Rusty the 'Tard appears to suffer not only from OCD's but
schizophrenia,
megalomania and masochism, coupled with low self-esteem and a hignly
confused sexuality.
No wonder he's unable to function in society and lives on the public
dole

Obsessions are repeated, persistent and unwanted ideas, thoughts,
images or impulses that you have involuntarily and that seem to make
no sense. These obsessions typically intrude when you're trying to
think of or do other things.

Compulsions are repetitive behaviors that you feel driven to perform.
These repetitive behaviors are meant to prevent or reduce anxiety or
distress related to your obsessions. You may also make up rules or
rituals to follow that help control the anxiety you feel when having
obsessive thoughts.

Nope, the nobel would not be given for such a minor observation, however
important for a direction for future research.  They found a malfunction
in the brain as the cause, not what is in the diet.

Still ordering the travel brochures about oslo are ya?  Here is the
important finding:

"His study in the July edition of the Journal of Alzheimer's Disease
supports the idea that toxic levels of amyloid beta protein, the
substance scientists believe is responsible for Alzheimer's disease,
accumulate in the brain because a pump that pushes it into the blood
and past the blood-brain barrier malfunctions."

"the sound of how awesome I am."

Yup, absolute silence.  Or, do we hear a drip?

Nobel prize - - yup, a drip do we hear.

Nobel Prize And Alzheimer's  

Group: alt.support.alzheimers Date: Thu, Jul 9, 2009, 8:15am From:
ironjustice@rock.com (ironjustice)
Here's the Nobel .. again ..
Inflammation may trigger Alzheimer's disease, Saint Louis University
findings suggest
Published: Wednesday, July 8, 2009 - 15:45 in Health & Medicine
The anti-inflammatory drug indomethacin could hold promise as a
treatment for Alzheimer's disease, says a Saint Louis University doctor
and researcher. Two research studies published by William A. Banks,
M.D., professor of geriatrics and pharmacological and physiological
science at Saint Louis University School of Medicine, support this
conclusion and offer what he calls a "one-two punch" in giving clues on
how Alzheimer's disease develops and could be treated.
His study in the July edition of the Journal of Alzheimer's Disease
supports the idea that toxic levels of amyloid beta protein, the
substance scientists believe is responsible for Alzheimer's disease,
accumulate in the brain because a pump that pushes it into the blood and
past the blood-brain barrier malfunctions.
The blood-brain barrier is a system of cells that regulates the exchange
of substances between the brain and the blood. The blood- brain barrier
transporter known as LRP is the pump that removes amyloid beta protein
from the brain and into the bloodstream.
"LRP malfunctions like a stop light stuck on red, and keeps amyloid beta
protein trapped in the brain," said Banks, who also is a staff physician
at Veterans Affairs Medical Center in St. Louis.
He tested the hypothesis by giving mice an antisense, which is a
molecular compound that blocked the production of LRP. Amyloid beta
protein accumulated in the brain and the mice showed memory loss and
learning impairment.
The finding raises the question of what causes LRP to malfunction.
Banks' study in the May issue of Brain Behavior and Immunity suggests
inflammation as the culprit and supports using indomethacin, an anti-
inflammatory medication, as a buffer to protect LRP from being turned
off.
Inflammation, which is part of the body's natural immune response,
occurs when the body activates white blood cells and produces chemicals
to fight infection and invading foreign substances.
"We induced inflammation in mice and found that it turned off the LRP
pump that lets amyloid beta protein exit the brain into the bloodstream.
It also revved up an entrance pump that transports amyloid beta into the
brain. Both of these actions would increase the amount of amyloid beta
protein in the brain."
Banks then gave mice indomethacin, which prevented inflammation from
turning off the LRP (exit pump).
His findings help to explain what doctors who are studying the use of
indomethacin to treat people with Alzheimer's disease are seeing in
their clinical practice.
"Nonsteroidal anti-inflammatory drugs, especially indomethacin, have
been associated with protection against Alzheimer's disease. Our work
could influence that debate and thinking at the patient-care level,"
Banks said.
Source: Saint Louis University
----------------
Sir James Black, who received the Nobel Prize for his invention and
development of Tagamet (Cimetidine), the pioneer drug for treating GERD
and ulcerations.
http://tinyurl.com/33vvo
------------------------------
http://www.ncbi.nlm.nih.gov/pubmed/12603077
The results imply that indomethacin provides a neuroprotective effect by
binding to iron and thus making it unavailable for free radical
production.
PMID: 12603077, UI: 22490682
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
=========================
Good information, Ironjustice, but what took them soooooooo long to
discover that a pump is in the brain, LRP, that removes amyloid beta
protein from the brain and into the bloodstream??? I wonder how long it
takes them to determine inflammation doesn't happen out of the blue but
something causes it like a virus?  Gee whiz, I wonder what they could
accomplish if they weren't spending so much time eating doughnuts and
drinking coffee all day?