I have this problem alot.  I've taken quinine for ten years and it
helps!  Especially at night!  But the FDA will no longer allow it to
be prescribed for this problem.  (I still have a few left.)  I've
tried Klonapin but my insurance gives me fits every time I try to take
it.  (which I have done twice.)  But restless leg syndrome needs to be
properly diagnosed by your doctor.  There are some serious reasons for
it such as diabetes, nerve problems, foot problems etc.  Only your
doctor can come up with a correct prescription.  But some things to
try in the meantime are:  change positions-sit, stand, another chair,
lay, etc, have someone massage your legs, try heat/cold, even change
clothes-the seams will bother me sometimes, use pressure on the ball
of your foot.  But the most important is to talk with your doctor!

Take care,

Vickie B.