On Aug 13, 4:57 pm, "ironjust...@aol.com" <ironjust...@aol.com> wrote:

Please, pay attention, this is quite new, the paper published at the J
Neurol (Barcelona) at the beginning of 2007

THE  ALTERNATIVE THEORY FOR THE ALZHEIMER PROCESS

DIFFUSION TEXT
ALZHEIMER PROJECT ARGENTINE, AUGUST 2007

The Chronic Progressive Dementization, (CPD), the scientific name of
that vulgarly called alzheimer, is a quite different question than
depression, different types of psychosis and obviously of sometimes
surprising behaviors of the normal aging, and in the long run much
more serious.

Although the final phase of cerebral disintegration is similar, there
are two types of processes: the one that occurs in young adults or
greater adults, and another different one that it happens in very
greater adults, around 80 years or more. In these, at the final phase
the problem it is “simply” the loss of the vital motivation, the
exhaustion of desire to continue living. Abandonment of dreams, as
Miguel de Unamuno would say on the cession of such dreams that Don
Quixote in favor of Sancho did, and then, obviously, dying.

Persons with risk for a CPD (alzheimer) are those that generally have
an introverted personality, few and restricted social relations, with
and isolation tendency, coping deficit for difficulties and losses,
tendency to depend on others, to had constructed their personal
identity in the shade of another one (the woman of the doctor, the
husband of…) or some other equivalent transference, tendency to be
obstinate to proper painful events or of the other’s life, which is
diagnosed in general like depression.

THEN, IN ANY WAY IT TOUCHES TO ANYONE.

There is nothing of chance’s dependence, neither suddenly nor no
magician in it. Logically with advance into years the probability that
these people suffer a painful loss increases, obviously, like
everybody. With its coping deficit the risk increases enormously when
they have a painful loss, for example her husband who gave or lent the
personal identity, or a son or daughter who gave sense to their life,
of their work that justified the existence to him, of their corporal
and mental capacity to which he had bet or concentrated, and when not
counting on a familiar network and a social network that stopped its
fall after the duel impossible to elaborate and to go on, the person
collapses.

It is the beginning of the aim. It can have 40 years old (the younger
case than we have was a woman of 38 years), or 80 yo. It does not
related to aging, but only that when they advance the years is more
probable that we suffer painful losses. Until this moment its brain is
totally normal, does not show absolutely anything abnormal and is
totally useless to want to see something in images or less even in
electroencephalograms, that it is something so coarse and inadequate
as a toad arrives of a luxurious piano of tail.

The landslide of the person, its “delivery” as much in the dictionary
of the Real Spanish Academy like in the original dictionaries of all
the languages, is expressed in the idea to wish to die, in the
fixation of the attention in its own one and wished death. Then the
abnormal thing begins, the unnatural thing, the destructive thing,
because in fact we are programmed biologically, ancestrally, for all
the opposite, as it is to explore, to fight, to defend to us, to hunt
(in the literal sense and the symbolic sense), to attack, to ask to
us, to inquire to us, and our attention concentrated in each objective
part of a basic alert status that we never lose, except for when we
slept very well. We are not programmed to give to us tamely, as it is
not it in any animal.

How takes place then the cerebral damage that leads to the death?

To understand this we need to explain some very basic things, although
surprising little known. In the first place that we have nine senses:
vision, hearing, equilibrium, tact, space perception/orientation,
taste, sense of smell, sense of strange it (or familiarity sense) and
of the corporal perception. All these senses, and perhaps others more,
are active in the basic alert status and they have two components: an
automatic one of immediate reaction (one falls in love a light and
blinking, it smells sulphydric vapors, the substance that is put to
the gas tubes to detect a loss immediately, and I separate, etc.), and
another component of recognition, in which the stimuli are sent to the
brain and there it is collated if that information has been loaded.
They are the sensorial recognition systems we have.

Then, EVERYTHING WHAT WE DO, EVERYTHING WHAT WE THOUGHT, BY MORE BANAL
OR INSIGNIFICANT THAN IS, IS RECORDED IN THE BRAIN IN FORM OF NEURONAL
NETWORK IN WHICH  PARTICIPATE  NEURONS OF THIS SENSORIAL RECOGNITION
´S  SYSTEMS OF THE NINE CHANNELS, INEXORABLY.

And those networks that are armed in our brain also were reinforced
when we return to make the same act or the same thought.
But in addition BECAUSE IN FACT ALL IS CONCECTED WITH ALL, WHICH WE
ARE GOING TO DO WAS CONNECTED IN MORE OR LESS STRAIGHT FORWARD FORM
WITH WHICH ALREADY WE HAVE DONE AND LOADED LIKE NEURONAL NETWORKS IN
OUR BRAIN.

Some of those connections have a great importance in the every day
actions and others very remotely: although the door seems to be very
heavy, already we know that the force that we must make to open it
isn’t so high. Or for example the natural attraction by rhythm that
are multiple or sub multiple of the heart rate (that we listened for
the first time in our mother’s uterus), seems like related with this
indeed. That is to say, to live means to be stimulating everything
somehow what we have done, lived and thought. It seems exhausting, but
it is a fascinating question.

However, when a person fix attention to death, that is something
abstract that does not required any motor or cognitive reply, AND
RESORTING TO THE NATURAL AND AVAILABLE MECHANISM DISPOSED IN ALL
PERSONS THEY TO BLOCK THE RECEPTION OF OTHER STIMULI WHEN WE
CONCENTRATED THE ATTENTION IN SOMETHING INTENSIVELY ATTRRACTED, THESE
PEOPLE HAPPEN TO BLOCK, at the outset in oscillating form, with
variations throughout a day or of days, THE SENSORIAL STIMULI OF THE
DIFFERENT CHANNELS. It is a biological basic mechanism since we must
be concentrated in the tiger that attacks to us and we cannot disperse
with the colored birds that are jumping back: it’s a survival
principle. Who know more the utility of this principle are the
pickpockets of the human agglomerates: one of them produces a smaller
but clear aggression on the victim. In reaction the victim is put in
guard and concentrates its attention on the aggressor, while his
companion removes the wallet or cuts the portfolio’s strap, because we
have blocked the tact and the corporal perception when putting to us
in guard in front of the aggressor and concentrating the attention in
him.

The displacement of the attention towards different objectives is a
normal and a routinely task, but in the people who enter CPD process
they are persistently blocking the reception of stimuli by the
different sensorial channels and the consequent arrived to the brain,
so that the neurons of the sensorial recognition systems that comprise
of the sensorial networks doesn’t receive stimuli, with which in the
long run lose the synaptic connections and the networks are disarmed.
Something equivalent to the atrophy of a muscle we never use. This
avoid progressively all the recognition tasks. No longer they
recognize, no longer have capacity of recovery of recent events (weak
neuronal networks, with low sensorial stimulation), and however still
can recover events of the past. But not anyone, but THOSE IN WHICH THE
LIVED EVENTS (SENSORIAL NETWORKS ARMED IN THE PAST) WERE POSSIBLE WITH
A GREAT STIMULATION (EMOTIONAL), PROLONGED REINFORCED AND CONNECTED
WITH MULTIPLE OTHER SENSORIAL NETWORKS, LIKE THE DOOR OF OUR HOME AT
OUR CHILDHOOD, by where we did not shelter, by where we shook to
arrive all smeared, by where we arrived to eat, etc.

Thus, those faults of the systems of sensorial recognition were the
more consistent biological indicators to detect that a person is in a
dementia of this type.

THE PROGRESSIVE DISINTEGRATION OF THE NEURONAL NETWORKS IN OUR BRAIN
BY STIMULATION DEFICIT OF THE RECOGNITION SENSORIAL SYSTEMS IS THE
ESSENCE OF THE DEMENTIZATION PROCESS, AND LEADS TO THE DEATH BECAUSE
AN AUTOMATIC ESSENTIAL SYSTEM HAS CONNECTIONS WITH SENSORIAL NETWORKS
YOU, THAT WHEN ALSO THEY GET TO BE AFFECTED, CAUSES THE DEATH.

Then isn’t properly a disease (“signs and symptoms that responds to a
well-known cause”), isn’t genetic, it doesn’t have relation with aging
(confusion comes from that to greater age is the probability of
suffering painful losses, that are a very frequent trigger one, since
we have already said), does not begin with any damage in the brain but
that concludes in the long run in this, isn’t a problem of the memory
but of the attention, and before this one of the desire, and before
this one of the satisfaction search, and before this one of the
biological and psychological impulsions arranged by the will, and even
before the basal state of alert that characterizes to us. One of the
last forms of the expression of the process is the problem with the
memory, but in fact the difficulty to recover events is the last link
of a very long chain, and to have concentrated in it and not in the
attention’s deficit of can be the reason of the delayed to understand
the process, we think.

And finally, isn’t irreversible, since it is possible and it gives
clear and forceful result, to elevate to those people the self-esteem
and the attention to him, and to permute the abstract idea to him of
death wished by the one of real life that surrounds it, the shade by
the light that surrounds us to all to little that we lend a little
attention, taken care of and love, and inserting it in a new extolling
routine for the dairy life. It is not easy, is an abyss of difference
with giving a tablet, but it is tremendously positive as much for the
affected ones as for which we worked with the protocols derived from
the psycho-social neuro sensorial disintegrative theory of the chronic
progressive dementization.

Prof.Lic.Luis María Sánchez de Machado,
Neurobiologist, Director,
Alzheimer´s  Project Argentina
TE 0054 3442 431442   stopalz@gmail.com    www.stopalz.org