Medical Forum / Diseases and Disorders / Alzheimer's / August 2006
Diet & behaviour changes
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Jim - 19 Aug 2006 22:29 GMT Has anyone noted or got any info on behaviour changes induced by diet in dementia?
I know I'm kinda clutching at straws but I was looking after my father for a few hours the other day. He was "good" when I arrived. He recognised me, smiled, was generally compliant as I helped him to the toilet etc.
I'd brought some good individual steak pies for lunch and he clearly enjoyed his pie greatly. However, within 30 minutes of eating his lunch, his behaviour changed completely.
He developed an obsessive fixation that he was being kept away from his "real" home, didn't recognise anyone anymore. Despite severe phisical disabilities he started trying to break down doors, lashing out physically and generally behaving in a paranoid and aggressive manner. After a couple of hours he calmed down a bit.
Now this kind of behaviour isn't that unusual for him but this was the first time I'd seen it come on so quickly and so closely associated with eating (which may of course just have been pure coincidence). Still, if there may be a known dietary effect that is aggravating things (many too much protein or something?) I'd like to know more.
Anyone seen anything similar?
(FWIW, although my father has been diagnosed with Alzheimer's, his disease progress isn't really typical and is really more like vascular dementia. He's 81)
Jim
Dana Carpender - 19 Aug 2006 22:42 GMT > Has anyone noted or got any info on behaviour changes induced by diet in > dementia? [quoted text clipped - 24 lines] > progress isn't really typical and is really more like vascular dementia. > He's 81) Certainly food sensitivities can cause mental symptoms. I've just been reading this: http://tinyurl.com/m3yts -- very interesting stuff, and it does, indeed, mention mental symptoms from gluten sensitivity. (Your pies would have had gluten in the crust and gravy, no doubt.)
Not saying gluten is the thing (though it bears looking at,) but simply that yes, mental symptoms from food sensitivities are not at all unknown, and often go undiagnosed.
Dana
ironjustice@aol.com - 20 Aug 2006 01:57 GMT >>Jim wrote: Now this kind of behaviour isn't that unusual for him but this was the first time I'd seen it come on so quickly and so closely associated with eating (which may of course just have been pure coincidence). Still, if there may be a known dietary effect that is aggravating things (many too much protein or something?) I'd like to know more.
Anyone seen anything similar?<<
Heard .. of similar ..
Vascular dementia .. lack of blood flow .. immediate induction .. of .. violent behavior ..
Alzheimers' .. problems / cognition seem to stem somewhat from the inability of the blood to flow properly to the brain .. evidenced by improvement by the use of blood thinners.
If one were to wish to do a home based study of this .. phenomenon .. one 'could' prepare a fat based meal for your father.
They have shown a fat based meal is able to increase the viscosity pretty .. quickly.
Soooo ..
Blood Flow to Heart Hampered After High-Fat Meal Mon Apr 1, 5:54 PM ET
NEW YORK (Reuters Health) - While a lifetime of fatty meals can lead to
a heart attack, a study released Monday suggests that chowing down on just one high-fat meal can interfere with blood flow to the heart in healthy young men.
In the study, 15 healthy men in their 20s or early 30s consumed a shake
containing a whopping 1,200 calories and 100 grams of fat--roughly the equivalent of eating a fast-food meal plus dessert. All of the men underwent a heart test and had blood samples taken before and after consuming the liquid meal.
The researchers, led by Dr. Takeshi Hozuml of Osaka City University in Japan, found that 5 hours after the high-fat meal, the ability of heart
arteries to expand and increase blood flow to the muscle--a measure known as coronary flow reserve--dropped by 18%.
In addition, five men underwent the same tests after consuming a low-fat 1,200 calorie meal that contained only 10 grams of fat. In that case, the men did not have a drop in coronary flow reserve after consuming the meal, according to the report in the April issue of the Annals of Internal Medicine.
The findings suggest that coronary microcirculation--the tiny blood vessels that provide oxygen-rich blood to heart muscle--can be impaired by a high-fat meal. Although the study did not include people with heart disease, the results could explain why those with heart disease-related chest pain, known as angina (news - web sites), can have increased pain after a high-fat meal. The pain of angina is thought to be due to a reduction in blood flow to the heart.
The heart, the body's blood pumping organ, requires its own blood supply to function properly. Coronary arteries are the main blood vessels that supply the blood to the heart, and if a blockage occurs the surrounding vessels compensate by expanding in size to keep the proper amount of blood flowing to the heart.
Doctors have know that a high-fat meals, which increase the amount of fatty substances in the blood such as triglycerides, can over time lead to artery clogging and eventually heart attacks. In the new study, the investigators found that triglyceride levels jumped from 140 milligrams per deciliter of blood (mg/dL) after the high-fat meal, but only 10 mg/dL after the low-fat meal.
While the researchers were not able to determine if the increase in triglyceride levels was responsible for the decrease in the heart's blood flow reserve, the authors say the findings suggest implications for patients with heart disease.
SOURCE: Annals of Internal Medicine 2002;136:523-528.
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Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
neo-dimwit - 20 Aug 2006 16:15 GMT Weird. You seem to be suggesting that I prepare a deliberately toxic meal for my dad.
Jim
>>> Jim wrote: > [quoted text clipped - 106 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk Dennis P. Harris - 21 Aug 2006 03:52 GMT > Weird. You seem to be suggesting that I prepare a deliberately toxic meal > for my dad. mr. ironjustice is a crank who has been killfiled by most of the regulars.
ironjustice@aol.com - 22 Aug 2006 00:03 GMT >>neo-dimwit wrote: Weird. You seem to be suggesting that I prepare a deliberately toxic meal for my dad.<< - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
<<snip>> the equivalent of eating a fast-food meal with dessert .. <<snip>>
You .. figure .. taking your dad out for a .. fast food meal .. with dessert .. is going to .. kill .. him ..
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Dennis P. Harris - 20 Aug 2006 06:39 GMT > (FWIW, although my father has been diagnosed with Alzheimer's, his disease > progress isn't really typical and is really more like vascular dementia. > He's 81) sounds like time for a second opinion...
Tumbleweed - 20 Aug 2006 08:21 GMT > Has anyone noted or got any info on behaviour changes induced by diet in > dementia? [quoted text clipped - 26 lines] > > Jim I think its **far** more likely to have been a pure coincidence. For example, whats so important about 30 minutes in your mind? What did he do an hour before? Trip over? Maybe it was that. 2 hours? See a story on the TV? Maybe it was that. 1 minute or 14 minutes before? What exact phrase did you say to trigger his behaviour?
IMHO this is a great example of the capability of the human brain to jump to unwarranted conclusions, you have associated one thing that happened previously with another that happened later, without any good reason, especially as this isnt the first time its happened, when I started reading it sounded as if he had never had this type of behaviour before and it was completely 'out of the blue'. It could have been caused by a myriad of things (all more likely than a steak pie!), external or internal, including a vital neuron failing.
Dont worry about diet, go to the doc and enquire after medicines that may be able to manage these type of delusions. Though from what you have reported they may not be much help, since I suppose in a way they arent 'delusions', eg he isnt just imagining that things are occurring like people trying to kill him, he has just lost his memory and is now back (in his mind) where he was say 50 years ago, he doesnt know who you are or where he is so he is logically trying to escape just like you would if you found yourself in a strange house with people you didnt know who insisted you lived there and couldnt leave.
This may just be a sign of things to come and you should expect more behaviour of this type. After all, initially he had very few and very mild examples of this type of behaviour, and over time they have increased to more frequent and more serious. Now you have witnessed a very serious example, and you aren't (I apologise for saying this) thinking clearly, instead of looking at the big picture (gradually increasing severity and frequency to a point where he is getting out of your ability to manage) you have fixed on one episode as if that is the problem, rather than the real problem, 'dads getting much worse, what should we do if he's like this all the time?".
I hope you are considering how he can be managed if (as sounds likely) these episodes get more frequent and more violent. Who normally cares for him?
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
neo-dimwit - 20 Aug 2006 16:18 GMT Typical usenet. Don't bother trying to answer the question, just make a bunch of assumptions and give the answer you wanted to give.
A simple "No, I have no personal experience of that" would have sufficed.
Jim
>> Has anyone noted or got any info on behaviour changes induced by >> diet in dementia? [quoted text clipped - 65 lines] > likely) these episodes get more frequent and more violent. Who > normally cares for him? Tumbleweed - 20 Aug 2006 17:33 GMT If you want a direct answer to a question, usenet is the wrong the place to go! As you appear to know, so even more bizzarre you'd ask a q if you only wamted 'y' or 'n' as the answer.
BTW, what assumptions did I make?
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
> Typical usenet. Don't bother trying to answer the question, just make a > bunch of assumptions and give the answer you wanted to give. [quoted text clipped - 72 lines] >> likely) these episodes get more frequent and more violent. Who >> normally cares for him? Alan Meyer - 27 Aug 2006 18:15 GMT Jim,
I think Tumbleweed's answer is worth re-reading.
It's easy to focus on two events that occurred together and assume that one caused the other when in fact there is no connection. TW was just pointing this out. If you ask 100 people if their AD parent has ever had a bad episode after a big meal, I would expect the answer to be Yes for 90 of them. If you ask them if the parent ever had a bad episode after a small meal, before a meal, or when hungry, the answer would also be Yes for 90 of them.
The answers just don't tell us whether there is a causative association or not.
The additional point TW made was that, if your Dad has Alzheimer's Disease, you're going to see more and more of this. Your original question was a fine one. Nothing wrong with it. But TW is suggesting that you may not want to put too much energy into pursuing it. A bigger issue is what is to be done about the behavior.
Alan
> Typical usenet. Don't bother trying to answer the question, just make a bunch of > assumptions and give the answer you wanted to give. [quoted text clipped - 71 lines] >> likely) these episodes get more frequent and more violent. Who >> normally cares for him? Tumbleweed - 27 Aug 2006 22:50 GMT Actually I think _your_ answer is worth reading, much more succinct than my rambling one :-)
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
> Jim, > [quoted text clipped - 97 lines] >>> likely) these episodes get more frequent and more violent. Who >>> normally cares for him? Mary_Gordon@tvo.org - 21 Aug 2006 00:21 GMT Jim,
You could test this easily enough - just give him the same meal elsewhere and see what happens.
I strongly suspect it has nothing to do with food, since in 30 minutes, he wouldn't have digested the food yet - he might have had time for an allergy, but not for "too much protein" or anything else along those lines.
He's got brain damage that is interfering with his ability to recognize places, people and objects - its pretty common at that stage for them to think someone has taken away the "real" item, and replaced with a fake or imposter. That has to be really scary. You say he also has catastrophic reactions (i.e. flip outs), which is also common - he has a very limited ability to cope with change, new information, demands, stress etc.
So - just being in your house out of his familiar surroundings for a few hours might be enough stress to set him off if he's not having a great day, particularly if you've been doing things with him like getting him cleaned up, feeding him etc. The stress of all that might be cumulative, and pow!
M.
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