I have been on it since about 1993. I am on 1cc or 25 mgs by
injection. At first I experienced some fatigue, but that has not been
an issue for a few years now. Other than that I have had to side
effects and my LFTs have almost all ben in the normal range.

    Rose   @}>->--
    Being educated means that rather than fearing the unknown, one seeks to understand it. RB

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I have been on it for over 2 years, the only side effect I have is sometimes
fatigue but not always, at first it bothered me a lot more than it does now.
I take 20 mg a week
Becky

I took it for 5 years - went off it because my labs showed a seriously
disturbing drop in the protein produced by the liver.  All other testing,
including a biopsy, showed my liver to be fine though.  Both docs are
watching things and my RD IS considering putting me back on it if my
condition so warrants (and it seems to be the past few weeks).

My dad was one of the first people to take mtx for RA.  He was on it for
about 23 years with no complications - at 15-20 mg per week.  He only stopped
because a heart attack killed him when he was 82.

Hello,
I have been on MTX for about 15 years.  I take 20mg per week (now down
from 30).  At first I would get nauseous, so I had to take folate to
stop that.  Now I don't seem to have any side effects.  The liver is
managing.  My hair did become a little thin, but then cyclosporin was
added to my medication and then I got more hair then I wanted.  Don't
forget to have your blood tested regularly just in case.
Gail

I have been on it for 23 years, with a stop of 2 years when i changed docs.
most of the time i took 7 1/2 mgs by injection.  now on 15 mgs.  no side
effects.  shirlawn