Medical Forum / Diseases and Disorders / Alzheimer's / July 2006
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Easter - 18 Jul 2006 18:21 GMT Go to the home page of your webtv and read about alzheimers....It runs in famlies..But there is help for you if you get started earley....If it's in your family you get it....and the diabetes goes with the alzhiemers we know that now.....but they have a new drug to help it....called Avandia...But what I was trying to tell you is the medecine for diabetes will actually help the alzheimers patient..........
Tumbleweed - 18 Jul 2006 22:05 GMT > Go to the home page of your webtv and read about alzheimers....It runs > in famlies..But there is help for you if you get started earley....If [quoted text clipped - 4 lines] > >> Easter Stephens Did you tell us what the drug is called? Lots of drugs for diabetes. And, your one anecdotal report, sorry to say, isnt regarded as proof, how do you, or anyone else, know what the progression of your Az would be without it? maybe it would be slower without it, we dont know and neither do you! Any studies you are aware of? Dont take this the wrong way, I'm sure you mean well, but many many people, well meaning and otherwise, tell us every week about a new 'cure'. If only 1% of those were right, there would be no one with Az any more, as they'd all be cured.
Oh, I dont recall (LOL) if you mentioned it, but what Az medicine are you on?
p.s. Only a few types of Az run in families, most dont.
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
Easter - 19 Jul 2006 00:36 GMT I take Aricept and nemenda.....But for the last few days webtv is telling us Things that I didn't know.... Like Azheimers and Diabetes go together if you get one you get both...But the Glucophage I take for my dibetes is helping my Alzhiemers...I have had it 6years I may not be too bright but I know what I read.... and no one is listening.....
Bud - 19 Jul 2006 01:01 GMT >...but I know what I read.... and no one is listening..... Yes we are, Easter. Just don't got nothin' to add yet.
Easter - 19 Jul 2006 03:22 GMT Thanks Bud...At least your listening....
Tumbleweed - 19 Jul 2006 08:30 GMT >I take Aricept and nemenda.....But for the last few days webtv is > telling us Things that I didn't know.... Like Azheimers and Diabetes go [quoted text clipped - 3 lines] > >> Easter Stephens From what I read, it appears that if you get diabetes the chances you'll get Az may be higher (but not the other way round). And there are no studies regarding Glucophage and Az. I'm not saying it _wont_ slow it down, just that one anecdotal report is not good enough to announce a medical breakthrough. Otherwise, we'll also have to stop wearing shoes, start taking neem oil, etc etc.
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
~karen~ - 19 Jul 2006 10:30 GMT >>I take Aricept and nemenda.....But for the last few days webtv is >>telling us Things that I didn't know.... Like Azheimers and Diabetes go [quoted text clipped - 10 lines] > breakthrough. Otherwise, we'll also have to stop wearing shoes, start taking > neem oil, etc etc. I heard a couple of "blurbs" on the news about this myself. I found an article from Reuters July 17th that explains what Easter apparently has read about. ------------------ By Maggie Fox, Health and Science Correspondent
WASHINGTON (Reuters) - Diabetes and pre-diabetic conditions appear to worsen the risk of Alzheimer's disease but drugs that help regulate blood sugar may help patients with dementia as well, researchers report.
Several studies presented at a meeting in Madrid, Spain, this week show that patients who take some of the drugs commonly prescribed to type-2 diabetes were less likely to have Alzheimer's disease. -------------------- The article goes on to emphasize the concern that the Alz. community has regarding the possible link to diabetes and the ever expanding cases of people diagnosed with diabetes daily. They are expecting (if the link between diabetes and Alz. is true) an equally expanding number of Alz. cases within the baby boomers. I didn't read any further to see which specific medications for diabetes were helping with Alz. also.
~karen~
Easter - 19 Jul 2006 00:55 GMT I told you I take Nemenda morning and evening And Aricept in the evening for my alzhiemers,,,,and Glucophage ''metforim'' for my dibetes morning and evening and they have discovered that the Gluophage we take for diabetes is actually helping the alzhiemers.. I've told you that and it runs in families....and also an artical in the paper that said they have a new drug called Avendia or close.... and it helps to keep the crap that grows on your brain from growing... they have had articals on our home page every day for a while about alzhiemers and diabetes...... and if you get one you get the other but the gloucophge actually helps clean the brain as it works for diabetes.....O forget it ''know it all""
Easter - 19 Jul 2006 01:03 GMT My dad had it....one of his brothers and 1 sister And I have a sister that has it and is totally blank and doesn't talk at all... and her sisters have her in the nursing home....I have had it 6years i'm trying to tell you and still able to drive and keep house....and take care of my self....try reading the home page once in awhile....
Chuck Whealton - 19 Jul 2006 02:05 GMT > My dad had it....one of his brothers and 1 sister And I have a sister > that has it and is totally blank and doesn't talk at all... and her [quoted text clipped - 16 lines] > > --WebTV-Mail-3059-23868-- Easter:
Whatever you're doing, if your other normally prescribed pharmaceuticals are helping you with your AD, that's great. Six years is a long time and I hope you have many, many more without getting worse, and hopefully, actually getting better.
I've seen the articles linking diabetes and AD.
Good luck and I hope we'll be seeing you around for a good, long time.
Charles R. Whealton Charles Whealton @ pleasedontspam.com
Easter - 19 Jul 2006 03:24 GMT June - 19 Jul 2006 14:34 GMT My dad had it....one of his brothers and 1 sister And I have a sister that has it and is totally blank and doesn't talk at all... and her sisters have her in the nursing home....I have had it 6years i'm trying to tell you and still able to drive and keep house....and take care of my self....try reading the home page once in awhile....
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Easter Stephens
Easter.....There are so many kinds of Alz and the longer you can hang in there, the better chance you can be here for a cure. My mother drove a car, played bridge and took care of herself for at least 8 years. Lived alone some 4 more years and is now in independent assisted living. She can still use the phone, and get around her assisted living without help. She took only Aricept but it wasn't available when she was first diagnosed in '93. You're right about alz running in families. My sisters-in-law both have asked me about it. They have no first hand knowledge about alz (and they're in their late 70's and early 80's) even though many family members have lived into their 90's and their mother 101. Nobody had alz. Wishing you the best....June
Tumbleweed - 19 Jul 2006 16:48 GMT "Easter" <beggarjean@webtv.net> wrote in message news:22751-44BD76E4-2221@storefull-3117.bay.webtv.net... My dad had it....one of his brothers and 1 sister And I have a sister that has it and is totally blank and doesn't talk at all... and her sisters have her in the nursing home....I have had it 6years i'm trying to tell you and still able to drive and keep house....and take care of my self....try reading the home page once in awhile....
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Easter Stephens
Easter.....There are so many kinds of Alz and the longer you can hang in there, the better chance you can be here for a cure. My mother drove a car, played bridge and took care of herself for at least 8 years. Lived alone some 4 more years and is now in independent assisted living. She can still use the phone, and get around her assisted living without help. She took only Aricept but it wasn't available when she was first diagnosed in '93. You're right about alz running in families. My sisters-in-law both have asked me about it. They have no first hand knowledge about alz (and they're in their late 70's and early 80's) even though many family members have lived into their 90's and their mother 101. Nobody had alz. Wishing you the best....June
==================== She is _not_ correct about Az running in families, (except for one or two rare types.)
50% of people aged over 85 have Az, with a statistic like that its no wonder people can point to 'clusters' of Az in families that 'prove' to them that it runs in families. It doesnt.
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
June - 19 Jul 2006 20:12 GMT > "Easter" <beggarjean@webtv.net> wrote in message > news:22751-44BD76E4-2221@storefull-3117.bay.webtv.net... [quoted text clipped - 28 lines] > wonder people can point to 'clusters' of Az in families that 'prove' to > them that it runs in families. It doesnt. Trust me I want to believe that it doesn't run in families. I know they can't "prove" it runs in families. When my mother was first diagnosed, the doctor asked about other family members and she realized she had lived longer than anyone else and has now outlived her 5 younger brothers. In my husband's family (MIL was one of ten children born to her father's second wife, first wife had 13 children) almost all of them (the women) live to be in their upper's 70's and some have reached 100 and I've not heard of any dementia other than my MIL at just before she died at 101 and I'm sure it was TIAs. A sister died a few months later at the age of 100. If you have a family with a history of long life spans and no dementia, it has to make you wonder......June
Tumbleweed - 19 Jul 2006 21:41 GMT > Trust me I want to believe that it doesn't run in families. I know they > can't "prove" it runs in families. Maybe thats because it doesnt?
> When my mother was first diagnosed, the doctor asked about other family > members and she realized she had lived longer than anyone else and has now [quoted text clipped - 5 lines] > months later at the age of 100. If you have a family with a history of > long life spans and no dementia, it has to make you wonder......June People are _extremely_ poor at extrapolating from a few isolated instances to the general case, or picking out associations, as your statement shows. Thats why they killed people for being witches no too long ago in your country 'oh I miscarried and that old woman looked at me nastily, must be her fault".
You simply _cannot_ validly take what has happened to maybe ?10? people you happen to know out of tens or even hundreds of millions, and make a case! Look at Easter who has posted that becase she has been taking medicine 'X' and had Az for 6 years, therefore its the medicine 'X' that is the reason she is still OK after 6 years. What about the fact we dont know the 'natural' course of the disease, or the fact that she is **taking medicines proven for Az**, or the hundreds of other factors applicable to her (does she still wear shoes for example?), that might be the reason??!!
The point is, that with the huge number of cases of Az, even if there was a slight association, it would have shown up long ago. Apart from a few rare types (mostly early onset IIRC), it hasnt. If there is one, it _must be_ slight, and more than outweighed by other factors such as environment, lifestyle and so forth.
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
Evelyn Ruut - 19 Jul 2006 21:48 GMT >> Trust me I want to believe that it doesn't run in families. I know they >> can't "prove" it runs in families. [quoted text clipped - 32 lines] > be_ slight, and more than outweighed by other factors such as environment, > lifestyle and so forth. One cannot argue with someone who has admittedly been diagnosed. No she doesn't make a lot of sense (Easter) but you have to hand it to her that she tries.
I don't think it "runs in families" but there MAY be a hereditary factor involved. I didn't also think it was fair game to mention that there are many elderly people who develop diabetes as they age, or that there are medications used in alzheimers which are known to affect blood sugar levels. It is far more complicated than any of us here can possibly address. Some of the best minds are working on these problems and haven't come up with clear answers.
 Signature Best Regards,
Evelyn (to reply to me personally, remove 'sox')
Easter - 20 Jul 2006 15:21 GMT Why do you think it would hit 3 people from one family.... And thier family before us....My dad and three brothers and 1sister I think and now me and my sister.....It has been in the news papers and on Webtv....
Evelyn Ruut - 20 Jul 2006 15:34 GMT Why do you think it would hit 3 people from one family.... And thier family before us....My dad and three brothers and 1sister I think and now me and my sister.....It has been in the news papers and on Webtv....
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Easter Stephens
There is a hereditary factor, but all alzheimers is not hereditary. I believe that a certain gene has been identified, but not in all cases.
--
Best Regards,
Evelyn (to reply to me personally, remove 'sox')
Dennis P. Harris - 21 Jul 2006 02:48 GMT > Why do you think it would hit 3 people from one family.... And thier > family before us....My dad and three brothers and 1sister I think and > now me and my sister.....It has been in the news papers and on Webtv.... which does NOT make it true. newspapers get things wrong all the time.
Tumbleweed - 21 Jul 2006 17:00 GMT >> Why do you think it would hit 3 people from one family.... And thier >> family before us....My dad and three brothers and 1sister I think and [quoted text clipped - 3 lines] > which does NOT make it true. newspapers get things wrong all the > time. ...and it will be a cold day in Hell before I use something on WebTV as a scientific reference!
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
Tumbleweed - 21 Jul 2006 16:59 GMT > Why do you think it would hit 3 people from one family.... And thier > family before us....My dad and three brothers and 1sister I think and > now me and my sister.....It has been in the news papers and on Webtv.... > > Easter Stephens random chance. there are millions of families, there will be many like yours and many the opposite, its just down to luck unless you have the specific type that is genetic. Or did you think that 50% chance means that if there are 4 people, then 2 of them _must_ have it? Chance doesnt work that way Easter.
oh, and 'what exactly has "been in the newspapers and on Webtv"?
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
Dana Carpender - 21 Jul 2006 18:39 GMT >>Why do you think it would hit 3 people from one family.... And thier >>family before us....My dad and three brothers and 1sister I think and [quoted text clipped - 7 lines] > are 4 people, then 2 of them _must_ have it? Chance doesnt work that way > Easter. Well, and since there does appear to be an Alzheimer's/diabetes connection, there may well be a genetic link, just as there is with diabetes and other carbohydrate-driven health problems -- Type II diabetes is one of those things where genetics loads the gun, and diet and lack of exercise pull the trigger.
Would also explain the increasing rate of Alzheimer's -- Type II diabetes is skyrocketing as well, from our vast consumption of bad food and our sedentary lifestyle. If Alzheimer's is, indeed, a type of diabetes, then you'd expect it to increase at the same time and at a similar rate.
Dana
Tumbleweed - 21 Jul 2006 18:57 GMT >>>Why do you think it would hit 3 people from one family.... And thier >>>family before us....My dad and three brothers and 1sister I think and [quoted text clipped - 13 lines] > is one of those things where genetics loads the gun, and diet and lack of > exercise pull the trigger. Could be. THough for Az, pretty much all common ythings like that, including diet, seem to be ruled out. I wonder if they checked for an association with the foods that typically are thought to be associated with diabetes?
> Would also explain the increasing rate of Alzheimer's -- Type II diabetes > is skyrocketing as well, from our vast consumption of bad food and our > sedentary lifestyle. If Alzheimer's is, indeed, a type of diabetes, then > you'd expect it to increase at the same time and at a similar rate. > > Dana You would, I wonder if anyone has done a study on that? Howoever you'd need somehow to control for the effect of aging. Life expectancy is, or has been, increasing. That alone would increase Az, in the same way that, say, cataracts would increase if the population lived longer, simply that there is more time to get them!
As you say, if diabetes and Az are linked then that would also increase the amount of Az (though all I've seen recently are _many_ reports of the same _single_study, which itself was of a very atypical population, plus the numbers weren't actually that great, under 1,000 people IIRC. Would be interesting to see some more larger scale studies.
Plus of course, if there is a link, as you alluded, its possible its not the diabetes that cases Az, but some other factor, eg 'X' causes diabetes _and_ Az. I would expect to see some definitive answers on this pretty soon, since on one hand, if the link is as large as the reported study found, it should show up right away, OTOH if it _is_ as clear as the study says, why hasnt it shown up already? If there was a straightforward genetic link it would have been proven by now. The fact it hasnt been, means it must be slight. Something strange going on here in either case.
BTW, from what I read, the supposition was not that diabetes was a form of Az, IIRC it was that one of the side effects of diabetes was to increase the amount of protein (or whatever it is) that accumulates in the brain and is thought to cause Az (again, its not actually 100% clear that the accumulation is the cause, rather than for example, a side effect of something else.
Bottom line, there is a sh*t load of stuff we dont know, and simplistic headlines on WebTV repeated here by well meaning people (without even a teeny understanding of statistics & chance) aren't equivalent to knowing whats going on.
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
Beth Cole - 21 Jul 2006 19:21 GMT > Well, and since there does appear to be an Alzheimer's/diabetes > connection, there may well be a genetic link, just as there is with > diabetes and other carbohydrate-driven health problems -- Type II > diabetes is one of those things where genetics loads the gun, and diet > and lack of exercise pull the trigger. *shrug* I haven't met anyone to date with Alzheimer's who also has diabetes, either Type I or II. My MIL is quite literally perfectly healthy other than the fact her mind is gone (other than the TB as a young adult, she's been hospitalized for 2 babies, a roller skating accident & a stroke). My grandfather had perfect blood sugars his entire life. He did have some heart & prostate problems, but both were more linked to age than to anything else. The numerous other relatives I've known who were diagnoses had no indication of diabetes, either.
I'm yet not convinced that Alzheimer's is linked to anything else, because we don't know what causes the onset. Once we can find that, we will undoubtedly find links to other things.
Beth
 Signature Don't go around saying the world owes you a living. The world owes you nothing. It was here first. ~Mark Twain
Easter - 21 Jul 2006 19:35 GMT I sent it to you and you wouldn't accept it...the medecine I take for diabetes actually works to keep the crap from growing on your brain...and and a new drug called avanda is actually cleaning the damage from the brain......I'm not sure if it is for blood pressure or diabetes... had it in my head and lost it....
Tumbleweed - 21 Jul 2006 20:22 GMT >I sent it to you and you wouldn't accept it...the medecine I take for > diabetes actually works to keep the crap from growing on your [quoted text clipped - 3 lines] > >> Easter Stephens Thanks to the crapness of webtv, which I assume is responsible for snipping the entire content of the message you relied to, I have no idea what you sent to me. But as a I recall, you have never posted a reference to the 'well known' fact that Az runs in families except to say 'its on webtv'. Thats no use to me as I dont have it, and I suspect, even if I did, that that answer is like saying 'its on the internet'.
Also, seems to me there's a contradiction here. Given that there is supposedly a link between Az and Diabetes, and most people on diabetes will be taking medicine for it, then either .....if the medicine fixes Az, there _wouldnt_ be a high association between the two (since the medicine would prevent Az), or if the medicine didnt fix Az, the link would show up but you wouldnt be able to say the medicine was responsible for your 6 year slowness in decline*. Would seem unlikely to have both, eg medicine that prevents Az _and_ higher incidence of Az.
*Not to mention the fact you may not even have Az, the only sure way of knowing is an autopsy. There are many other diseases and conditions that have similar symptoms. Not to mention the fact that people can have a slow decline, everyone is different. Maybe some other people with a 6 year slow decline go swimming every day or have a garlic tablet or do the crossword or take neem oil. Maybe they are responsible?
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
June - 19 Jul 2006 23:42 GMT Ok Tumbleweed ....My brain agrees with you but my psyche doesn't . I keep telling myself that just because my mother has it, doesn't mean I will get it. I try not to dwell on it. I'm sure many here feel the same....June
>> Trust me I want to believe that it doesn't run in families. I know they >> can't "prove" it runs in families. [quoted text clipped - 13 lines] > be_ slight, and more than outweighed by other factors such as environment, > lifestyle and so forth. Tumbleweed - 20 Jul 2006 07:43 GMT > Ok Tumbleweed ....My brain agrees with you but my psyche doesn't . > I keep telling myself that just because my mother has it, doesn't mean I > will get it. I try not to dwell on it. I'm sure many here feel the > same....June If you make it to 85, you have a 50% chance of getting it, just like the rest of us!
 Signature Tumbleweed
email replies not necessary but to contact use; tumbleweednews at hotmail dot com
June - 20 Jul 2006 14:27 GMT If I make it to 85 before alz ,then I figure that as lucky. I figure they will either have a cure or an immunization for it by then. Mom got it at 73 and that's not so far away. As you know women tend to get it about 10 years earlier than men....June
>> Ok Tumbleweed ....My brain agrees with you but my psyche doesn't . >> I keep telling myself that just because my mother has it, doesn't mean I [quoted text clipped - 3 lines] > If you make it to 85, you have a 50% chance of getting it, just like the > rest of us! ladylove77 - 20 Jul 2006 02:49 GMT My father-in-law had AD, and my husband and both of his brothers had/have dementia. Maybe it doesnt run in families, but it has covered that one pretty well! Gwen
>> Trust me I want to believe that it doesn't run in families. I know they >> can't "prove" it runs in families. [quoted text clipped - 32 lines] > be_ slight, and more than outweighed by other factors such as environment, > lifestyle and so forth.
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