insulin like`growth factors
--------------------------------------------------------------------------------
a recent study suggests these may be helpful in treating the disease. Is
there any way to obtain these for patients. Are they taken by injection
only.
Tumbleweed - 03 Mar 2006 08:07 GMT
> insulin like`growth factors
> --------------------------------------------------------------------------------
> a recent study suggests these may be helpful in treating the disease. Is
> there any way to obtain these for patients. Are they taken by injection
> only.
If you took every chemical that a 'study' indicated would be useful in Az,
you'd probably be unable to physically do it, not enough time in the day,
and the side effects would probably kill you within the day anyway. A single
study does not a cure make.
There are even disagreements about drugs that do have an effect, whether
they are worthwhile, let alone one off studies that usually apply to
something entirely unlike an actual proven preventative/cure/treatment, such
as;
1 cells in a test tube
2 mice
3 a study of 15 people over 6 months showing a 3% higher than chance that
people got 0.1% better.
4 something unadjusted for all contributory factors ...for example, people
in country x have less than Az than people in country y, people in country x
eat more (or less) of substance z, "therefore" substance z
cures/prevents/causes Az.
and finally
5. One-off studies that show an effect that is never replicated again by any
other study, for various reasons including pure chance, or a poor study.

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jgiustino - 04 Mar 2006 06:37 GMT
Can some one answer my question without the "lessons on research" That's
something I know better than you.
>> insulin like`growth factors
>> --------------------------------------------------------------------------------
[quoted text clipped - 22 lines]
> any other study, for various reasons including pure chance, or a poor
> study.
Tumbleweed - 04 Mar 2006 10:22 GMT
> Can some one answer my question without the "lessons on research" That's
> something I know better than you.
Are you psychic and know what my research background is?
No you cant be, or you'd know this was a very poor choice of group to be
posing your question to.

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Dennis P. Harris - 04 Mar 2006 18:15 GMT
> Can some one answer my question without the "lessons on research" That's
> something I know better than you.
if you're such a know-it-all, then you should be able to find
this miracle substance on your own, or make it yourself. this is
group for caregivers, not for miracle cure seekers.
W.M.McKee - 04 Mar 2006 18:43 GMT
>insulin like`growth factors
>--------------------------------------------------------------------------------
>a recent study suggests these may be helpful in treating the disease. Is
>there any way to obtain these for patients. Are they taken by injection
>only.
You can get sublingual spray of IGF-1 at most health food stores.
Additionally, in Canada and in New Zeland, velvet antler is available
in preparations that contain high concentrations of HGF-1.
Also, Green Lipped Mussel extract is available from New Zeland in
some preparations that also contain IGF-1. Among the nutrients in
Green Lipped Mussel extract are many vitamins, especially the B
complex group and a broad range of minerals and trace elements. It is
also rich in omega 3 fatty acids, protein, provides essential amino
acids and is an excellent, well balanced nutritious dietary
supplement.
Green Lipped Mussel extract is useful in alleviating inflammations and
arthritis...
I hope the foregoing is helpful.
Will
Mary_Gordon@tvo.org - 04 Mar 2006 23:51 GMT
I dunno about insulin like growth factors, but insulin itself doesn't
survive passing through the gut, which is why diabetics can't take
insulin orally.
Mary G.
wmmckee@cox.net - 06 Mar 2006 18:20 GMT
> I dunno about insulin like growth factors, but insulin itself doesn't
> survive passing through the gut, which is why diabetics can't take
> insulin orally.
>
> Mary G.
That's why it is available in a sublingual spray..... so that it can be
absorbed directly into the bloodstream.
I tried it for a while in connection with my diabetes, but it did nothing
for me that I could tell, so I stopped using it.
Will
Jo Ann Malina - 05 Mar 2006 13:13 GMT
jgiustino <jgiustino@shaw.ca> is alleged to have said:
> insulin like`growth factors
> --------------------------------------------------------------------------------
> a recent study suggests these may be helpful in treating the disease. Is
> there any way to obtain these for patients. Are they taken by injection
> only.
Here's one citation:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstra
ct&list_uids=16444902&query_hl=3&itool=pubmed_docsum
NIH is the National Institutes of Health, a US government agency.
I found this by Googling the words
IGF-1 alzheimer's
after the term IGF-1 turned up in a later post in this thread.
Repeating the search at the site above lists 69 citations.
The new inhaled insulin might help here, since the abstract talks about
a "small but consistent" memory improvement with intranasal insulin.
I don't know if it's available in Canada yet.

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Mary_Gordon@tvo.org - 05 Mar 2006 17:30 GMT
Inhaled insulin is ready to go, but isn't out YET. It won't be
available until midyear at the earliest.
http://www.diabetesnet.com/diabetes_treatments/insulin_inhaled.php
And then there is the question about whether any doctor would prescribe
inhaled OR injectable insulin for anyone who wasn't actually an insulin
dependent diabetic, or if inhaled insulin actually makes it into the
brain vs. the form of insulin the brain itself makes (i.e. the issue of
the brain/blood barrier).
I'm not saying there isn't hope, but I don't think we're quite there
yet. Insulin is not exactly benign in the hands of someone who doesn't
know exactly what they are doing. I doubt it would be hugely easy to
administer a puffer to someone in mid AD - I've certainly had the
experience of trying to get younger kids to use one for asthma, and its
a frustrating experience - and at least then, you aren't faced with a
little extra dose (due to fassing around trying to get them to breath
in at the right) putting someone into low blood sugar.
Mary
Dennis P. Harris - 06 Mar 2006 07:05 GMT
> I doubt it would be hugely easy to
> administer a puffer to someone in mid AD
and some folks never get the idea that you have to squeeze it
when you breath in. my mother was one of those, and as her
memory got worse, it became less possible, even with assistance.