develop the illness. It's a total crapshoot.

Neither my mother nor Father have RA, but my father's father had an
aggressive case, like I do. None on my mother's side.

My father has 7 siblings. One of them has RA. The rest have a variety of
other arthritic conditions.

Sorry if this doesn't help much.:)

Kelly C.

>I have another grandson.  This one is to be named Saffron.  Well, at least
>it wasn't Moonbeam.
[quoted text clipped - 3 lines]
> or second generation for RA if both my daughter's parents have it to some
> extent?
Diane - 19 Jan 2008 19:59 GMT
Saffron. What a beautiful name. Reminds me of Johnie's grandson,
Acacia. Congratulations!

As for heredity. My family participated in a study (probably still
going on) through the Long Island Jewish Hospital (I may have that
name slightly wrong). The theory behind the study is that autoimmune
diseases run in families and may be expressed in different ways. For
example, there are 4 siblings in my family. My sister has MS, i have
RA, my brothers were supposedly  "normal." (ha!) so we all had to send
in blood samples and our medical histories were taken at length over
the phone. turns out my younger brother has psoriasis, which i never
knew about, and my older brother's long time kindey disease is also
considered autoimmune. so we ALL have some form of an autoimmune
disease, which was passed down (most likely) on our mother's side. Our
mother had polymyalgia rheumatica. Her mother, my grandmother, had
something crippling--probably RA. The upshot of all this is that,
theoretically speaking, the gene for autoimmune diseases runs in
families, but something triggers its expression (they don't know what
yet) and it may show up as a different disease in different
individuals.
and since this is all theoretical, it might all be disproven. but my
family is quite the autoimmune trainwreck. (might be genes or might be
from growing up in new jersey. . . )

the GOOD news is, that if little saffron develops anything at all,
research into these diseases is happening at such a rapid rate that
chances are he can be cured or the disease halted before any damage
occurs. i wish him a long a very healthy life.

diane
Carole - 19 Jan 2008 20:54 GMT
the Long Island Jewish Hospital (I may have that
> name slightly wrong).

Nope, that's the correct name. I used to live near there :)

Carole
Pope Pie (Sy Lehrman) - 21 Jan 2008 03:28 GMT
> Saffron. What a beautiful name. Reminds me of Johnie's grandson,
> Acacia. Congratulations!
[quoted text clipped - 5 lines]
> example, there are 4 siblings in my family. My sister has MS, i have
> RA,

Now there is a depressingly familiar state of affairs.  My sister has MS and
it is progressing ominously, getting into her brain.  I spent the summer
nursing her through a series of delusional events which she insists were due
to her medications, but still the scans say otherwise.  We shall see.

My daughters mother has apparently a mild case of RA and that is the least
of her problems.  The daughter has had her spine partly rebuilt from
plastic.

I think we are all a mess.
Leslie & The Furbabies in MO. - 21 Jan 2008 03:42 GMT
No RA anywhere in my family- lots of OA.  I got both- severe OA and mild RA.
Myself and both my brothers have fibro- rather unusual in men and two male
siblings???

Leslie

>> Saffron. What a beautiful name. Reminds me of Johnie's grandson,
>> Acacia. Congratulations!
[quoted text clipped - 17 lines]
>
> I think we are all a mess.
Nann Bell - 21 Jan 2008 13:34 GMT
I'm another of those with auto-immune crud on both sides of the family, going
back at least two generations before me.    My brother and I each got at
least one major autoimmune illness.  Our sister only had allergies until
about age 50 when her thyroid started dropping out.  Don't konw for sure if
it's Hashimoto's, but that is the most likely cause.  Thus far though it's
all stuff like that and RA, PsA, PMR,  type 1 diabetes, fibro and masses of
allergies all around.  Nothing as miserable as MS, thank goodness.

I talk about our family's genetic cesspool.....

Signature

Nann
remove the Gator cheer to email me
Simply the thing I am shall make me live --- William Shakespeare
On Sun, 20 Jan 2008 22:28:04 -0500, Pope Pie \(Sy Lehrman\) wrote
(in message <mjUkj.20190$E01.3306@newsfe22.lga>):

>> Saffron. What a beautiful name. Reminds me of Johnie's grandson,
>> Acacia. Congratulations!
[quoted text clipped - 16 lines]
>
> I think we are all a mess.
sweetpickleNO@SPAMknology.net - 21 Jan 2008 15:03 GMT
my mother had severe ra and daddy had severe oa.  thankful that i got his
instead of hers.  oa is bad enough!
gwen

> I'm another of those with auto-immune crud on both sides of the family,
> going
[quoted text clipped - 32 lines]
>>
>> I think we are all a mess.
jofirey - 19 Jan 2008 20:56 GMT
>I have another grandson.  This one is to be named Saffron.  Well, at least
>it wasn't Moonbeam.
[quoted text clipped - 3 lines]
> or second generation for RA if both my daughter's parents have it to some
> extent?

Welcome to the world, Saffron.

(This boy needs a nickname - soon)

To the best of my knowledge, every descendent of my paternal great
grandparents has autoimmune problems of some sort.

They have also all, for the most part lived long, happy, useful and
productive lives.

I'm posting some pictures later this weekend.  I'll include a before and
after picture of my paternal great grandmother.  She was in a lot of pain in
her later years.  Her grandchildren thought she was just bad tempered, but
grew up to understand more than they wanted to.  Her great grandchildren are
grateful for medical advances.

Jo
ANN M - 21 Jan 2008 04:19 GMT
One of my mother's sisters had severe RA and was non-ambulatory for
several years prior to passing away in her 60's. Several other members
of the family had either RA or OA.  I am the only child on that side of
the family and have RA.  I do believe heredity plays a part in
auto-immune diseases.
Ann
Squirrely - 22 Jan 2008 05:52 GMT
The twins have JRA and I have OA, my fathers family all of them have RA.

I do have Hashimotos, Asthma, and Addisons which I have read are autoimmune.
So that is maybe my autoimmune part of this.

Signature

Love and Hugs to all
Jo the squirrely one
I am nuts about you.

> One of my mother's sisters had severe RA and was non-ambulatory for
> several years prior to passing away in her 60's. Several other members
> of the family had either RA or OA.  I am the only child on that side of
> the family and have RA.  I do believe heredity plays a part in
> auto-immune diseases.
> Ann
Nell - 22 Jan 2008 21:10 GMT
> The twins have JRA and I have OA, my fathers family all of them have RA.
>
[quoted text clipped - 7 lines]
>> auto-immune diseases.
>> Ann

I have twin daughters and one has JRA (they're fraternal) and both have
asthma. One of my mother's sisters had psoriatric arthritis, adult onset
asthma, hypothyroidism (don't know what kind), and OA. Her other sister had
OA. Her brother (still living) has mild psoriasis. My mother had asthma and
hypothyroidism. My grandfather had eczema.

My dad's sister had severe RA, very crippled up by her 40s. Died of a wasp
sting at age 61.

I have asthma, OA, psoriasis (not severe, though), asthma, fibromyalgia,
scleroderma with features of lupus, MCTD (or UCTD--I always mix them up),
and hypothyroidism.

Yippee-doodle.

Nell
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2008 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.