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Medical Forum / Diseases and Disorders / Arthritis / December 2006

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Metho or sulfasalazine

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estherg - 07 Dec 2006 15:07 GMT
I was recently diagnosed with inflammatory arthritis (either RA or Psoriatic
it's not clear which) and the doctor started me on a 6 pack of prednisone.
When that is finished he would like to start me on metho 3 pills once a week.
He was considering sulfasalazine but felt the metho would work faster.  I
have read alot about metho's side effects but not much about sulfa.  Can
anybody give me some info on it?  A bit about myself, I am 29 and aside from
the occasional stiffness in my knees due to inflammatory fluid and a couple
of achy joints I am functioning ok.  I am not in excruciating pain but I am
uncomfortable and the prescription anti-inflammatories do not seem to really
help.  Being that I am not feeling that badly, does it make sense to even
start either of these drugs?  If I understand correctly these are long term
medications.  I would appreciate any input, Thanks
                         Esther
Kelly - 07 Dec 2006 21:09 GMT
mtx (methrotrexate) is the gold standard for inflammatory arthritis and is
probably the most studied and known about med we have in our arsenal.  It is
commonly combined with other meds such as sulfasalazine to provide the
needed oomph to make them work or to stop damage from the joints or to allow
the other meds to work without developing antibodies to them.  Most good
rheumatologists now start on the dmards of which mtx is the basic.  The old
way used to be to start people on the anti-inflammatories and not go into
the dmards until pain got bad.  By that time organ involvement and joint
damage had occured and it was too late to reverse.  Your doctor has
prescribed the prednisone as a stop gap just to help you over the hump until
the dmards have started working.  The mtx does defininitely work faster on
most people - plaquenil and sulfasalazine are usually milder meds.  You want
to get this before it gets uncomfortable - before you are feeling bad -
especially at 29 and especially due to the fact you have occasional
stiffness, uncomfortable etc.  Psoriatic arthritis in particular can be hard
to get control of.

It sounds like you have a good doctor - is he a rheumatologist - if not you
should have a rheumatologist taking care of helping your doctor and you (RD
in case you are wondering initials we describe here.

Any questions ask away.  We have a great supportive group and information to
help you through the many questions you probably have.  Welcome - although
we would rather you were not here with inflammatory arthritis.

Kelly

>I was recently diagnosed with inflammatory arthritis (either RA or
>Psoriatic
[quoted text clipped - 16 lines]
> medications.  I would appreciate any input, Thanks
>                          Esther
estherg - 08 Dec 2006 18:13 GMT
Why is prednisone so bad for the body long term?
Esther

>mtx (methrotrexate) is the gold standard for inflammatory arthritis and is
>probably the most studied and known about med we have in our arsenal.  It is
[quoted text clipped - 28 lines]
>> medications.  I would appreciate any input, Thanks
>>                          Esther
Harvey R. Stone - 08 Dec 2006 22:58 GMT
> Why is prednisone so bad for the body long term?
> Esther

Hi Esther,    Our body makes its own kind of prednisone each day to help the
body handle the stresses of another day.   Sometimes we do not make enough
to meet the requirements and extra helps.  I am not against prednisone but a
person must realize the side effects of taking it and long term it does
think a person bones just like it thins our skin and myself,,,,, I also have
pimples to go along with it.    I do not take prednisone everyday and will
not if I can help it.   For one thing, the body stops making its own if you
take 15 mg or more a day.
  Why is it bad of the body long term??? It depends on how its taken and
for how long.   It is something a person and their doctor need to work out
for the best results.  Many people take bone X rays each year to check to
see if damage is being done.

Harv
RoseB - 10 Dec 2006 02:53 GMT
>Why is prednisone so bad for the body long term?
>Esther

Prednisone use over time causes premature aging. Research indicates
that it can lead to osteoporosis, cattaracts, thinning of the skin,
increased bruising and other unwanted side effects.
    Rose   @}>->--
    Being educated means that rather than fearing the unknown, one seeks to understand it. RB

    Please remove "Ima" to reply.
 
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