Hi all,
A few days ago my mum, who is looking after my dad at home, who has
Alzheimer's, took one of his 50 mg quetiapine (anti-psychotic) pills
by mistake.
She went for a short walk and only just made it back to the house. She
found that she could'nt speak at all, was very unsteady on her feet,
and fell asleep for 4 hours. Her tongue still feels heavy, and her
speech is still not fully back to normal. Also, she couldn't stand
anything touching her legs.
We used to think that these symptoms in my dad were due to the Az, but
this is now the third drug that may be making things worse rather than
better. He was previously on Haliperidol, which turned him into a
zombie, and was taking a sleeping pill, which turned out not to be
necessary.
Does anyone have similar experiences ? In any case I hope this might
prompt others to ask the question "are these drugs actually helping ?"
MikeC
Dennis P. Harris - 02 Jan 2006 19:17 GMT
> She went for a short walk and only just made it back to the house. She
> found that she could'nt speak at all, was very unsteady on her feet,
[quoted text clipped - 5 lines]
> this is now the third drug that may be making things worse rather than
> better.
the effect on someone with an overactive or overstimulated brain
will be entirely different than on someone with "normal" neural
activity. if he was taking it to reduce hallucinations or
delusions, its effect might on him would be completely different.
if the side effect bother him, then yes, it might be time to try
another anti-psychotic. whatever you do, don't cold-turkey him
of the meds without consulting his doctor. suddenly quitting
some psych meds can have some really bad results.
Mary_Gordon@tvo.org - 02 Jan 2006 21:22 GMT
There have been some studies suggesting that seroquel it does nothing
for the treatment of agitation in people with dementia and actually
causes significantly greater cognitive decline.
Why quetiapine? Why not some other anti-psychotic? Does he have
Parkinson's or Lewy Body? I'd be asking the doctor to wean him off the
stuff to see what happens, and get him onto something else if his
agitation returns.
Don't assume your mother's reaction would be the same as your dad's.
Some people are obviously much more sensitive to meds like that than
others, and she did take an out of the blue dose aimed at your dad, who
doubtless got to that dose more gradually.
M.
Tim - 03 Jan 2006 18:57 GMT
> Hi all,
>
[quoted text clipped - 18 lines]
>
> MikeC
Antipsychotics can make you very drowsy. 25mgs x 2 daily Seroquel used
to knock me for six ditto 10mgs Zyprexa.
My wife was on 10mgs zyprexa orodispersible and it didn't have any kind
of 'zombifying' effect.
Some good stuff about elderly and aps can be found at Medscape.

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