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Medical Forum / Diseases and Disorders / Alzheimer's / June 2007

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Upbeat article in the AARP Bulletin

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Alan Meyer - 09 Jun 2007 01:59 GMT
I know, I know.  We'll believe it when we see it.  But if you
want to read a little positive news, have a look at:

 http://www.aarp.org/bulletin/yourhealth/alzheimer.html

There are nine Alzheimer's drugs in Phase III trials and
"dozens" more in Phase II.  Many of these drugs attempt
to slow, halt, or even reverse the disease, as opposed
to the past crop of drugs that did nothing for the progress
of the disease but attempted to improve functioning in
spite of the disease.

Maybe those of us that don't yet have it can look forward
to a better end of life than our parents had.  Maybe those
of us caring for loved ones want to take another look at
enrolling them in clinical trials.

One of the things we sometimes ask in this group is, why
consider an unproven trial drug, especially when it could
be a placebo, when there are proven drugs available?

But the proven drugs are only proven to alleviate symptoms,
not to halt or even slow the progress of the disease.  And
even then, they don't work for everyone.  So maybe the
clinical trials are worth another look.

   Alan (the perpetual optimist)
Baird Stafford - 09 Jun 2007 09:00 GMT
> I know, I know.  We'll believe it when we see it.  But if you
> want to read a little positive news, have a look at:

>   http://www.aarp.org/bulletin/yourhealth/alzheimer.html

It's a good thing it was the screamer on the front page of their rag.  
I'd have missed it, otherwise. since I never read the thing....

> There are nine Alzheimer's drugs in Phase III trials and
> "dozens" more in Phase II.  Many of these drugs attempt
> to slow, halt, or even reverse the disease, as opposed
> to the past crop of drugs that did nothing for the progress
> of the disease but attempted to improve functioning in
> spite of the disease.

Don't knock it.  They had to start somewhere - and there are more than
like some folks' parents, somewhere out there, who are still functioning
on the slower-downers and will continue to do until the arrestors and/or
regressors are released.

> Maybe those of us that don't yet have it can look forward
> to a better end of life than our parents had.  Maybe those
> of us caring for loved ones want to take another look at
> enrolling them in clinical trials.

I've got my fingers crossed, hard!  I don't want my SO, who is sixteen
years younger than I and my only family nearby, to have to go through
what I'm going through with the Dowager.

<snip>

Baird
Evelyn Ruut - 09 Jun 2007 12:15 GMT
>> I know, I know.  We'll believe it when we see it.  But if you
>> want to read a little positive news, have a look at:
[quoted text clipped - 28 lines]
>
> Baird

Oh Baird, I surely know what you are saying.   But I don't think it is
always hereditary either, though they have identified some genetic component
to it.
Signature

Best Regards,

Evelyn

Alan Meyer - 09 Jun 2007 19:01 GMT
>> ...
>> I've got my fingers crossed, hard!  I don't want my SO, who is sixteen
[quoted text clipped - 3 lines]
> Oh Baird, I surely know what you are saying.   But I don't think it is always hereditary
> either, though they have identified some genetic component to it.

My wife and I are about the same age.  Both of us had parents
that suffered from AD.  So we're both acutely conscious of
the risks and aware of the suffering it inflicts on the entire
family, not just the patient.

It goes without saying that all of us here are intimately
acquainted with this fear.

   Alan
Evelyn Ruut - 09 Jun 2007 19:24 GMT
>>> ...
>>> I've got my fingers crossed, hard!  I don't want my SO, who is sixteen
[quoted text clipped - 14 lines]
>
>    Alan

Yes.  No doubt about it.   One thing I did do was make sure I had all my
paperwork in place in case heaven forbid.......  That's something some
people don't look into until it is very late.

Signature

Best Regards,

Evelyn

Mary_Gordon@tvo.org - 09 Jun 2007 22:31 GMT
I'm not so much worried about heredity as I am that about the sobering
truth that if you are lucky enough to live into your mid 80's your
odds of having cognitive impairment from some cause is 50-50.

Being disabled physically might make life a challenge, but nothing
like being mentally impaired where you really are dependent in every
way, like a toddler.

M
Chuck Whealton - 10 Jun 2007 17:41 GMT
> I know, I know.  We'll believe it when we see it.  But if you
> want to read a little positive news, have a look at:
[quoted text clipped - 23 lines]
>
>     Alan (the perpetual optimist)

'Ya know?  I guess it's somewhat encouraging.  And I have read about
at least one trial (the pharmaceutical escapes me) where the results
in the non-placebo group were so positive that they put the placebo
patients on the real pharmaceutical.

I guess we'll see.  I know I'd never want to put my own family through
it with me.

Charles R. Whealton
Charles Whealton @ pleasedontspam.com
Easter Stephens - 10 Jun 2007 18:44 GMT
I have Diabetes And Alzheimers.....We have found the Diabetes Pills are
helping my Alzheimers....It has been 7 years since I found out I had
it.....But I really believe the Diabetes pills is protecting my brain...
Alan Meyer - 10 Jun 2007 23:28 GMT
>I have Diabetes And Alzheimers.....We have found the Diabetes Pills are
> helping my Alzheimers....It has been 7 years since I found out I had
> it.....But I really believe the Diabetes pills is protecting my brain...

Seven years!

You're doing great Easter.  You're an inspiration to us all.

Keep fighting it.  We're all rooting for you.

Regards,

   Alan
Dennis P. Harris - 11 Jun 2007 06:34 GMT
> I have Diabetes And Alzheimers.....We have found the Diabetes Pills are
> helping my Alzheimers....It has been 7 years since I found out I had
> it.....But I really believe the Diabetes pills is protecting my brain...

easter, i'll say this again.  you need to get another opinion.
your description of rapid onset and then stabilization of the
disease, along with your diabetes and high blood pressure, are
what are normally seen with a VASCULAR DEMENTIA caused by
strokes, blockages, or hemorrhage in the brain, and not with
Alzheimers.  

you really need to ask your doc for a referral for a full exam to
diagnose what you really have so you can get proper treatement
for your brain damage and its cause as well as your diabetes.
Evelyn Ruut - 11 Jun 2007 13:09 GMT
>> I have Diabetes And Alzheimers.....We have found the Diabetes Pills are
>> helping my Alzheimers....It has been 7 years since I found out I had
[quoted text clipped - 10 lines]
> diagnose what you really have so you can get proper treatement
> for your brain damage and its cause as well as your diabetes.

I don't think she reads here much.
I also wonder if anyone is taking care of her.
It's kind of sad that she thinks her diabetes pills affect her mind.

Signature

Best Regards,

Evelyn

 
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