Hi, I've just joined this group. Although my mum hasn't been diagnosed,
she seems to be showing symptoms of mild cognitive impairment for the
last year and I am worried sick that she will go on to devlop
Alzheimers or dementia. I seem to be in tears every day. She is 71 and
takes levothyroxine for an under-active thyroid. She has been taking
Ibuprofen every day for the last week as we heard of studies which
seemed to indicate this could help. I know though that long-term use of
Ibuprofen can have side effects. I just wondered if anyone knew of a
weekly dose that would be acceptable or at the very least a little
safer. Than-you.
Evelyn Ruut - 10 Nov 2006 13:06 GMT
> Hi, I've just joined this group. Although my mum hasn't been diagnosed,
> she seems to be showing symptoms of mild cognitive impairment for the
[quoted text clipped - 6 lines]
> weekly dose that would be acceptable or at the very least a little
> safer. Than-you.
As Dennis just mentioned in another reply, it is imperative that you have
her thoroughly tested because there are TREATABLE causes of some memory
loss. Not all, of course, but you owe it to yourself and your mom to find
out just exactly what is the cause. It can be something as simple as an
adjustment to her thyroid meds or as simple as taking a certain B vitamin.
There is also a problem called NPH, which is short for Normal Pressure
Hydrocephalus, also reversible. Alzheimers and mini strokes are other
causes, and they are not reversible, sadly. In any case, a complete
gerontological workup is needed to discover what the problem is.
If your mother is developing alzheimers, you will need to get certain legal
matters in order so you can make decisions on her behalf.
I sympathize with your tears. We have all been through it around here. I
truly hope you find some answers and that with those answers comes some
help.

Signature
Best Regards,
Evelyn
(to reply to me personally, remove 'sox')
Greg - 11 Nov 2006 18:03 GMT
Dear Evelyn, Thank you for your reply. I live in the UK and I did
wonder if it was the thyroid meds that needed looking into and one of
her blood tests showed the TSH levels high and yet the next blood test
was 'normal'. The Doctor referred us to an endocrinologist who was
angry because she'd been taking a slightly increased dose of thyroxine
for a week to see if it made any difference and he just referred her to
a memory clinic saying it wasn't the thryoid - wasn't very impressed
with him. She's been taking ibuprofen for a week as I say and also
Vitamin B12 and folic acid just in case the homocystine levels are
high. I know we should probably go onto the memory clinic but mum gets
so nervous having appointments and upset. I don't know what NPH is but
i'll look it up on the internet. Thanks, Greg.
Evelyn Ruut - 11 Nov 2006 18:07 GMT
> Dear Evelyn, Thank you for your reply. I live in the UK and I did
> wonder if it was the thyroid meds that needed looking into and one of
[quoted text clipped - 8 lines]
> so nervous having appointments and upset. I don't know what NPH is but
> i'll look it up on the internet. Thanks, Greg.
Greg, her getting anxious over appointments is VERY typical of alzheimers, I
hate to tell you. My mother in law would obsess and get anxious for days
beforehand. We got so that we wouldn't tell her till almost the last
minute that she had any appointment. It was easier on her that way. You
should make the appointment, but only tell her that day, and say that you
thought you'd told her or something.

Signature
Best Regards,
Evelyn
(to reply to me personally, remove 'sox')
Mary_Gordon@tvo.org - 11 Nov 2006 00:07 GMT
Greg, oh my goodness
If you think even for a nanosecond that she is developing Alzheimer's,
get her to a doctor for a proper examination. How do you think AD
starts? With vague slight symptoms, exactly as you describe.
She needs proper assessment. There are many causes of cognitive
impairment. There are medications that can genuinely help slow down the
progess of many dementias, and there are some that are treatable (i.e.
reversable) although AD is not among them. You have to know what you
are dealing first, before you can figure out what you might be able to
do to help.
Don't mess with ibuprofen, see the doctor!!!
Mary G.
jp - 11 Nov 2006 10:07 GMT
Greg,
Given that poorly-controlled hypothyroidism can cause signs similar to
dementia and NSAIDs such as ibuprofen can suppress thyroid function, I'd
suggest you take your mum to a doctor first.
Jack
> Hi, I've just joined this group. Although my mum hasn't been diagnosed,
> she seems to be showing symptoms of mild cognitive impairment for the
[quoted text clipped - 6 lines]
> weekly dose that would be acceptable or at the very least a little
> safer. Than-you.
Alan Meyer - 15 Nov 2006 01:07 GMT
Hello Greg,
I'm sorry to hear of your mother's problem.
I will second the advice everyone has given you about having
your mom diagnosed by a competent specialist. Finding
really competent, caring, open minded doctors can be very
difficult everywhere (it's difficult in the States too), but I
hope that the memory clinic you were referred to has some.
As for ibuprofen, it is my understanding that various types
of anti-inflammatory agents have shown some effect in
delaying the onset of Alzheimer's Disease.
Ibuprofen is one such agent. Curcumin (curry powder) is
another which may have fewer side effects. The effects
have been seen in test tubes, in mice, and in humans, but
I have not seen any hard data on how large the effect is
or what dose is required. Some say very small doses
are adequate to get all the benefit you can get from these
agents.
If you want to research these things, try going to Pubmed
(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed)
and searching for (alzheimer's disease ibuprofen) or
(alzheimer's disease nsaid), etc.
One thing I think I can say for certain is that if your Mom
has Alzheimer's, ibuprofen won't cure her and won't keep
her from getting worse. My Mom, Dad, and Mother-in-Law
all suffered from dementia and all took lots of ibuprofen.
Alan
Mary_Gordon@tvo.org - 15 Nov 2006 02:23 GMT
Hi Alan,
To chime in on what you said, my MIL took all kinds of
anti-inflamatories (prescription and otherwise) since she had really
terrible arthritis in her knees, which had been getting worse over 20
years to the point where she really should have had knee replacements
done in her late 60's.
All those pills didn't stop her from a diagnosis of AD at the
relatively young age of 73, or stop the AD from taking her life before
her 80th birthday.