Medical Forum / Diseases and Disorders / Alzheimer's / January 2006
3rd annual: Are shoes the cause of Alzheimer's disease?
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James Semmel - 05 Jan 2006 18:52 GMT TO: All Alzheimer's disease researchers, doctors, and patients.
I am a 35-year-old electrical engineer investigating the biomechanical effects of shoes on degenerative diseases. Each year I post about this admittedly unusual connection, but thus far nobody has taken it seriously.
Alzheimer's disease is just one example of diseases that are related to the use of footwear, especially since it affects women disproportionately more than men. Women's footwear is more physically deforming to the feet because of higher heels, pointier toes, and smaller sizes, but any shoe might have a more deforming effect on the lighter build of a woman's body. Even the first clinical case, presenting to Dr. Alois Alzheimer in 1901, was a woman called "Auguste D." who was born on May 16, 1850, during the last year that shoes were made completely by hand. Isaac Singer's sewing machine of 1851 made modern shoes widely available for the first time in the history of mankind. The second clinical case of what became known as Alzheimer's disease was a man, "Johann F." born about a year later on March 8, 1853. Both "Auguste D." and "Johann F." were among the first children growing up in the modern manufactured shoe era.
Chiropodist Dr. Simon J. Wikler pioneered efforts to understand the influences of shoes in the 1950's, but his work was neglected during the subsequent drug- and diet-based approaches to medicine. However, the prolific footwear historian and podiatrist Dr. William A. Rossi clearly demonstrated throughout his publications that shoes influence the posture of the human body. Therefore, using the posture-based approaches to medicine of the distinguished orthopedist Dr. Joel E. Goldthwait, I have expanded Dr. Wikler's insightful work to include a variety of illnesses and conditions whose causes remain unknown. You may find my thesis regarding shoes and disease on the Internet at:
http://www.shoebusters.com
My outlined treatment involves removing the cause, but resorting to wide-toed, soft-soled moccasins; regularly applying a contrast bath, or more descriptively, an alternate cold-hot footbath, to maintain flexibility in the feet; rehabilitation of the abdominal muscles, via forced exhalation, to balance the feet; and getting plenty of rest.
Thank you very much for considering my novel approach.
James Semmel Albuquerque, NM
Tumbleweed - 05 Jan 2006 19:18 GMT > TO: All Alzheimer's disease researchers, doctors, and patients. > [quoted text clipped - 5 lines] > Alzheimer's disease is just one example of diseases that are related to > the use of footwear <snip> I think you'll find that shoes with a high proportion of iron are even worse,and should they have aluminum buckles, you'll be lucky to get home from the store whilst wearing them.
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June - 05 Jan 2006 20:18 GMT > TO: All Alzheimer's disease researchers, doctors, and patients. > [quoted text clipped - 41 lines] > James Semmel > Albuquerque, NM Hmmmmm ...... This may us new insight about the "Old woman who lived in a shoe"
June
Dennis P. Harris - 06 Jan 2006 03:51 GMT > I am a 35-year-old electrical engineer investigating the biomechanical > effects of shoes on degenerative diseases. Each year I post about this > admittedly unusual connection, but thus far nobody has taken it > seriously. for a very good reason! because, of course, there is NO connection, and you are just a crank!
> Alzheimer's disease is just one example of diseases that are related to > the use of footwear, especially since it affects women > disproportionately more than men. yes, going barefoot is the answer, the only answer. yeah, sure, right. you loonies always have ONE cause for all diseases.
PLONK.
Tumbleweed - 06 Jan 2006 09:05 GMT Sense of humour / irony failure detected.
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> >> I am a 35-year-old electrical engineer investigating the biomechanical [quoted text clipped - 13 lines] > > PLONK. James Semmel - 06 Jan 2006 21:19 GMT Don't be too quick to dismiss the shoe theory. I know it seems unusual, but it's not that far-fetched.
The feet play a vital role in balancing the body, but shoes make that task much harder. Every organ in the body must likewise work harder.
In fact, of all the connections between shoes and human illness, I think that Alzheimer's disease is the most intriguing. It demonstrates the importance of the feet in determining our personality and behavior.
james
Evelyn Ruut - 06 Jan 2006 21:41 GMT When the only tool you have is a hammer, everything looks like a nail.
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Evelyn (to reply to me personally, remove 'sox')
> Don't be too quick to dismiss the shoe theory. I know it seems > unusual, but it's not that far-fetched. [quoted text clipped - 7 lines] > > james June - 06 Jan 2006 21:49 GMT > Don't be too quick to dismiss the shoe theory. I know it seems > unusual, but it's not that far-fetched. [quoted text clipped - 7 lines] > > james Especially foot in mouth.........June
Anthony Shipley - 07 Jan 2006 01:30 GMT >> Don't be too quick to dismiss the shoe theory. I know it seems >> unusual, but it's not that far-fetched. [quoted text clipped - 9 lines] > >Especially foot in mouth.........June Quite! (But some, other, posters should be 'quiet'!
anthony shipley
Run away with me; I can make you unhappy.
Anthony Shipley - 07 Jan 2006 01:26 GMT >In fact, of all the connections between shoes and human illness, I >think that Alzheimer's disease is the most intriguing. It demonstrates >the importance of the feet in determining our personality and behavior. And, of course, we shouldn't omit the the important statistical connection between the vast majority of people who have worn shoes all their lives but have never contracted A.D.
A more important connection is that between those with a brain and those without...
anthony shipley
Run away with me; I can make you unhappy.
Gwen Love - 07 Jan 2006 02:34 GMT Anthony, glad to see you still have your sense of humor! Gwen
>>In fact, of all the connections between shoes and human illness, I >>think that Alzheimer's disease is the most intriguing. It demonstrates [quoted text clipped - 11 lines] > > Run away with me; I can make you unhappy. Anthony Shipley - 07 Jan 2006 04:01 GMT >Anthony, glad to see you still have your sense of humor! >Gwen Thanks, Gwen. All I've got left is my cat and my naughty..
>>>In fact, of all the connections between shoes and human illness, I >>>think that Alzheimer's disease is the most intriguing. It demonstrates [quoted text clipped - 11 lines] >> >> Run away with me; I can make you unhappy. anthony shipley
Run away with me; I can make you unhappy.
Evelyn Ruut - 07 Jan 2006 04:14 GMT >>Anthony, glad to see you still have your sense of humor! >>Gwen > > Thanks, Gwen. All I've got left is my cat and my naughty.. A cat can be the best companion sometimes......:-) We have two of them around here...
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Evelyn (to reply to me personally, remove 'sox')
Gwen Love - 07 Jan 2006 04:59 GMT Catrs are much easier to care for than a dog, but I wouldn't trade my dog for anything. My son and daughter-in-law have 4 cats and 3 dogs. Too many animals for me! Gwen
>>>Anthony, glad to see you still have your sense of humor! >>>Gwen [quoted text clipped - 3 lines] > A cat can be the best companion sometimes......:-) > We have two of them around here... Anthony Shipley - 07 Jan 2006 05:02 GMT >We have two of them around here... Ditto. One very aged Ginger cat that weighs only about a ginger bisciut and a 4 y.o. tortoise shell who likes scratching me (and making me bleed -:)
anthony shipley
Run away with me; I can make you unhappy.
Evelyn Ruut - 07 Jan 2006 14:05 GMT >>We have two of them around here... > > Ditto. One very aged Ginger cat that weighs only about a ginger bisciut > and a 4 > y.o. tortoise shell who likes scratching me (and making me bleed -:) I have a Ginger colored male that my mother in law rescued as a half starved, filthy, tiny, skinny kitten. We took it from her and brought it here, because at that time the poor woman couldn't even take care of herself, much less a very sick kitten. Anyway he did survive and became a very nice cat. He loves me the best and is so affectionate he is almost a pest.
Then we have a black female cat too. My son rescued the mother who immediately had a bunch of kittens. He called me up and told me I was taking one :-) That one is my husband's favorite and she sleeps with him and follows him everywhere. When he takes the dog out for a walk and she misses getting out in time, she cries by the door, angry that she didn't get to go out too.
The pair of them hunt together and have managed to clear the entire neighborhood of mice and other small furry things...... chipmunks, baby squirrels, moles... Fortunately they don't often kill any birds, but they do like to kill frogs down by the pond.
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Evelyn (to reply to me personally, remove 'sox')
James Semmel - 10 Jan 2006 19:20 GMT Anthony,
Just about everyone experiences some lapse in memory as their posture clearly deteriorates into old age. By maintaining good posture, one can preserve the function of many organs, including the brain.
james
pellmellwillynilly@hotmail.com - 20 Jan 2006 05:29 GMT I'm not well enough educated in biomechanics to evaluate your webpages, but nothing looks amiss to me. I'd be curious, though, to know what today's doctors and chiropractors think of the chiropodist you've used so heavily as a resource. I'd also be curious to know what you think of Nia.
> Don't be too quick to dismiss the shoe theory. I know it seems > unusual, but it's not that far-fetched. [quoted text clipped - 7 lines] > > james James Semmel - 20 Jan 2006 18:13 GMT Nia,
I think the shoe-Alzheimer's connection is very accessible. It just requires an open mind, but certainly not an advanced degree.
Please let me know if you have any questions.
james
pellmellwillynilly@hotmail.com - 22 Jan 2006 01:44 GMT > Nia, > [quoted text clipped - 4 lines] > > james What I wrote was this:
"I'd be curious, though, to know what today's doctors and chiropractors think of the chiropodist you've used so heavily as a resource. I'd also be curious to know what you think of Nia."
My name is not Nia. I want to know what you think of Nia. Try this:
www.nia-nia.com
I also want to know what today's doctors and chiropractors think of the chiropodist you've used so heavily as a resource.
Those are my questions.
Pell
James Semmel - 22 Jan 2006 19:18 GMT Pell,
I looked at the website you provided, and it seems to me that standing posture and gait are more fundamental considerations. After optimizing the posture, specialized exercises and movements, such as the type you inquired about, can be attempted, but in the beginning the basic activities of daily life are sufficient. Indeed, daily life may be more than some can handle.
Chiropodist Dr. Simon Wikler corresponded with a number of doctors and researchers on the subject of shoes and degenerative disease, but he passed away around 1990. There may be a few practicing doctors left who know of him.
The distinguished orthopedist Dr. Joel Goldthwait was another outstanding pioneer in the field of posture and degenerative disease. I can assure you that none of today's researchers or doctors has seen his work, which occurred during the first half of the 20th century.
I also utilized the contributions of podiatrist Dr. William Rossi, who clearly demonstrated in his work that shoes fundamentally influence the posture and gait of any wearer. Dr. Rossi passed away just a few years ago, and he's well known to many podiatrists, despite his viewpoints that go against the grain of the profession. (Shoes obviously cause a number of foot ills, but it seems like today's podiatrists are slow to recognize that.)
Basically, I just put the three together to make what I feel are obvious extensions. Dr. Rossi found that shoes cause poor posture, and Dr. Goldthwait found that poor posture causes degenerative diseases; Dr. Wikler was the first to discover that shoes are a cause of illness in humans. Alzheimer's disease is one of those that I now consider to be obviously caused by footwear.
james
pellmellwillynilly@hotmail.com - 22 Jan 2006 22:40 GMT > Pell, > [quoted text clipped - 4 lines] > activities of daily life are sufficient. Indeed, daily life may be > more than some can handle. Interesting. My impression of Nia -- via the website and my personal experience with it -- is that it's based on the premise that barefoot is best for many things, among them developing posture and gait. I had been thinking that the Nia and yoga people might be good avenues for your ideas. Likewise biomedical engineers or others educated in the body as well as engineering.
> Chiropodist Dr. Simon Wikler corresponded with a number of doctors and > researchers on the subject of shoes and degenerative disease, but he > passed away around 1990. There may be a few practicing doctors left > who know of him. <snip>
> The distinguished orthopedist Dr. Joel Goldthwait was another > outstanding pioneer in the field of posture and degenerative disease. <snip>
> I also utilized the contributions of podiatrist Dr. William Rossi, who <snip>
> Basically, I just put the three together to make what I feel are > obvious extensions. Dr. Rossi found that shoes cause poor posture, and > Dr. Goldthwait found that poor posture causes degenerative diseases; > Dr. Wikler was the first to discover that shoes are a cause of illness > in humans. Alzheimer's disease is one of those that I now consider to > be obviously caused by footwear. It makes a lot of sense to tie together the views of these people. What doesn't make as much sense is that they seem so unknown when they made presumably fundamental discoveries -- and if their research was sound, which much research is not. Were their findings not published in peer-reviewed journals? Were the findings somehow discredited?
It's not as though science throws away ideas just because they're 50 years old. After all, we are all familiar with the findings of Galileo Galilei, Isaac Newton, Edward Jennings, Marie Curie, and Jonas Salk.
I don't know where else you've tried to present your ideas, but you're not finding the right audience, or if you have found it, they've seen holes in your theory. You need to find people sufficiently educated to evaluate your ideas and sufficiently connected to help you get your ideas to the people who can test them (as in peer-reviewed journals). Those people aren't on this newsgroup!
James Semmel - 23 Jan 2006 18:48 GMT Pell,
Dr. Wikler published his seminal paper on the subject of shoes and disease in the Journal of the National Association of Chiropodists, volume 40, number 8, August 1950 in a paper titled "Foot Defects as Possible Etiological Factors in Cancer." (Note that the JNAC became the Journal of the American Podiatry Association later in that decade, and the JAPA became today's Journal of the American Podiatric Medical Association.) It's rather humbling to realize that the medical literature already contained the answer.
Yoga people have been extremely resistant to the idea that shoes cause heart disease, cancers, and Alzheimer's disease. Actually, the Society for Barefoot Living (an internet group of people who like bare feet) is the most skeptical--go figure!
I wholeheartedly disagree that my footbath/breathing therapy is only for the "educated." Indeed, the commoner of today knows much more about the prevention of infectious disease using soap, than did the top scientists and doctors of 150 years ago; the same will hold true for future, unshod generations naturally preventing Alzheimer's disease, which today's most eminent researchers and specialists have completely failed to cure.
james
pellmellwillynilly@hotmail.com - 23 Jan 2006 23:44 GMT > Pell, > [quoted text clipped - 6 lines] > Association.) It's rather humbling to realize that the medical > literature already contained the answer. Good info. Thanks.
> Yoga people have been extremely resistant to the idea that shoes cause > heart disease, cancers, and Alzheimer's disease. Actually, the Society > for Barefoot Living (an internet group of people who like bare feet) is > the most skeptical--go figure! Barefoot Living people don't sound very scientific, but I'm surprised that the yoga people don't know their own theories well enough to embrace bare feet.
> I wholeheartedly disagree that my footbath/breathing therapy is only > for the "educated." I wasn't referring to understanding what to do but why to do it, and I didn't mean about the footbath/breathing therapy, which I never saw on your website. I was referring to all the theory about why and how posture is affected by feet and disease effected by bad posture. BTW, I'm no slouch intellectually. I hold two master's degrees (neither in a science field) and an advanced certificate in publishing. If I got bogged down in your writing because of my lack of background the "commoner of today" is going to stop reading even sooner.
To evaluate the theories you've set forth takes a knowledge and understanding of anatomy and physiology that neither the "commoner of today" or I have. That's why people on this newsgroup -- "commoners of today" and sometimes rather educated ones -- are accusing you of being a troll or obsessed with feet. They don't have the education they need to evaluate your proposals.
I do not have the time or energy to return to school for courses in anatomy and physiology; I spend 12-16 hours a day teaching and writing. I don't have time to slog through every word on your website. And, given the fact that I have to take your theories on faith rather than weighing them against knowledge I don't have, it makes no sense for me to attempt to study your website any more than I have. Likely no one else you've approached with your ideas has that time or energy.
I'm telling you as plainly as I can that you need properly educated people to evaluate your theories. You need readers who do not have to believe what you write but can consider it in the context of scientific knowledge and understanding that they already possess. Only that kind of person can intelligently agree or disagree with you, and if they agree, help you get your ideas to the right forum.
That said, what you choose to believe is beyond my control.
James Semmel - 24 Jan 2006 19:19 GMT Pell,
I couldn't disagree with you more on the need to be "educated." My shoe-Alzheimer's discovery was not preceded by a doctoral degree in anatomy and physiology; it simply required an open mind. The famous endocrinologist, Dr. Hans Selye, who first applied the concept of stress to medicine in pioneering the general adaptation syndrome, had a word about discovery in his book about "The Stress of Life":
"There are two ways of detecting something that no one has yet seen: one is to aim at the finest detail by getting as close as possible with the best available analyzing instruments; the other is merely to look at things from a new angle where they show hitherto unexposed facets. The former requires money and experience; the latter presupposes neither; indeed, it is actually aided by simplicity, the lack of prejudice, and the absence of those established habits of thinking which tend to come after long years of work. The general adaptation syndrome could have been discovered during the Middle Ages, if not earlier; its recognition did not depend upon the development of any complicated pieces of apparatus, new techniques of observation, nor even upon much training, ingenuity, or intelligence, as far as that goes, but merely upon an unbiased state of mind, a fresh point of view."
james
James Semmel - 11 Jan 2006 18:24 GMT I'm really surprised that nobody is even willing to consider the posture-Alzheimer's disease connection. There is strong physical evidence to support my idea, and I even outlined a treatment that can be scientifically evaluated. Is there any researcher or caregiver who is interested?
james
James Semmel - 14 Jan 2006 21:36 GMT My idea is not that far-fetched. Isn't there anyone who is even willing to consider it and try to understand it better?
james
Anthony Shipley - 14 Jan 2006 21:49 GMT >My idea is not that far-fetched. Isn't there anyone who is even >willing to consider it and try to understand it better? Without argument and factual support it's worth nothing.
anthony shipley
Run away with me; I can make you unhappy.
James Semmel - 16 Jan 2006 20:42 GMT Indeed, I have even put forth a treatment based upon my anatomical and physiological findings that footwear is the fundamental cause of Alzheimer's disease. The treatment can be scientifically or clinically evaluated with minimal resources. As we engineers like to say, "The proof of the pudding is in the eating."
I realize that it's a crazy suggestion that such a mechanical object as a shoe could result in a disease like Alzheimer's. Yet researchers have already searched, with the best technology available, and found no definite external cause. The cause must therefore be internal, i.e., muscle tension influenced by gravity. I pick on shoes because they are the most important factor influencing that muscle tension, and if we raised children to be barefoot, as was done prior to Auguste D. (Dr. Alzheimer's first clinical case of the disease), then Alzheimer's disease would become rare in society as it once was.
I think the facts are there for anyone to see, but nobody is willing to look and carefully examine.
james
Evelyn Ruut - 16 Jan 2006 21:15 GMT I am sure nobody is interested in looking further into your theories because it doesn't make a lick of sense to me.
Alzheimers is a brain disease, not a foot disease.
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Evelyn (to reply to me personally, remove 'sox')
> Indeed, I have even put forth a treatment based upon my anatomical and > physiological findings that footwear is the fundamental cause of [quoted text clipped - 16 lines] > > james James Semmel - 17 Jan 2006 17:37 GMT Evelyn,
The brain evolved in an upright posture that was inherently dependent on the foot. Thus, what happens at the feet fundamentally determines what happens throughout the entire body, including the brain.
Unfortunately, researchers are zoomed way in to the brain, without consideration of the larger environment that is actually what we call a human being.
james
Anthony Shipley - 16 Jan 2006 23:03 GMT >I think the facts are there for anyone to see, but nobody is willing to >look and carefully examine. If shoes cause AD, why are there so many people without AD?
anthony shipley
Run away with me; I can make you unhappy.
James Semmel - 17 Jan 2006 17:37 GMT Anthony,
There are millions of people now with Alzheimer's disease. In fact, the plague of Alzheimer's disease spread during the 20th century, the first one following the modern manufactured shoe.
Given the footwear changes of recent decades, the children of today will be experiencing AD at younger ages, and so the 21st century will see even more people with dementia.
james
Evelyn Ruut - 17 Jan 2006 18:53 GMT > Anthony, > [quoted text clipped - 7 lines] > > james When the only tool you have is a hammer, everything looks like a nail.
Back before manufactured shoes people died much younger than they do today, therefore they seldom lived long enough for alzheimers to kick in.
Nowadays there is greater longevity and that is why there are more cases on record..... that and better diagnostics.
Figures can lie and liars can figure.
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Evelyn (to reply to me personally, remove 'sox')
James Semmel - 18 Jan 2006 18:23 GMT Evelyn,
Alzheimer's disease is considered an age-related condition, meaning that it is not a natural consequence of aging cells.
You might also consider the health history of the presidents of the United States, most of whom outlived the commoners of their time. Several of the founding fathers lived past 80, but none developed Alzheimer's disease as did a later president.
Even the first clinical case, presenting to Dr. Alzheimer about 100 years ago, wasn't that old for her time. She was among the first children growing up wearing a modern, manufactured shoe.
james
Evelyn Ruut - 18 Jan 2006 18:51 GMT James, I am sorry to tell you that my father has worn shoes all his life, usually ill fitting ones at that, he is 93 and as we speak he is doing his very complicated taxes. I really believe there is absolutely no merit to your theory.
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Evelyn (to reply to me personally, remove 'sox')
> Evelyn, > [quoted text clipped - 11 lines] > > james James Semmel - 18 Jan 2006 20:45 GMT Evelyn,
You are not alone in your belief. Since making my shoe discovery in 2003, I've corresponded with all of the major Alzheimer's disease research organizations and patient outreach, and every single one has turned down the subtle idea. I've written to hundreds of researchers and doctors, but not one is even willing to consider my treatment.
Nonetheless, if footwear does not cause Alzheimer's disease in humans, then you ought to have a really easy time discrediting my hypothesis; in other words, there must be something obviously wrong with it.
Can you please tell me what I am overlooking in my postural (biomechanical) viewpoint of Alzheimer's disease?
james
Evelyn Ruut - 18 Jan 2006 21:25 GMT > Evelyn, > [quoted text clipped - 12 lines] > > james Since so very many highly accredited individuals seem to discredit your hypothesis, as well as the common person, maybe you ought to start searching for a cause at the other end of the body.
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Evelyn (to reply to me personally, remove 'sox')
Gwen Love - 18 Jan 2006 21:38 GMT Evelyn, I think that would be a very good decision on his part. Gwen
>> Evelyn, >> [quoted text clipped - 16 lines] > hypothesis, as well as the common person, maybe you ought to start > searching for a cause at the other end of the body. Evelyn Ruut - 18 Jan 2006 22:59 GMT > Evelyn, I think that would be a very good decision on his part. > Gwen LOL! Yep.
There are quite a few things that seem to increase the odds of getting it. Head injuries, not using ones mind much in life, diabetes increases the incidence as well. None of these things takes place in the foot.
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Evelyn (to reply to me personally, remove 'sox')
>>> Evelyn, >>> [quoted text clipped - 16 lines] >> hypothesis, as well as the common person, maybe you ought to start >> searching for a cause at the other end of the body. Anthony Shipley - 19 Jan 2006 00:51 GMT >There are quite a few things that seem to increase the odds of getting it. >Head injuries, not using ones mind much in life, diabetes increases the >incidence as well. None of these things takes place in the foot. Evelyn, unrelated entirely to the foot fetishist, can you cite any papers connecting head injuries to A.D (because I did have one).
As for A.D. and shoes, I think we'll find the connection halfway the head and feet :-)
anthony shipley
Run away with me; I can make you unhappy.
Evelyn Ruut - 19 Jan 2006 03:18 GMT >>There are quite a few things that seem to increase the odds of getting it. >>Head injuries, not using ones mind much in life, diabetes increases the [quoted text clipped - 6 lines] > and > feet :-) Hi Anthony, I have had a couple of serious head injuries also. I am not good at doing that kind of research but I have read it in places that one might be inclined to trust (at least trustworthy over dubious internet nut cases like our footsie guy :-)
Below is a post from September 19th 2004 from our own Mary Gordon who posts here often, (and who does this kind of research very thoroughly) copied and pasted here.
Head traumas are listed among the causes.
*********** (begin quoted material)
The usual drill is to start with a full physical including a review of medical history AND all medications the person is on. What they are looking for are any conditions that can cause confusion, memory loss, fuzzy thinking etc. OTHER than Alzheimer's and other incurable progressive dementias. After all, in an older person who may have a constellation of medical issues, problems can brew and fly under the detection radar due to the distraction of other medical concerns i.e. the doctor is so focussed on the diabetes and the heart problem that the brewing thyroid issue goes undetected. It can also happen that a person is seeing a number of specialists and no one really knows ALL the medications someone is taking - and interactions can be causing problems. A good physical should also involve blood tests for thiubngs like pernicious anemia and thyroid function.
Once the obvious non-AD things are ruled out, the next step is usually a referral to a neurologist or psychiatrist with a speciality in dementias. Once there, its common to have a number of other tests, such as various kinds of head scans. At the same time, my MIL also had a comprehensive assessment of her deficits - they wanted to know exactly how impaired she was, but also in what areas, since different causes of dementia can cause completely different sets of deficits - and the resulting deficits result in characteristic behaviour patterns.
Essentially, AD is only diagnosed by ruling out everything else it can be, because although they are getting closer with various kinds of scans, the only way to be 100% sure would be a brain biopsy, rarely done for obvious reasons!
Just to give you an idea of what they are looking for and trying to rule out, here is a list of things that can cause dementia, or dementia like issues (and its not a complete list, just some of the biggies!)
Degenerative
Alzheimer's Disease Parkinson's Disease Dementia with Lewy Bodies Progressive Supranuclear Palsy Multiple System Atrophy Huntington's Disease Pick's Disease Frontotemporal (chromosome 17) Dementia Corticobasal Ganglionic Degeneration The Parkinsonian Dementia Complex of Guam Dementia Lacking Distinctive Histological Features
Vascular
Multiple Infarction Dementia Strategic Infarction Dementia Lacunar State Binswanger's Disease (Subcortical Ischemic Encephalopathy) Vasculitis Subarachnoid Hemorrhage
Infection
Fungal Meningitis Syphilis AIDS Dementia Creutzfeldt-Jacob Disease (and other Prion diseases) Post Herpes Simplex Encephalitis
Psychiatric
Depression Alcohol abuse Drug use or abuse (or interactions/side effects) Personality Disorder Anxiety Disorder
Toxic/Metabolic
B12 deficiency Thyroid deficiency System failure including liver, renal, cardiac, respiratory Heavy metal toxicity Toxin exposure e.g. glue sniffing
Trauma
Subdural hematoma Closed head injury Open head injury Pugilistic brain injury Anoxic brain injury
Tumor
Glioblastoma Lymphoma Metastatic tumor
Other
Symptomatic Hydrocephalus (Normal Pressure Hydrocephalus)
Hope this helps
Mary G.
*****
(end quoted material)
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Evelyn (to reply to me personally, remove 'sox')
Gwen Love - 19 Jan 2006 04:48 GMT Anthony, the neurologist asked if my husand had had a head injury because that could contribute to AD. He did have one in his middle teens. Gwen
>>There are quite a few things that seem to increase the odds of getting it. >>Head injuries, not using ones mind much in life, diabetes increases the [quoted text clipped - 10 lines] > > Run away with me; I can make you unhappy. James Semmel - 19 Jan 2006 17:29 GMT Evelyn,
Actually, thus far nobody has found anything wrong with my discovery. You said it has no merit, but for what reason? What have I overlooked? What flaw does it have?
If there's something obviously wrong with my discovery or treatment, then please tell me what it is so that I can make refinements or corrections.
Thanks, james
James Semmel - 22 Jan 2006 18:30 GMT Evelyn,
I'm genuinely interested in why you don't see any merit to my shoe-Alzheimer's discovery. Did I overlook something? Did I get something wrong? These points are important to me so that I can make the necessary refinements.
Please let me know. Thanks,
james
Anthony Shipley - 19 Jan 2006 00:46 GMT >Evelyn, > [quoted text clipped - 9 lines] >years ago, wasn't that old for her time. She was among the first >children growing up wearing a modern, manufactured shoe. Given the frequent comments about the difficulty of diagnosing A.D., how do we know Alzheimer was right?
anthony shipley
Run away with me; I can make you unhappy.
James Semmel - 19 Jan 2006 17:33 GMT Anthony,
Dr. Alzheimer was the first to use a microscope in analyzing brain tissue from a patient with the disease. He performed his studies when my grandmother was a little girl.
james
Anthony Shipley - 18 Jan 2006 04:04 GMT >Anthony, > [quoted text clipped - 5 lines] >will be experiencing AD at younger ages, and so the 21st century will >see even more people with dementia. I see what you mean....... but we could also claim that A.D. is a result of chemicals in paint, glue, preservatives, kids having to carry heavy knapsacks and prophylactic condoms. More likely, it was all that time kneeling in church that caused A.D.
Even the fumes given off by car tyres and fuel. Does removing a man's foreskin reduce he liklihood of developing A.D. (is weight a factor?).
anthony shipley
Run away with me; I can make you unhappy.
Evelyn Ruut - 18 Jan 2006 12:07 GMT >>Anthony, >> [quoted text clipped - 17 lines] > foreskin > reduce he liklihood of developing A.D. (is weight a factor?). Anthony, you may have been diagnosed with AD but you are an intelligent guy.
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Evelyn (to reply to me personally, remove 'sox')
James Semmel - 18 Jan 2006 18:29 GMT Anthony,
You bring up many possibilities as the cause of Alzheimer's disease, but the shoe stands out as the most overlooked. The shoe is the only thing capable of changing the essence of what it means to be human, i.e., to have a foot. AD is all about losing what it means to be human, and it seems to me that the shoe is the only object capable of such a 'feet'.
The other primates have a brain, a heart, a stomach, and other features. But none have a foot with a big toe that points ahead for walking. We must question what happens to the body when the position of that big toe changes.
james
June - 18 Jan 2006 19:15 GMT > Anthony, > [quoted text clipped - 11 lines] > > james Ok Troll enough already. Anyone can type James Semmel into google and see all the diseases this idiot has come up with that are caused by shoes. Everything from Crohn's Disease to Osteoporosis. Get a life and get lost!!!!
Evelyn Ruut - 18 Jan 2006 19:31 GMT >> Anthony, >> [quoted text clipped - 16 lines] > Everything from Crohn's Disease to Osteoporosis. Get a life and get > lost!!!! I cannot for the life of me understand what these wackos get out of being a troll......
OK I will grant you that some are genuinely crazy (as in psychotic), but I wonder how it is that these guys don't know how stupid their ideas sound. Geez, I could invent a better wacko theory without half trying!
 Signature
Best Regards,
Evelyn (to reply to me personally, remove 'sox')
Anthony Shipley - 19 Jan 2006 01:04 GMT >OK I will grant you that some are genuinely crazy (as in psychotic), but I >wonder how it is that these guys don't know how stupid their ideas sound. >Geez, I could invent a better wacko theory without half trying! You're on!
:-) anthony shipley
Run away with me; I can make you unhappy.
June - 19 Jan 2006 21:36 GMT > I cannot for the life of me understand what these wackos get out of being > a troll...... > > OK I will grant you that some are genuinely crazy (as in psychotic), but I > wonder how it is that these guys don't know how stupid their ideas sound. > Geez, I could invent a better wacko theory without half trying! I got this e-mail today perhaps James could figure out what's behind some of these conundrums and leave us alone:
IDLE THOUGHTS OF A RETIRED PERSON
I planted some birdseed. A bird came up. Now I don't know what to feed it.
I had amnesia once -- or twice.
I went to San Francisco. I found someone's heart. Now what?
Protons have mass? I didn't even know they were Catholic.
All I ask is a chance to prove that money can't make me happy.
If the world were a logical place, men would ride horses sidesaddle.
What is a "free" gift? Aren't all gifts free?
They told me I was gullible ... and I believed them.
Teach a child to be polite and courteous in the home and, when he grows up, he'll never be able to merge his car onto a freeway.
Two can live as cheaply as one... for half as long.
Experience is the thing you have left when everything else is gone.
What if there were no hypothetical questions?
The shampoo promised me extra body and I gained three pounds.
One nice thing about egotists: They don't talk about other people.
When the only tool you own is a hammer, every problem begins to look like a 20 penny nail.
A flashlight is a case for holding dead batteries.
What was the greatest thing before sliced bread? Hmmmm?
My weight is perfect for my height -- which varies.
I used to be indecisive. Now I'm not sure.
The cost of living hasn't affected its popularity.
How can there be self-help "groups"?
Is there another word for synonym?
Where do forest rangers go to "get away from it all"?
The speed of time is one-second per second.
Is it possible to be totally partial?
What's another word for thesaurus?
Is Marx's tomb a communist plot?
If swimming is so good for your figure, how do you explain whales?
Show me a man with both feet firmly on the ground, and I'll show you a man who can't get his pants off.
It's not an optical illusion. It just looks like one.
Is it my imagination, or do buffalo wings taste like chicken?
.........June
Gwen Love - 19 Jan 2006 22:38 GMT June, I like those. Had seen some of them but enjoyed them again too. Gwen
>> I cannot for the life of me understand what these wackos get out of being >> a troll...... [quoted text clipped - 75 lines] > > .........June Anthony Shipley - 19 Jan 2006 01:03 GMT >You bring up many possibilities as the cause of Alzheimer's disease, >but the shoe stands out as the most overlooked. The shoe is the only [quoted text clipped - 7 lines] >walking. We must question what happens to the body when the position >of that big toe changes. James, you obviously belong to that species of ape that has its foot firmly parked in the other end of its leg.
anthony shipley
Run away with me; I can make you unhappy.
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