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Medical Forum / Diseases and Disorders / Arthritis / August 2006

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Drug Combo - bone density

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Califchief - 28 Aug 2006 14:28 GMT
SAN JOSE - August 12, 2006

Forgot milk?  Better get to know Forteo and Fosamax. In
a study with potentially life-altering implications for
millions of Americans with osteoporosis, researchers at
the University of California - San Francisco have found
that new bone can be formed -- and then maintained --
by taking a hormone for one year and a popular Rx drug
for the next year.
The findings, which appeared in yesterday's New England
Journal of Medicine, raise hopes that stronger bones
might mean fewer broken hips and so-called dowager's
humps, boosting quality of life for many seniors and
saving billions annually.
Scientists cautioned that the new study does not track
whether the drugs result in fewer fractures.  Instead,
it measured bone density in patients taking the drugs
in combination or alone.
The results were positive enough for researchers to
say physicians should be discussing the therapies with
their patients, and patients should consider taking
them.
Researchers studied 238 women.  Those who took the
experimental hormone similar to the FDA-approved
Forteo, which builds bone, and followed it with a year
of Fosamax, which prevents bone-density loss, saw the
bone density in their spines increase an average 12%.
But the researchers were suprised by another finding.
Not using Fosamax during the 2nd year erases almost
all the gains.
The findings are important because patients were not
supposed to take Forteo, which can cost $6,000+ a year
for more than 2 years because of concerns that long-
term use could be cancerous.  Doctors have been
grappling with how to treat osteoporosis once patients
stop taking forteo.

... Dolly Parton to Mrs Folger: Yes, they are Mountain Grown!
d'huit - 30 Aug 2006 03:47 GMT
interesting, chief.  they've got me on 50,000 units of vitamin D for mine.
don't know why none of my docs will put me on evista, fosamax or whatever.

kate
SAN JOSE - August 12, 2006

Forgot milk?  Better get to know Forteo and Fosamax. In
a study with potentially life-altering implications for
millions of Americans with osteoporosis, researchers at
the University of California - San Francisco have found
that new bone can be formed -- and then maintained --
by taking a hormone for one year and a popular Rx drug
for the next year.
The findings, which appeared in yesterday's New England
Journal of Medicine, raise hopes that stronger bones
might mean fewer broken hips and so-called dowager's
humps, boosting quality of life for many seniors and
saving billions annually.
Scientists cautioned that the new study does not track
whether the drugs result in fewer fractures.  Instead,
it measured bone density in patients taking the drugs
in combination or alone.
The results were positive enough for researchers to
say physicians should be discussing the therapies with
their patients, and patients should consider taking
them.
Researchers studied 238 women.  Those who took the
experimental hormone similar to the FDA-approved
Forteo, which builds bone, and followed it with a year
of Fosamax, which prevents bone-density loss, saw the
bone density in their spines increase an average 12%.
But the researchers were suprised by another finding.
Not using Fosamax during the 2nd year erases almost
all the gains.
The findings are important because patients were not
supposed to take Forteo, which can cost $6,000+ a year
for more than 2 years because of concerns that long-
term use could be cancerous.  Doctors have been
grappling with how to treat osteoporosis once patients
stop taking forteo.

... Dolly Parton to Mrs Folger: Yes, they are Mountain Grown!
Fire Chief - 30 Aug 2006 07:10 GMT
Kate wrote:

> interesting, chief.  they've got me on 50,000 units of vitamin D for mine.
> don't know why none of my docs will put me on evista, fosamax or whatever.

My rheumy gave me a 3-month supply of Fosamax to try before
he writes me a 'script for it.  This is in a major arthritis center
which conducts dozens of on-going clinical trials during the
5 years I've been a patient.  He arranged my THR within 3-5
months after my 1st visit, after the bitch I'd been seeing for 8
years said, "Welllllllllllllllll, it may be too late."   This after
she kept
stating, "Wait 'til you can't stand it (pain) any more."  I don't know
how the whore retains her medical license and board certification
from the American College of Rheumatology.

... 9 in 10 doctors believe Epoxy can be cured.
 
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